Zofer 4 Tablet 10's

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Reviewed By Sunny S , MBBS

MRP ₹58

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Prescription drug

Whats That

About Zofer 4 Tablet

Zofer 4 Tablet belongs to a group of medications called ' anti-emetics' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Zofer 4 Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Zofer 4 Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Zofer 4 Tablet as prescribed. Your doctor will advise you on how often you take Zofer 4 Tablet based on your medical condition. A person taking Zofer 4 Tablet often experience side effects that include a feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Although, not every person faces the side effects of Zofer 4 Tablet , and even some of the unpleasant effects of Zofer 4 Tablet do not require medical attention.

The use of Zofer 4 Tablet is restricted in persons who are allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing liver, kidney, or heart disorders. Zofer 4 Tablet should be used during pregnancy or breastfeeding after consulting a doctor. Zofer 4 Tablet contains lactose so tell your doctor if you have an intolerance to some sugars.

Uses of Zofer 4 Tablet

Nausea, Vomiting

Directions for Use

Tablet: It can be taken with or without a meal as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not break, crush or chew it. Oral disintegrating tablet/Mouth dissolving tablet (tablet MD): Check the label for directions before use. Do not handle the tablet with wet hands. Place the tablet in the mouth and allow it to dissolve. Do not swallow it as a whole.Syrup/Suspension: Shake the bottle well before use and take it as prescribed by your doctor with a measuring cup or spoon.

Medicinal Benefits

Zofer 4 Tablet belongs to a group of medications called anti-emetics used to prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above 4 years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Zofer 4 Tablet acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

Side effects of Zofer 4 Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drowsiness

Get enough sleep. Maintain a regular sleep cycle.
Eat a healthy diet and exercise regularly.
Manage stress with yoga or meditation.
Limit alcohol and caffeine.
Avoid driving or operating machinery unless you are alert.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Sensation Of Warmth/ Flushing

Avoid rubbing or scratching the affected area, as this can cause further irritation and discomfort.
Consider using a humidifier to add moisture to the air and help reduce the sensation.
Seek medical attention if the sensation is severe, persistent, or worsens over time.
Avoid extreme temperatures, such as hot or cold showers, that can exacerbate the sensation.
Wear light, breathable clothing to help keep the body cool and reduce the sensation.
Avoid triggers that can cause the sensation, such as spicy foods or hot drinks.
Use cool compresses or fans to help lower body temperature and reduce the sensation.

General Feeling Of Discomfort Or Unease

Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:

If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
Inform your doctor about the medication you're taking and the symptoms you're experiencing.
Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.

Fatigue

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Tell your doctor if you are dealing with an uneven heart, liver problems, or any other problem. Tell your doctor if you are taking medicine for epilepsy, cancer medicines, and abnormal heartbeats. Zofer 4 Tablet may affect a person's ability to drive. Therefore, should avoid driving or operating any machine. People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Zofer 4 Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Zofer 4 Tablet daily. Zofer 4 Tablet should be used during pregnancy or breastfeeding after consultation with a doctor. Taking Zofer 4 Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug-Drug Interactions

OndansetronZiprasidone

Critical

OndansetronAlmotriptan

Severe

Drug-Drug Interactions

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OndansetronZiprasidone

Critical

How does the drug interact with Zofer 4 Tablet:
Taking Zofer 4 Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zofer 4 Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

OndansetronAlmotriptan

Severe

How does the drug interact with Zofer 4 Tablet:
When Zofer 4 Tablet, is taken with almotriptan it can cause serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Zofer 4 Tablet along with almotriptan can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.

OndansetronTapentadol

Severe

How does the drug interact with Zofer 4 Tablet:
Using Tapentadol together with Zofer 4 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking Zofer 4 Tablet along with tapentadol can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.

OndansetronLithium

Severe

How does the drug interact with Zofer 4 Tablet:
Taking Zofer 4 Tablet with lithium can increase the risk of serotonin syndrome a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Zofer 4 Tablet along with lithium can result in an interaction but can be taken together if prescribed by a doctor. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools, or fast or rapid heartbeats during therapy, consult a doctor. Do not stop using any medications without talking to a doctor.

OndansetronCeritinib

Severe

How does the drug interact with Zofer 4 Tablet:
Taking ceritinib together with Zofer 4 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Zofer 4 Tablet along with ceritinib can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

OndansetronVortioxetine

Severe

How does the drug interact with Zofer 4 Tablet:
When Zofer 4 Tablet, is taken with Vortioxetine it can cause serotonin syndrome (A condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Zofer 4 Tablet along with Vortioxetine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.

OndansetronCabozantinib

Severe

How does the drug interact with Zofer 4 Tablet:
Taking Zofer 4 Tablet with cabozantinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Zofer 4 Tablet along with cabozantinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.

OndansetronHydroxychloroquine

Severe

How does the drug interact with Zofer 4 Tablet:
Taking Zofer 4 Tablet with hydroxychloroquine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Zofer 4 Tablet along with hydroxychloroquine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.

OndansetronRibociclib

Severe

How does the drug interact with Zofer 4 Tablet:
Taking Zofer 4 Tablet with ribociclib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Zofer 4 Tablet along with ribociclib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.

OndansetronParoxetine

Severe

How does the drug interact with Zofer 4 Tablet:
When Zofer 4 Tablet is taken with paroxetine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Zofer 4 Tablet along with paroxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medication without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting.
One should avoid taking greasy or oily foods as this food triggers nausea and vomit.
Eat cool foods instead of hot and spicy foods.
Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting.

Side Effects of Zofer 4 Tablet

Sensations of flushing
Constipation
Headache
Confusion
Dizziness
Fast heartbeat
Fever
Headache
Shortness of breath
Weakness

Habit Forming

No

Therapeutic Class

ANTIEMETICS

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How soon does Zofer 4 Tablet ondansetron work?

Zofer 4 Tablet is an anti-sickness medicine that takes about 1-2 hours to show its action.

I am facing severe constipation, so should I take Zofer 4 Tablet ?

Tell your doctor if you are facing severe constipation as after checking your condition, the doctor will decide that you can take this medicine or not.

Can I drive after taking Zofer 4 Tablet ?

Zofer 4 Tablet may cause changes in the vision, so one should avoid driving or operating any machine that required mental alertness.

What are the certains conditions in which intake of Zofer 4 Tablet is not recommended?

People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Zofer 4 Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Zofer 4 Tablet daily. Taking Zofer 4 Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug-Drug Interactions Checker List

ACETAMINOPHEN
TRAMADOL
IBUPROFEN
PREGABALIN
LORAZEPAM

Special Advise

Do not use Zofer 4 Tablet with Apomorphine as it can cause a sudden fall of blood pressure leading to death or coma.
Zofer 4 Tablet contains 'phenylalanine' so if you have Phenylketonuria (PKU) avoid its intake.

Disease/Condition Glossary

Nausea/Vomiting: Nausea is an uneasy feeling in the stomach that may come and go in waves in which a person feels with a strong urge to vomit. It happens before vomiting. While vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain, or irritation to the stomach. Usually, a person faces nausea and vomiting as the unpleasant effects of cancer therapy after chemotherapy and radiation therapy. It is essential to control vomiting and nausea in cancer patients for performing everyday activities of the day. If not controlled, it can lead to mental changes, loss of appetite, malnutrition, and dehydration.