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Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Pulse Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Zolsoma 5 Tablet

Zolsoma 5 Tablet is a combination medication containing 'sedative-hypnotics' used in the treatment of insomnia. Insomnia is a disorder of sleep that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature due to various complications like stress, anxiety, and breathing problems.

Zolsoma 5 Tablet contains Zolpidem and Melatonin, primarily used to treat insomnia. Zolpidem works by increasing the activity of GABA, which is a chemical messenger in the brain, acting as a natural nerve-calming agent, thereby inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep).  Thus, Zolsoma 5 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Take Zolsoma 5 Tablet as prescribed by your doctor. You are advised to take Zolsoma 5 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take Zolsoma 5 Tablet empty stomach and just before bedtime. In some cases, you may experience nausea, headache, diarrhoea, drowsiness, and dizziness. Most of these side effects of Zolsoma 5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are pregnant, planning to become pregnant, or breastfeeding, please inform your doctor before starting Zolsoma 5 Tablet . Do not stop taking Zolsoma 5 Tablet even if you feel better, as it may lead to unpleasant side effects. Zolsoma 5 Tablet is known to cause drowsiness, so do not drive or operate machinery. Avoid consumption of alcohol as it may reduce the effectiveness of Zolsoma 5 Tablet . Zolsoma 5 Tablet should not be used for daily naps.

Uses of Zolsoma 5 Tablet

Insomnia (sleeplessness).

Directions for Use

Swallow Zolsoma 5 Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Zolsoma 5 Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep). Thus, Zolsoma 5 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep. Appropriate lifestyle changes are recommended along with Zolsoma 5 Tablet to improve the quality of sleep.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Zolsoma 5 Tablet if you are allergic to Zolsoma 5 Tablet or any of its ingredients. If you notice that the tablets are not working as well as they did in the beginning of the treatment, please consult a doctor as you might have developed tolerance to Zolsoma 5 Tablet , and dose adjustment may be required. Zolsoma 5 Tablet contains Zolpidem, a category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth. If you are a breastfeeding mother, it is advised to consult a doctor before using Zolsoma 5 Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a severe condition in which breathing stops and starts repeatedly in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Zolsoma 5 Tablet . Maintain a time gap of a minimum of 8 hours between taking Zolsoma 5 Tablet and driving to reduce the risk of increased adverse effects.

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
How does the drug interact with Zolsoma 5 Tablet:
Using sodium oxybate together with Zolsoma 5 Tablet can significantly increase the risk of severity of low blood pressure, breathing difficulties, fainting and unconsciousness.

How to manage the interaction:
Taking Sodium oxybate with Zolsoma 5 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate consult a doctor immediately. You should refrain from operating any dangerous machinery or driving a car. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zolsoma 5 Tablet:
Taking Zolsoma 5 Tablet with Buprenorphine can cause central nervous system depression, leading to breathing difficulty and unconsciousness.

How to manage the interaction:
Although taking Buprenorphine and Zolsoma 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, or reaction speed, consult a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
ZolpidemAlfentanil
Severe
How does the drug interact with Zolsoma 5 Tablet:
Using Zolsoma 5 Tablet together with Alfentanil may increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Alfentanil and Zolsoma 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, or impairment in judgment consult a doctor. Do not stop using any medications without a doctor's advice.
ZolpidemEsketamine
Severe
How does the drug interact with Zolsoma 5 Tablet:
Taking Zolsoma 5 Tablet with Esketamine increases the effects of Zolsoma 5 Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Esketamine and Zolsoma 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.
ZolpidemPindolol
Severe
How does the drug interact with Zolsoma 5 Tablet:
Taking Zolsoma 5 Tablet with Pindolol may increase the risk of low blood pressure.

How to manage the interaction:
Although taking Pindolol and Zolsoma 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemSufentanil
Severe
How does the drug interact with Zolsoma 5 Tablet:
Using Zolsoma 5 Tablet together with Sufentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Sufentanil and Zolsoma 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zolsoma 5 Tablet:
Using Zolsoma 5 Tablet together with Tapentadol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Zolsoma 5 Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zolsoma 5 Tablet:
Taking Zolsoma 5 Tablet with Ketamine increases the effects of Zolsoma 5 Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Ketamine and Zolsoma 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zolsoma 5 Tablet:
Using Zolsoma 5 Tablet together with Fentanyl can cause central nervous system depression.

How to manage the interaction:
Although taking Fentanyl and Zolsoma 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience dizziness, sleepiness, difficulty concentrating, and impaired judgment. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zolsoma 5 Tablet:
Using Zolsoma 5 Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Zolsoma 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, or reaction speed, avoid driving or operating hazardous machinery consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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MELATONIN-3MG+ZOLPIDEM-5MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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MELATONIN-3MG+ZOLPIDEM-5MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking caffeine with Zolsoma 5 Tablet may increase the blood levels and effects of Zolsoma 5 Tablet. Avoid taking excessive caffeine consumption while being treated with Zolsoma 5 Tablet.

Diet & Lifestyle Advise

  • Do regular exercise during day time.
  • Do not take a nap during day time. Set regular timings to go to bed and wake up.
  • Relax at least 1 hour before bedtime by bathing with warm water, listening to music, or reading a book.
  • Make the bedroom dark and quiet, and ensure that your pillows and mattresses are comfortable.
  • Avoid watching tv, using mobiles or laptops just before bedtime.
  • Limit caffeine intake, including tea, coffee, hot chocolate, cola, and energy drinks, as it may reduce the effectiveness of Zolsoma 5 Tablet .
  • Avoid alcohol consumption as it may increase the risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleepwalking, or sleep-driving.

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zolsoma 5 Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep)

No, Zolsoma 5 Tablet is not recommended for depression patients as it may worsen the condition and increase self-harming or suicidal thoughts. Therefore, if you are suffering from depression or have a history of depression, please inform your doctor before taking Zolsoma 5 Tablet .

You are recommended to take Zolsoma 5 Tablet just before bedtime as it helps to sleep quickly and improves sleep quality. If you forget to take Zolsoma 5 Tablet at night, do not take it in the day time as it may cause drowsiness, confusion and dizziness.

No, you are not recommended to take Zolsoma 5 Tablet with hydrocodone or other opioid pain killers such as oxycodone, naloxone, and tramadol as co-administration of these medicines with Zolsoma 5 Tablet may increase the risk of difficulty in breathing, drowsiness, coma, and even death. However, before using Zolsoma 5 Tablet with any other medicines, you are advised to contact your doctor so that the dose may be adjusted to use safely.

Yes, Zolsoma 5 Tablet may cause dependence (mental and physical effects caused due to compulsion of taking Zolsoma 5 Tablet ) if used in high doses and for a prolonged time. This risk of dependency on Zolsoma 5 Tablet increases in patients who have a history of drug or alcohol abuse.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • HYDROCODONE
  • SERTRALINE
  • CIPROFLOXACIN
  • RIFAMPICIN
  • KETOCONAZOLE
  • ALPRAZOLAM
  • DIPHENHYDRAMINE
  • CYCLOBENZAPRINE
  • GABAPENTIN
  • CIMETIDINE
  • MIDAZOLAM

Special Advise

  • You are advised to take Zolsoma 5 Tablet on an empty stomach as taking Zolsoma 5 Tablet with food may reduce the effect of Zolsoma 5 Tablet .
  • If you are depressed or have depression in the past, please inform your doctor before taking Zolsoma 5 Tablet as it may increase self-harming or suicidal thoughts.
  • If you notice any behavioural side effects such as delusions (false belief), nightmares, irritability, restlessness, aggressiveness, or hallucinations (hear, feel or see things that are actually not present), please contact your doctor.
  • If you are allergic to any sugars, inform your doctor as Zolsoma 5 Tablet contains lactose.

Disease/Condition Glossary

Insomnia: It is a disorder of sleep associated with problems in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature. Acute insomnia may last from one night to a few weeks and occurs due to stress or life changes. Chronic insomnia may last from more than 3 nights per week to more than 3 months. Insomnia is mostly caused due to depression, stress, anxiety, jet lag, shift work, uncomfortable beds, chronic illness, caffeine, nicotine, alcohol intake, or certain medicines. It may be treated using sleeping pills, behaviour therapy, sleep habits changes, and identifying and treating chronic conditions.

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