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Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

ZONISAMIDE-100MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ZONIMID 100MG TABLET

ZONIMID 100MG TABLET belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy (seizures/fits). Epilepsy is a sudden rush of electricity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual’s consciousness, movements, or sensations.

ZONIMID 100MG TABLET contains 'Zonisamide’ that reduces the abnormal and excessive activity of nerve impulses in the brain that cause fits or seizures. Thereby helps in controlling seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual’s consciousness, movements, or sensations. ZONIMID 100MG TABLET is used alone or in combination to treat and prevent partial seizures in adults and children above 6 years of age.

Take ZONIMID 100MG TABLET as prescribed by your doctor. You are advised to take ZONIMID 100MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, irritability, loss of appetite, memory impairment, double vision, confusion, depression, constipation, nausea, headache, uncontrolled movements. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking ZONIMID 100MG TABLET for as long as your doctor has prescribed. Please do not stop taking ZONIMID 100MG TABLET without consulting your doctor to avoid worsening of seizures. Do not take ZONIMID 100MG TABLET if you are pregnant or planning for pregnancy unless prescribed by the doctor. Avoid taking ZONIMID 100MG TABLET while breastfeeding as it may cause side-effects in the breastfed babies. ZONIMID 100MG TABLET should not be given to children unless prescribed. ZONIMID 100MG TABLET causes drowsiness and dizziness, so drive if you are alert. ZONIMID 100MG TABLET should not be given to children unless prescribed. Avoid consuming alcohol along with ZONIMID 100MG TABLET as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience mood swings or suicidal tendencies. ZONIMID 100MG TABLET can cause permanent vision loss, inform your doctor immediately if you have any eye pain, redness, or any changes in your vision. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of ZONIMID 100MG TABLET

Epilepsy/Seizures

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

ZONIMID 100MG TABLET belongs to a group of medicines called anti-convulsants or anti-epileptics. ZONIMID 100MG TABLET is used to treat epilepsy/seizures/fits. Epilepsy is a sudden rush of electricity in the brain. ZONIMID 100MG TABLET works by blocking the sodium and calcium current in the brain and suppress the abnormal and excessive activity of nerve impulses in the brain that cause fits and pain. Thereby help in controlling seizures. ZONIMID 100MG TABLET is used alone or in combination to treat and prevent partial seizures and generalized seizures in adults. ZONIMID 100MG TABLET may be used as solo therapy or in combination in treating and preventing seizures in children above 6 years of age. ZONIMID 100MG TABLET is not associated with any psychological or physical dependence, and there is no potential for abuse.

Storage

Keep ZONIMID 100MG TABLET out of sight and reach of children.
Side effects of Zonimid 100mg Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
  • Limit stimulants like tea, coffee and alcohol.
  • Identify triggers and try managing them.
  • Take a break by scheduling time for yourself.
  • Try creative activities like writing, dancing or painting as it helps release tension.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Regular eye exams can detect conditions causing Involuntary Eye Movement.
  • Alcohol and drugs should be avoided as they can increase the symptoms of nystagmus.
  • Wearing corrective lenses for refractive errors can reduce eye strain and symptoms.
  • Stress management and getting proper sleep can help to reduce symptoms.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Drug Warnings

Do not take ZONIMID 100MG TABLET if you are allergic to Zonisamide or any of its contents. Avoid intake of ZONIMID 100MG TABLET if you are pregnant or planning for pregnancy unless prescribed by the doctor. Breastfeeding mothers should consult the doctor before using ZONIMID 100MG TABLET to pass into the breast milk and affect the baby. ZONIMID 100MG TABLET should not be given to children unless prescribed. Inform your doctor before taking ZONIMID 100MG TABLET if you have or had kidney and liver problems, glaucoma, high levels of ammonia, osteoporosis, depression, heart problems if you have low levels of bicarbonate in blood you have previously suffered from kidney stones. Do not stop taking ZONIMID 100MG TABLET without consulting your doctor to avoid worsening of seizure episodes. ZONIMID 100MG TABLET causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with ZONIMID 100MG TABLET as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience mood swings or suicidal tendencies. ZONIMID 100MG TABLET can cause permanent vision loss, inform your doctor immediately if you have any eye pain, redness, or any changes in your vision.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zonimid 100mg Tablet:
Using buprenorphine together with Zonimid 100mg Tablet may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Concomitant administration of buprenorphine alongside Zonimid 100mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications affect you. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zonimid 100mg Tablet:
Coadministration of Trihexyphenidyl with Zonimid 100mg Tablet can increase the risk or severity of Zonimid 100mg Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Trihexyphenidyl with Zonimid 100mg Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zonimid 100mg Tablet:
Coadministration of Dimenhydrinate with Zonimid 100mg Tablet can increase the risk or severity of Zonimid 100mg Tablet side effects.

How to manage the interaction:
Taking Dimenhydrinate with Zonimid 100mg Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience shortness of breath, palpitations, fever, or excessive sweating, contact a doctor. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zonimid 100mg Tablet:
Using ketamine together with Zonimid 100mg Tablet may increase side effects.

How to manage the interaction:
Co-administration of Ketamine with Zonimid 100mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on how you're breathing. If you notice any of these signs - dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, and respiratory depression - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zonimid 100mg Tablet:
Coadministration of Topiramate with Zonimid 100mg Tablet can increase the risk or severity of Zonimid 100mg Tablet side effects like metabolic acidosis (elevated levels of acid in the blood) and kidney stones.

How to manage the interaction:
Taking Topiramate with Zonimid 100mg Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in confusion, fast heartbeat, fatigue, nausea, vomiting, long and deep breaths, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zonimid 100mg Tablet:
Coadministration of Atropine and Zonimid 100mg Tablet can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking atropine and Zonimid 100mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zonimid 100mg Tablet:
Co-administration of Flavoxate and Zonimid 100mg Tablet may increase body temperature and decrease sweating.

How to manage the interaction:
If you are supposed to take Flavoxate and Zonimid 100mg Tablet together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. Drink plenty of fluids during warm weather and when exercising and contact a doctor if you have decreased sweating or a fever. Avoid activities requiring mental alertness such as driving or operating hazardous machinery, until you know how the medications affect you. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Zonimid 100mg Tablet:
Coadministration of Trospium with Zonimid 100mg Tablet can increase the risk or severity of Zonimid 100mg Tablet side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Trospium with Zonimid 100mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zonimid 100mg Tablet:
Co-administration of Ziprasidone with Zonimid 100mg Tablet can increase the risk or severity of Zonimid 100mg Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Ziprasidone with Zonimid 100mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zonimid 100mg Tablet:
Coadministration of Amitriptyline and Zonimid 100mg Tablet both increase body temperature while decreasing sweating.

How to manage the interaction:
Zonimid 100mg Tablet and Amitriptyline interact, however, if prescribed by a doctor, they can both be used. Some people may experience heat stroke and need to be hospitalized, especially in warm weather and while engaging in intense exercise. Children are especially at risk. If you feel sleepy, uneasy, or lightheaded after taking these medications combined, consult a doctor. Without consulting a doctor, never stop taking medicines.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

ZONIMID 100MG TABLET consists of 'zonisamide' that decreases the brain's excessive and abnormal nerve activity by blocking sodium and calcium currents in your brain and body. This reduces abnormal electrical activity between your nerve cells.

Consult your doctor before taking ZONIMID 100MG TABLET if you are pregnant or planning for pregnancy. Your doctor will prescribe ZONIMID 100MG TABLET only if the benefits outweigh the risks. If you are planning for pregnancy, use contraception while taking ZONIMID 100MG TABLET.

ZONIMID 100MG TABLET should be used with caution during hot weather as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever. To avoid this condition, it is advisable to drink a lot of cold fluid and water, move to a cooler place, especially in summer.

No, ZONIMID 100MG TABLET is not a habit-forming drug. However, it can cause side-effects, especially when you stop taking it suddenly.

Do not discontinue ZONIMID 100MG TABLET without consulting your doctor. To treat your condition effectually continue taking ZONIMID 100MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking ZONIMID 100MG TABLET; your doctor will gradually reduce the dose to avoid precipitating seizures.

Consult your doctor before taking ZONIMID 100MG TABLET if you have had kidney stones. Your doctor will prescribe ZONIMID 100MG TABLET only if the benefits outweigh the risks. ZONIMID 100MG TABLET should be taken with caution in patients with kidney stones. You may be at increased risk of developing more kidney stones. Reduce the risk of kidney stones, drink sufficient water.

Consult your doctor before taking ZONIMID 100MG TABLET if you have glaucoma. ZONIMID 100MG TABLET is contraindicated in patients with narrow-angle glaucoma. ZONIMID 100MG TABLET may cause blindness on long-term use in the case of patients with narrow-angle glaucoma.

Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
  • SERTRALINE
  • FLUOXETINE
  • GABAPENTIN
  • LAMOTRIGINE
  • PREGABALIN
  • PHENYTOIN
  • TOPIRAMATE
  • ARIPIPRAZOLE
  • QUETIAPINE
  • LITHIUM
  • ALPRAZOLAM
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • CHLORPHENIRAMINE
  • CODEINE
  • OXYCODONE
  • TRAMADOL
  • MORPHINE
  • DIPHENHYDRAMINE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • FLUCONAZOLE
  • TRIAZOLAM
  • TROLEANDOMYCIN
  • BROMPHENIRAMINE

Special Advise

  • Regular monitoring of bicarbonate levels while taking ZONIMID 100MG TABLET is advised to prevent low blood bicarbonate levels.
  • ZONIMID 100MG TABLET may cause low blood cell count, so if you have any red or purple spots on the body, let your doctor know about this.

Disease/Condition Glossary

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements, or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

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