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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About Zosa-DSR Capsule 15's

Zosa-DSR Capsule 15's belongs to a group of gastrointestinal agents used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, peptic ulcers and Zollinger-Ellison syndrome.

Zosa-DSR Capsule 15's is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, Zosa-DSR Capsule 15's helps in treating acidity-related problems.

You are advised to take Zosa-DSR Capsule 15's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking Zosa-DSR Capsule 15's if you are pregnant or breastfeeding. Zosa-DSR Capsule 15's may cause dizziness, so drive only if you are alert. Zosa-DSR Capsule 15's should not be given to children as safety has not been established. Avoid consuming alcohol and Zosa-DSR Capsule 15's as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

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Whats That

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Zosa-DSR Capsule 15's

Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, Stomach ulcers

Medicinal Benefits

Zosa-DSR Capsule 15's is a combination of two drugs: Esomeprazole and Domperidone. Zosa-DSR Capsule 15's is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It may also be indicated in the treatment of nausea, vomiting, fullness of the stomach, belching, heavy bloating, heartburn, acidity, gas, upper abdominal pain, erosive oesophagitis, and swallowing problems. Esomeprazole is a proton pump inhibitor that blocks an enzyme called gastric proton pump, responsible for acid production. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscles. Together, Zosa-DSR Capsule 15's helps in treating acidity-related problems.

Side Effects of Zosa-DSR Capsule 15's

  • Dry mouth
  • Stomach pain
  • Diarrhoea
  • Headache
  • Flatulence

Directions for Use

Take Zosa-DSR Capsule 15's 1 hour prior to food. Swallow Zosa-DSR Capsule 15's as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Zosa-DSR Capsule 15's if you are allergic to any of its contents or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, or heart problems. Inform your doctor before taking Zosa-DSR Capsule 15's if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Zosa-DSR Capsule 15's. On long-term treatment, Zosa-DSR Capsule 15's may cause low magnesium levels, vitamin B12 levels, and might increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor if you are pregnant or breastfeeding. Zosa-DSR Capsule 15's may cause dizziness, so drive only if you are alert. Zosa-DSR Capsule 15's should not be given to children as safety has not been established. Avoid consuming alcohol along with Zosa-DSR Capsule 15's as it could lead to increased drowsiness and can elevate the production of stomach acid. A prolonged intake of Zosa-DSR Capsule 15's is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. 

Therapeutic Class

GASTROINTESTINAL AGENTS

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
DomperidoneKetoconazole
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Zosa-DSR Capsule 15's:
Zosa-DSR Capsule 15's may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Zosa-DSR Capsule 15's with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Zosa-DSR Capsule 15's:
Coadministration of Zosa-DSR Capsule 15's with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Zosa-DSR Capsule 15's and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Zosa-DSR Capsule 15's:
Coadministration of Zosa-DSR Capsule 15's with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Zosa-DSR Capsule 15's and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Zosa-DSR Capsule 15's:
Coadministration of Zosa-DSR Capsule 15's with Cisapride can increase the blood levels of Zosa-DSR Capsule 15's.

How to manage the interaction:
There may be a possibility of interaction between Zosa-DSR Capsule 15's and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Zosa-DSR Capsule 15's:
Coadministration of Zosa-DSR Capsule 15's with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Zosa-DSR Capsule 15's and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Zosa-DSR Capsule 15's:
Coadministration of Zosa-DSR Capsule 15's with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Zosa-DSR Capsule 15's and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Zosa-DSR Capsule 15's:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Zosa-DSR Capsule 15's and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Zosa-DSR Capsule 15's:
Combining Mizolastine with Zosa-DSR Capsule 15's can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Zosa-DSR Capsule 15's and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Zosa-DSR Capsule 15's:
Coadministration of Zosa-DSR Capsule 15's with Nefazodone can increase the blood levels of Zosa-DSR Capsule 15's.

How to manage the interaction:
There may be a possibility of interaction between Zosa-DSR Capsule 15's and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Zosa-DSR Capsule 15's:
Coadministration of Zosa-DSR Capsule 15's with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Zosa-DSR Capsule 15's and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • SAQUINAVIR
  • RITONAVIR
  • NELFINAVIR
  • WARFARIN
  • CLOPIDOGREL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • ERLOTINIB
  • TOREMIFENE
  • VANDETANIB
  • VINCAMINE
  • DIAZEPAM
  • PHENYTOIN
  • CILOSTAZOL
  • CISAPRIDE
  • DOLASETRON
  • TACROLIMUS
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • MOXIFLOXACIN
  • PENTAMIDINE
  • TELITHROMYCIN
  • LEVOTHYROXINE
  • METHOTREXATE
  • CITALOPRAM
  • ESCITALOPRAM
  • DIGOXIN
  • HALOFANTRINE
  • HALOPERIDOL
  • PIMOZIDE
  • SERTINDOLE
  • MEQUITAZINE
  • MIZOLASTINE
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • DISOPYRAMIDE
  • DOFETILIDE
  • SOTALOL
  • DILTIAZEM
  • VERAMAPIL

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Special Advise

  • Inform your doctor before taking Zosa-DSR Capsule 15's if you are due to have Chromogranin A blood test.
  • Zosa-DSR Capsule 15's may cause changes in blood tests. Inform the person doing the tests that you are taking Zosa-DSR Capsule 15's.

Author Details

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Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Stomach/Peptic ulcers: They are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Zollinger-Ellison syndrome: It is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting. 

Zosa-DSR Capsule 15's Substitute

Substitutes safety advice
  • Sompraz D 40 Capsule 15's

    by AYUR

    15.90per tablet
  • Nexpro RD 40 Capsule 10's

    16.70per tablet
  • Esogress-D Capsule 10's

    by AYUR

    12.69per tablet
  • Esomac D 40 Capsule 10's

    19.26per tablet
  • Raciper D Capsule 15's

    by AYUR

    15.90per tablet
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