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  1. Home
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  3. Atranza Capsule

Atranza Capsule, Pack of 1 Capsule
Atranza Capsule, Pack of 1 Capsule
Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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Whats That

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Composition :

TRETINOIN-10MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Atranza Capsule

Atranza Capsule belongs to a class of drugs called retinoids (similar to vitamin A). Atranza Capsule is used to treat acute promyelocytic leukaemia (a type of blood problem). Acute promyelocytic leukaemia is a blood cancer that causes a marked increase in a type of immature white blood cells known as promyelocytes in the blood and bone marrow. 

Atranza Capsule contains Tretinoin, a form of vitamin A that works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

Take Atranza Capsule as prescribed. Your doctor will advise you how often you need to take Atranza Capsule based on your medical condition. Some people may experience dizziness, headache, feeling tired, stomach pain, irregular heartbeat, hair loss, bone or joint pain, dry skin and changes in eyesight or hearing. Most of these side effects of Atranza Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Tretinoin, peanuts, soya or any other ingredients in Atranza Capsule, please tell your doctor. Avoid taking Atranza Capsule if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Atranza Capsule as it is excreted into breast milk and may harm the baby. Avoid taking Atranza Capsule if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Atranza Capsule as it may contain sorbitol.

Uses of Atranza Capsule

Acute promyelocytic leukaemia

Directions for Use

Take Atranza Capsule preferably with a meal or as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Atranza Capsule is a form of vitamin A that is primarily used to treat acute promyelocytic leukaemia (a type of blood problem). Atranza Capsule reduces the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.  

Storage

Store in a cool and dry place away from sunlight
Side effects of Atranza Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.

Drug Warnings

If you are allergic to Tretinoin, peanuts, soya or any other ingredients, please tell your doctor. Avoid taking Atranza Capsule if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Atranza Capsule as it is excreted into breast milk and may harm the baby. You are advised to use effective contraceptive methods while using Atranza Capsule to prevent pregnancy. Avoid taking Atranza Capsule if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Atranza Capsule as it may contain sorbitol.

Drug-Drug Interactions

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TretinoinTetracycline
Critical
TretinoinDemeclocycline
Critical

Drug-Drug Interactions

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TretinoinTetracycline
Critical
How does the drug interact with Atranza Capsule:
Coadministration of Atranza Capsule with Tetracycline can increase the risk of pseudotumor cerebri(caused by increased pressure in the brain).

How to manage the interaction:
Taking Atranza Capsule with Tetracycline is not recommended, but can be taken together if prescribed by a doctor. However, if you experience headache, nausea, vomiting, and visual disturbances contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinDemeclocycline
Critical
How does the drug interact with Atranza Capsule:
Combining Atranza Capsule with Demeclocycline can increase the risk of side effects like pseudotumor cerebri (increased pressure in the brain)

How to manage the interaction:
Taking Atranza Capsule with Demeclocycline is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinMinocycline
Critical
How does the drug interact with Atranza Capsule:
Co-administration of Atranza Capsule with Minocycline can increase the risk of side effects like pseudotumor cerebri (increased pressure in the brain)

How to manage the interaction:
Taking Atranza Capsule with Minocycline is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinDoxycycline
Critical
How does the drug interact with Atranza Capsule:
Coadministration of Atranza Capsule with Doxycycline can increase the risk of side effects like vision problems.

How to manage the interaction:
Taking Atranza Capsule with Doxycycline is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinOxytetracycline
Critical
How does the drug interact with Atranza Capsule:
Co-administration of Atranza Capsule with Oxytetracycline can increase the risk of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Oxytetracycline with Atranza Capsule is not recommended as it can be taken if prescribed by a doctor. However, if you experience headaches, nausea, vomiting, and vision problems contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinTranexamic acid
Severe
How does the drug interact with Atranza Capsule:
Co-administration of Atranza Capsule with tranexamic acid may increase the risk of blood clots.

How to manage the interaction:
Taking Atranza Capsule with tranexamic acid is not recommended due to its increased effects, however, it can be taken only if your doctor has advised it. If you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinAprotinin
Severe
How does the drug interact with Atranza Capsule:
Co-administration of Aprotinin and Atranza Capsule may increase the risk of blood clots.

How to manage the interaction:
Co-administration of Atranza Capsule with Aprotinin can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - chest pain, coughing up blood, sudden loss of vision, pain, redness, or swelling in your arm or leg - contact your doctor right away. Do not stop using any medications without a doctor's advice.
TretinoinItraconazole
Severe
How does the drug interact with Atranza Capsule:
The blood levels of Atranza Capsule may rise when itraconazole and Atranza Capsule are taken together, which may lead to pseudotumor cerebri(elevated pressure in the brain).

How to manage the interaction:
Atranza Capsule and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you have a headache, nausea, vomiting, blurred vision, sensitivity to light, or ringing in the ears, contact a doctor. Never stop taking a medication without consulting a doctor.
TretinoinLeflunomide
Severe
How does the drug interact with Atranza Capsule:
Co-administration of leflunomide and Atranza Capsule can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Atranza Capsule and leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinBexarotene
Severe
How does the drug interact with Atranza Capsule:
Taking Atranza Capsule with Bexarotene may increase the risk of pancreatitis (inflammation of pancreas).

How to manage the interaction:
Although there is a possible interaction between Atranza Capsule and Bexarotene, you can take these medicines together if prescribed by your doctor. If you're having symptoms like nausea, vomiting, or pain in your upper abdomen, contact your doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat 5 portions of vegetables and fruits in a day.
  • Reduce the intake of salt and fat.
  • Regular exercise may help to reduce depression and excessive tiredness after treatment.
  • Start with gentle walking and once your white blood cell count comes back to normal, you can go swimming.
  • Avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

RETINOIDS

Atranza Capsule Substitute

Substitutes safety advice

  • CA Atra 10 Softgel Capsule 100's

    by Others

    ₹78.30per tablet

  • Ematra Soft Gelatin Capsule 100's

    by AYUR

    ₹77.62per tablet

  • Ca-Astrans-10 mg Capsule 30's

    by Others

    ₹130.00per tablet

  • Atranza 10 mg Capsule 100's

    by Others

    ₹89.00per tablet

  • CA Retrans Softgel Capsule 100's

    by Others

    ₹96.35per tablet

Product Substitutes

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Aug 20, 2024 | 1:14 PM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Atranza Capsule works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

You are recommended to avoid pregnancy while taking Atranza Capsule and for 1 month after stopping treatment with Atranza Capsule as it may cause the birth of the deformed baby. Therefore, you are advised to use effective contraceptive measures while taking Atranza Capsule and for 1 month after stopping treatment with Atranza Capsule to prevent pregnancy. Also, women using Atranza Capsule should take a pregnancy test every month and if you become pregnant while taking Atranza Capsule, inform your doctor immediately.

Atranza Capsule may cause dizziness as a temporary side effect. Therefore, drive only if you are alert after taking Atranza Capsule.

You are not recommended to take low-dose progestogens (mini pill) with Atranza Capsule as their effectiveness may be reduced. However, discuss with your doctor if you have any concerns regarding this so that a different oral contraceptive may be prescribed.

Atranza Capsule may cause painful swelling in the leg in a few patients. If you experience painful swelling in your leg, difficulty breathing or sudden chest pain while taking Atranza Capsule, please inform your doctor immediately as these might be signs of a blood clot.

Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • RIFAMPICIN
  • TETRACYCLINE
  • VITAMIN A
  • KETOCONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • FLUCONAZOLE
  • DEXAMETHASONE
  • PREDNISOLONE
  • PHENOBARBITAL
  • SAQUINAVIR
  • RITONAVIR
  • DILTIAZEM
  • VERAPAMIL
  • CIMETIDINE
  • CICLOSPORIN
  • APROTININ
  • AMINOCAPROIC ACID
  • TRANEXAMIC ACID

Special Advise

Atranza Capsule may affect your mood and behaviour. Therefore, you are recommended to inform your family and friends that you are taking Atranza Capsule so that they may notice any changes and help you identify problems that are needed to be discussed with your doctor.

Disease/Condition Glossary

Acute promyelocytic leukaemia (APL): It is a blood cancer that causes a marked increase in a type of immature white blood cells known as promyelocytes in the blood and bone marrow. The symptoms of APL include blood in the urine, nosebleeds, loss of appetite, extreme tiredness, unexplained bruising or excessive bleeding from small cuts.

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