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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Online payment accepted

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Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dubinor Tablet

Dubinor Tablet is a combination medicine indicated to manage neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, and evoked pain (pain caused by events usually not painful).

Dubinor Tablet is a combination of three drugs: Methylcobalamin (vitamin), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Methylcobalamin is a vitamin that aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Dubinor Tablet helps to treat neuropathic pain.

Take Dubinor Tablet as prescribed. Based on your medical condition, your doctor will decide the dose and duration. In some cases, Dubinor Tablet may cause dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of the lower legs and hands), weight gain, and dry mouth. The majority of these side effects do not necessitate medical attention and will subside gradually over time. However, if you are experiencing these side effects regularly, you should consult your doctor.

Please do not take Dubinor Tablet if you are allergic to any of its ingredients. Consult your doctor before taking Dubinor Tablet if you are pregnant or breastfeeding. Dubinor Tablet may cause drowsiness and dizziness, so drive only if you are alert. Dubinor Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Dubinor Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Dubinor Tablet

Neuropathic pain

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Dubinor Tablet is a combination of three drugs: Methylcobalamin (a form of vitamin B), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Dubinor Tablet is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Dubinor Tablet helps to treat neuropathic pain.

Storage

Keep Dubinor Tablet out of the sight and reach of children.

Drug Warnings

If you are allergic to any of the ingredients in Dubinor Tablet , do not consume it. Please do not stop taking Dubinor Tablet without first consulting your doctor, as this may result in withdrawal symptoms. If you are pregnant or breastfeeding, do not take Dubinor Tablet unless your doctor has prescribed it. Dubinor Tablet may cause drowsiness and dizziness, therefore drive only if you are alert. Dubinor Tablet is not recommended for children as safety and effectiveness have not been established. Avoid drinking alcohol while taking Dubinor Tablet as it may cause drowsiness and sleepiness. If you have suicidal thoughts, consult your doctor right away.

Drug-Drug Interactions

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NortriptylinePotassium citrate
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Include vitamin B and D-rich foods in your diet.
  • Cayenne pepper should be included in your diet because it can help with neuropathic pain.
  • Exercising regularly helps to improve overall health and combat pain.
  • Rest well and get plenty of rest.
  • Taking a warm bath can be very relaxing.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can reduce stress, pain sensitivity and improve coping skills.
  • Acupuncture, by stimulating pressure points, can be beneficial.
  • Massages with essential oils can help increase circulation.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

FAQs

Dubinor Tablet contains Methylcobalamin, Nortriptyline, and Pregabalin. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline alters the way nerves receive pain signals, thereby decreasing pain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Dubinor Tablet helps to treat neuropathic pain.

Dubinor Tablet contains pregabalin. It may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Dry mouth could be a side-effect of Dubinor Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not stop taking Dubinor Tablet without consulting your doctor, as this could result in withdrawal symptoms. Continue taking Dubinor Tablet for as long as prescribed to treat your condition effectively. If you experience any difficulty while taking Dubinor Tablet , do not be afraid to speak with your doctor.

Dubinor Tablet is used to treat diabetic neuropathy. Diabetic neuropathy is a condition that causes nerve damage due to high blood glucose levels. It primarily affects the nerves in the legs and feet.

Dubinor Tablet may cause peripheral oedema. The swelling of the hands and lower legs are known as peripheral oedema. If you experience oedema, avoid sitting or standing for extended periods. Raise your legs by laying down and placing a pillow under them.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • CODEINE
  • HYDROCODONE
  • MORPHINE
  • OXYCODONE
  • TRAMADOL
  • ACETAMINOPHEN
  • TOPIRAMATE
  • ALPRAZOLAM
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • ONDANSETRON
  • ST JOHN'S WORT

Special Advise

Dubinor Tablet contains Nortriptyline (antidepressant), which can lead to suicidal thoughts. Suicidal thoughts or behaviour should be closely monitored in people taking Dubinor Tablet . If you have suicidal thoughts, don't be afraid to talk to your doctor right away.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also familiar with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury. The body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).

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