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  3. K-Mac Oral Solution 450 ml

K-Mac Oral Solution 450 ml, Pack of 1
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
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Whats That

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Composition :

MAGNESIUM CITRATE-375MG + POTASSIUM CITRATE-1100MG

Manufacturer/Marketer :

Fourrts India Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About K-Mac Oral Solution

K-Mac Oral Solution is indicated for the treatment of renal tubular acidosis and kidney stones due to low citric acid levels or high uric acid. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. Renal tubular acidosis is a condition in which the kidneys fail to excrete acids into the urine, this causes the blood to remain too acidic.
 
K-Mac Oral Solution is a combination of two drugs, namely: Magnesium citrate and Potassium citrate. K-Mac Oral Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation, growth and accumulation of stone-forming salts.
 
You are advised to take K-Mac Oral Solution for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as abdominal discomfort, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking K-Mac Oral Solution if you are pregnant or breastfeeding. K-Mac Oral Solution is not recommended for children as safety and effectiveness have not been established. It is not known if alcohol interacts with K-Mac Oral Solution , so please consult a doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of K-Mac Oral Solution

Kidney stones, renal tubular acidosis.

Directions for Use

Check the label for directions before use. The prescribed dose of K-Mac Oral Solution should be diluted with a glass of water and taken after meals/bedtime or as advised by the doctor.

Medicinal Benefits

K-Mac Oral Solution is a combination of two drugs, namely: Magnesium citrate and Potassium citrate. K-Mac Oral Solution is indicated for the treatment of renal tubular acidosis with calcium stones, uric acid lithiasis with or without calcium stone, hypocitraturic calcium oxalate nephrolithiasis (kidney stones). K-Mac Oral Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation, growth and accumulation of stone-forming salts. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take K-Mac Oral Solution if you are allergic to any of its components; if you have hyperkalaemia (high levels of potassium), delayed gastric emptying, intestinal obstruction, peptic ulcers, urinary tract infection, or renal insufficiency. Inform your doctor if you have gastrointestinal lesions. If you experience severe vomiting, gastrointestinal bleeding or abdominal pain, stop taking K-Mac Oral Solution and consult a doctor immediately. K-Mac Oral Solution is not recommended for children as safety and effectiveness have not been established. Consult your doctor before taking K-Mac Oral Solution if you are pregnant or breastfeeding. 

Drug-Drug Interactions

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Magnesium citrateEltrombopag
Critical
Potassium citrateTriprolidine
Critical

Drug-Drug Interactions

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Magnesium citrateEltrombopag
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking K-Mac Oral Solution 450 ml with Eltrombopag can make it less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml with Eltrombopag is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take eltrombopag on an empty stomach at least 2 hours before or 4 hours after K-Mac Oral Solution 450 ml. Do not discontinue any medication without consulting a doctor.
Potassium citrateTriprolidine
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking Triprolidine and K-Mac Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Triprolidine with K-Mac Oral Solution 450 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateHydroxyzine
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking Hydroxyzine and K-Mac Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Hydroxyzine with K-Mac Oral Solution 450 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateNortriptyline
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Coadministration of Nortriptyline with K-Mac Oral Solution 450 ml can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Nortriptyline with K-Mac Oral Solution 450 ml together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Potassium citrateProcyclidine
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking Procyclidine and K-Mac Oral Solution 450 ml together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking procyclidine with K-Mac Oral Solution 450 ml is not recommended, but it can be taken together if advised by your doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citratePromazine
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking Promazine and K-Mac Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml with Promazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateImipramine
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking Imipramine and K-Mac Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml and Imipramine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateDicyclomine
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking Dicyclomine and K-Mac Oral Solution 450 ml together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Dicyclomine with K-Mac Oral Solution 450 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateTrospium
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking K-Mac Oral Solution 450 ml and trospium together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Trospium with K-Mac Oral Solution 450 ml is not recommended as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateOlanzapine
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking Olanzapine with K-Mac Oral Solution 450 ml can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Olanzapine and K-Mac Oral Solution 450 ml is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids as they help in flushing out excess minerals.
  • Limit salt intake. High amounts of salt can increase the risk of kidney stones.
  • Maintain a healthy weight by exercising regularly.
  • Avoid foods rich in oxalates such as spinach, nuts, okra, dates, avocado, hot chocolate, cocoa, baked potato, french fries, and cereals as they might increase the risk of oxalate stones.
  • Try maintaining optimum levels of calcium in the body as too little or high calcium can lead to kidney stones.

Habit Forming

No

Therapeutic Class

RENAL AND GENITOURINARY AGENT

K-Mac Oral Solution Substitute

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:39 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

K-Mac Oral Solution contains Magnesium citrate and Potassium citrate. K-Mac Oral Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation of stone-forming salts.

To treat your condition effectually, continue taking K-Mac Oral Solution for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking K-Mac Oral Solution .

Avoid taking K-Mac Oral Solution if you have peptic ulcers as K-Mac Oral Solution has ulcerogenic potential, which could lead to further ulceration.

Diarrhoea might be a side-effect of K-Mac Oral Solution . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Consult a doctor before taking K-Mac Oral Solution if you have an active urinary tract infection, as K-Mac Oral Solution increases the urinary pH, which might promote further bacterial growth.

Drug-Drug Interactions Checker List

  • TRIAMTERENE
  • SPIRONOLACTONE
  • AMILORIDE

Disease/Condition Glossary

Kidney stones: Nephrolithiasis, also known as kidney stones, is a disease affecting the urinary tract. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. They are the common cause of blood in urine and can be painful when passing through the urinary tract. Symptoms include severe pain, usually in one side of the abdomen and nausea. 

Renal tubular acidosis: It is a condition that involves the accumulation of acid in the body due to the failure of the kidneys to acidify the urine appropriately. The kidneys fail to excrete acids into the urine, which causes the blood to remain too acidic. If not treated, it could lead to kidney stones, bone disease, kidney disease or failure.

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