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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Whats That

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Synonym :

ABIRATERONE ACETATE

Composition :

ABIRATERONE-500MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Abirapro 500Mg Tablet

Abirapro 500Mg Tablet belongs to the group of medicines called androgen biosynthesis inhibitors that is indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts.
 
Abirapro 500Mg Tablet contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.
 
In some cases, Abirapro 500Mg Tablet may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.
 
Abirapro 500Mg Tablet is not for use in women, children, and adolescents. Abirapro 500Mg Tablet should not be given in combination with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Abirapro 500Mg Tablet

Prostate cancer

Directions for Use

Take this medicine on an empty stomach, i.e., 1 hour before or 2 hours after food. Swallow Abirapro 500Mg Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Abirapro 500Mg Tablet belongs to the group of medicines called androgen biosynthesis inhibitors, indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts. Abirapro 500Mg Tablet contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is indicated in patients with metastatic castration-resistant prostate cancer (CRPC) who have received prior chemotherapy containing docetaxel and metastatic high-risk castration-sensitive prostate cancer (CSPC). Abirapro 500Mg Tablet is prescribed in the early stages of the disease, where it is still responding to hormone therapy. It is used with androgen deprivation therapy (a treatment that lowers testosterone).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Abirapro 500Mg Tablet

  • Diarrhoea
  • Low blood potassium
  • High blood pressure
  • Urinary tract infection
  • Oedema (fluid in legs or feet)

Drug Warnings

Do not take Abirapro 500Mg Tablet if you are allergic to any of its components, if you have severe liver damage, or in combination with Ra-233 (used to treat prostate cancer). Inform your doctor if you have liver problems, high blood pressure, low blood potassium, heart failure, heart or blood vessel problems, irregular or rapid heartbeat, heart rhythm problems, shortness of breath, rapid weight gain, swelling in the legs, ankles, or feet, high blood sugar, bone problems, or if you have taken ketoconazole in the past for prostate cancer. Abirapro 500Mg Tablet may cause libido (decreased sex drive), muscle weakness, decreased red blood cells, and/or muscle pain. Abirapro 500Mg Tablet should not be given in combination with Ra-233 due to an increased risk of bone fracture or death.

Drug-Drug Interactions

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AbirateroneThioridazine
Critical
AbirateroneMesoridazine
Critical

Drug-Drug Interactions

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AbirateroneThioridazine
Critical
How does the drug interact with Abirapro 500Mg Tablet:
Taking Abirapro 500Mg Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirapro 500Mg Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Abirapro 500Mg Tablet:
Taking Abirapro 500Mg Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Abirapro 500Mg Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Abirapro 500Mg Tablet:
Coadministration of Abirapro 500Mg Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Abirapro 500Mg Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Abirapro 500Mg Tablet:
Taking Abirapro 500Mg Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirapro 500Mg Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneZiprasidone
Critical
How does the drug interact with Abirapro 500Mg Tablet:
Taking Abirapro 500Mg Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Abirapro 500Mg Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneEdoxaban
Severe
How does the drug interact with Abirapro 500Mg Tablet:
Coadministration of Abirapro 500Mg Tablet with Edoxaban can increase the levels of Edoxaban in the body. This increases the risk or severity of side effects like serious bleeding complications.

How to manage the interaction:
Taking Abirapro 500Mg Tablet with Edoxaban together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting blood that looks like coffee grounds; severe headache; and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneVenetoclax
Severe
How does the drug interact with Abirapro 500Mg Tablet:
Coadministration of Abirapro 500Mg Tablet with Venetoclax can increase the levels of Venetoclax in the body. This increases the risk or severity of side effects like bleeding problems, kidney injury, and the risk of developing serious infections.

How to manage the interaction:
Taking Abirapro 500Mg Tablet with Venetoclax together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateronePrimidone
Severe
How does the drug interact with Abirapro 500Mg Tablet:
Taking Abirapro 500Mg Tablet with primidone can significantly reduce the blood levels of Abirapro 500Mg Tablet, which may lower the treatment outcomes.

How to manage the interaction:
Taking Abirapro 500Mg Tablet with Primidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience shortness of breath, chest pain or tightness, rapid heartbeat, bloating or swelling of the face, arms, hands, lower legs, or feet, low urine output, or blurred vision, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneOxycodone
Severe
How does the drug interact with Abirapro 500Mg Tablet:
Coadministration of Abirapro 500Mg Tablet with Oxycodone can increase the levels of Oxycodone in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Abirapro 500Mg Tablet with Oxycodone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, fainting, confusion, excessive drowsiness, slow heart rate, and/or shallow or difficult breathing, contact a doctor immediately. Avoid activities requiring mental alertness such as driving or operating hazardous machinery while taking these medications. Do not discontinue any medications without consulting a doctor.
AbirateronePanobinostat
Severe
How does the drug interact with Abirapro 500Mg Tablet:
Using Panobinostat together with Abirapro 500Mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Abirapro 500Mg Tablet and Panobinostat, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: an irregular heart rhythm, a heart condition, congenital long qt syndrome, conduction abnormalities, severe or prolonged diarrhea, vomiting, complications, sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Abirapro 500Mg Tablet Substitute

Substitutes safety advice
  • Samtica 500 mg Tablet 60's

    by Others

    423.67per tablet
  • Abiratred Tablet 60's

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    191.33per tablet
  • Abiratred 500 mg Tablet 20's

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    299.95per tablet
  • Abstet 500 mg Tablet 60's

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    503.33per tablet
  • Avirat Tablet 60's

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    650.00per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Abirapro 500Mg Tablet works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

Prednisolone/prednisone is prescribed along with Abirapro 500Mg Tablet to lower the chances of getting high blood pressure, fluid retention (having too much water in the body), or low blood potassium levels.

Abirapro 500Mg Tablet should not be given along with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. If you are prescribed to take Ra-233 following treatment with Abirapro 500Mg Tablet and prednisolone/prednisone, you must wait five days before starting treatment with Ra-233.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • METHADONE
  • MOXIFLOXACIN
  • ST JOHN'S WORT

Special Advise

  • Abirapro 500Mg Tablet may affect the liver. Therefore your doctor may advise regular blood tests to check for any effects on the liver.
  • Tell your doctor if you experience darkening of the urine, yellowing of the skin or eyes, or severe vomiting or nausea, as these could be signs of liver problems.
  • Abirapro 500Mg Tablet may cause low blood potassium. Stop taking Abirapro 500Mg Tablet and consult a doctor immediately if you experience muscle twitches, muscle weakness, or palpitations (pounding heartbeat).
  • Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Disease/Condition Glossary

Prostate cancer: Prostate cancer, also called prostatic carcinoma, is cancer in the prostate gland (a gland that produces seminal fluid). Symptoms include difficulty with urination, weak or interrupted flow of urine, trouble emptying the bladder completely, and pain or burning during urination.

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