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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym

ABIRATERONE ACETATE

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Alkeprost 500 mg Tablet 60's

Alkeprost 500 mg Tablet 60's belongs to the group of medicines called androgen biosynthesis inhibitors that is indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts.
 
Alkeprost 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.
 
In some cases, Alkeprost 500 mg Tablet 60's may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.
 
Alkeprost 500 mg Tablet 60's is not for use in women, children, and adolescents. Alkeprost 500 mg Tablet 60's should not be given in combination with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Alkeprost 500 mg Tablet 60's

Prostate cancer

Directions for Use

Take this medicine on an empty stomach, i.e., 1 hour before or 2 hours after food. Swallow Alkeprost 500 mg Tablet 60's as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Alkeprost 500 mg Tablet 60's belongs to the group of medicines called androgen biosynthesis inhibitors, indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts. Alkeprost 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is indicated in patients with metastatic castration-resistant prostate cancer (CRPC) who have received prior chemotherapy containing docetaxel and metastatic high-risk castration-sensitive prostate cancer (CSPC). Alkeprost 500 mg Tablet 60's is prescribed in the early stages of the disease, where it is still responding to hormone therapy. It is used with androgen deprivation therapy (a treatment that lowers testosterone).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alkeprost 500 mg Tablet 60's

  • Diarrhoea
  • Low blood potassium
  • High blood pressure
  • Urinary tract infection
  • Oedema (fluid in legs or feet)

Drug Warnings

Do not take Alkeprost 500 mg Tablet 60's if you are allergic to any of its components, if you have severe liver damage, or in combination with Ra-233 (used to treat prostate cancer). Inform your doctor if you have liver problems, high blood pressure, low blood potassium, heart failure, heart or blood vessel problems, irregular or rapid heartbeat, heart rhythm problems, shortness of breath, rapid weight gain, swelling in the legs, ankles, or feet, high blood sugar, bone problems, or if you have taken ketoconazole in the past for prostate cancer. Alkeprost 500 mg Tablet 60's may cause libido (decreased sex drive), muscle weakness, decreased red blood cells, and/or muscle pain. Alkeprost 500 mg Tablet 60's should not be given in combination with Ra-233 due to an increased risk of bone fracture or death.

Drug-Drug Interactions

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AbirateroneSaquinavir
Critical
AbirateroneThioridazine
Critical

Drug-Drug Interactions

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AbirateroneSaquinavir
Critical
How does the drug interact with Alkeprost 500 mg Tablet:
Taking Alkeprost 500 mg Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Alkeprost 500 mg Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneThioridazine
Critical
How does the drug interact with Alkeprost 500 mg Tablet:
Taking Alkeprost 500 mg Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Alkeprost 500 mg Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneZiprasidone
Critical
How does the drug interact with Alkeprost 500 mg Tablet:
Taking Alkeprost 500 mg Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Alkeprost 500 mg Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Alkeprost 500 mg Tablet:
Coadministration of Alkeprost 500 mg Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Alkeprost 500 mg Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Alkeprost 500 mg Tablet:
Taking Alkeprost 500 mg Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Alkeprost 500 mg Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneQuinidine
Severe
How does the drug interact with Alkeprost 500 mg Tablet:
Taking Alkeprost 500 mg Tablet with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Alkeprost 500 mg Tablet with Quinidine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneEdoxaban
Severe
How does the drug interact with Alkeprost 500 mg Tablet:
Coadministration of Alkeprost 500 mg Tablet with Edoxaban can increase the levels of Edoxaban in the body. This increases the risk or severity of side effects like serious bleeding complications.

How to manage the interaction:
Taking Alkeprost 500 mg Tablet with Edoxaban together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting blood that looks like coffee grounds; severe headache; and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateronePasireotide
Severe
How does the drug interact with Alkeprost 500 mg Tablet:
Taking Alkeprost 500 mg Tablet with Pasireotide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Alkeprost 500 mg Tablet with Pasireotide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneCeritinib
Severe
How does the drug interact with Alkeprost 500 mg Tablet:
Taking Alkeprost 500 mg Tablet with Ceritinib can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Alkeprost 500 mg Tablet with Ceritinib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneLeflunomide
Severe
How does the drug interact with Alkeprost 500 mg Tablet:
Coadministration of Alkeprost 500 mg Tablet with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Alkeprost 500 mg Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Alkeprost 500 mg Tablet 60's Substitute

Substitutes safety advice
  • Abiratred Tablet 60's

    by Others

    191.33per tablet
  • Zecyte 500Mg Tablet 60'S

    by AYUR

    266.50per tablet
  • Zabpro 500Mg Tablet 60'S

    by AYUR

    328.00per tablet
  • Abione-500Mg Tablet 60'S

    by AYUR

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  • Abirapro 500Mg Tablet 60'S

    by AYUR

    382.67per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • METHADONE
  • MOXIFLOXACIN
  • ST JOHN'S WORT

Special Advise

  • Alkeprost 500 mg Tablet 60's may affect the liver. Therefore your doctor may advise regular blood tests to check for any effects on the liver.
  • Tell your doctor if you experience darkening of the urine, yellowing of the skin or eyes, or severe vomiting or nausea, as these could be signs of liver problems.
  • Alkeprost 500 mg Tablet 60's may cause low blood potassium. Stop taking Alkeprost 500 mg Tablet 60's and consult a doctor immediately if you experience muscle twitches, muscle weakness, or palpitations (pounding heartbeat).
  • Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Disease/Condition Glossary

Prostate cancer: Prostate cancer, also called prostatic carcinoma, is cancer in the prostate gland (a gland that produces seminal fluid). Symptoms include difficulty with urination, weak or interrupted flow of urine, trouble emptying the bladder completely, and pain or burning during urination.

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