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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Abiratas Tablet

Abiratas Tablet belongs to the group of medicines called androgen biosynthesis inhibitors that is indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts.
 
Abiratas Tablet contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.
 
In some cases, Abiratas Tablet may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.
 
Abiratas Tablet is not for use in women, children, and adolescents. Abiratas Tablet should not be given in combination with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

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Whats That

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Non returnable*
COD available

Online payment accepted

Synonym

ABIRATERONE ACETATE

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Jul-2024

for this medicine

Uses of Abiratas Tablet

Prostate cancer

Medicinal Benefits

Abiratas Tablet belongs to the group of medicines called androgen biosynthesis inhibitors, indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts. Abiratas Tablet contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is indicated in patients with metastatic castration-resistant prostate cancer (CRPC) who have received prior chemotherapy containing docetaxel and metastatic high-risk castration-sensitive prostate cancer (CSPC). Abiratas Tablet is prescribed in the early stages of the disease, where it is still responding to hormone therapy. It is used with androgen deprivation therapy (a treatment that lowers testosterone).

Side Effects of Abiratas Tablet

  • Diarrhoea
  • Low blood potassium
  • High blood pressure
  • Urinary tract infection
  • Oedema (fluid in legs or feet)

Directions for Use

Take this medicine on an empty stomach, i.e., 1 hour before or 2 hours after food. Swallow Abiratas Tablet as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Abiratas Tablet if you are allergic to any of its components, if you have severe liver damage, or in combination with Ra-233 (used to treat prostate cancer). Inform your doctor if you have liver problems, high blood pressure, low blood potassium, heart failure, heart or blood vessel problems, irregular or rapid heartbeat, heart rhythm problems, shortness of breath, rapid weight gain, swelling in the legs, ankles, or feet, high blood sugar, bone problems, or if you have taken ketoconazole in the past for prostate cancer. Abiratas Tablet may cause libido (decreased sex drive), muscle weakness, decreased red blood cells, and/or muscle pain. Abiratas Tablet should not be given in combination with Ra-233 due to an increased risk of bone fracture or death.

Therapeutic Class

MISCELLANEOUS

Drug-Drug Interactions

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AbirateroneZiprasidone
Critical
AbirateroneSaquinavir
Critical

Drug-Drug Interactions

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AbirateroneZiprasidone
Critical
How does the drug interact with Abiratas Tablet:
Taking Abiratas Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Abiratas Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Abiratas Tablet:
Taking Abiratas Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abiratas Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Abiratas Tablet:
Taking Abiratas Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Abiratas Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneThioridazine
Critical
How does the drug interact with Abiratas Tablet:
Taking Abiratas Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abiratas Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Abiratas Tablet:
Coadministration of Abiratas Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Abiratas Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneToremifene
Severe
How does the drug interact with Abiratas Tablet:
Taking Abiratas Tablet with Toremifene can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Abiratas Tablet with Toremifene together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneVandetanib
Severe
How does the drug interact with Abiratas Tablet:
Taking Abiratas Tablet with Vandetanib can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abiratas Tablet with Vandetanib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneDroperidol
Severe
How does the drug interact with Abiratas Tablet:
Using Droperidol together with Abiratas Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Abiratas Tablet and Droperidol together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: an irregular heart rhythm, a heart condition, problems with your heart's electrical system, severe or long-lasting diarrhea or vomiting, complications, sudden dizziness or lightheadedness, fainting, difficulty breathing, heart palpitations, weakness, feeling sleepy or confused, muscle pain, or feeling nauseous or vomiting. Do not stop using any medications without talking to a doctor.
AbirateroneLoperamide
Severe
How does the drug interact with Abiratas Tablet:
When taken in combination, Abiratas Tablet may considerably raise loperamide levels in the blood and cause irregular heart rhythm.

How to manage the interaction:
Although taking loperamide with Abiratas Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
AbirateroneEdoxaban
Severe
How does the drug interact with Abiratas Tablet:
Coadministration of Abiratas Tablet with Edoxaban can increase the levels of Edoxaban in the body. This increases the risk or severity of side effects like serious bleeding complications.

How to manage the interaction:
Taking Abiratas Tablet with Edoxaban together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting blood that looks like coffee grounds; severe headache; and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • METHADONE
  • MOXIFLOXACIN
  • ST JOHN'S WORT

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Special Advise

  • Abiratas Tablet may affect the liver. Therefore your doctor may advise regular blood tests to check for any effects on the liver.
  • Tell your doctor if you experience darkening of the urine, yellowing of the skin or eyes, or severe vomiting or nausea, as these could be signs of liver problems.
  • Abiratas Tablet may cause low blood potassium. Stop taking Abiratas Tablet and consult a doctor immediately if you experience muscle twitches, muscle weakness, or palpitations (pounding heartbeat).
  • Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Disease/Condition Glossary

Prostate cancer: Prostate cancer, also called prostatic carcinoma, is cancer in the prostate gland (a gland that produces seminal fluid). Symptoms include difficulty with urination, weak or interrupted flow of urine, trouble emptying the bladder completely, and pain or burning during urination.

Abiratas Tablet Substitute

Substitutes safety advice
  • Zybiraa 250Mg Tablet 120'S

    by AYUR

    150.26per tablet
  • Abione 250Mg Tablet 120'S

    by AYUR

    206.32per tablet
  • Abtmed 250 mg Tablet 120's

    184.50per tablet
  • Abitate U 250mg Tablet 120's

    205.00per tablet
  • Inveteron 250 mg Tablet 30's

    270.55per tablet
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