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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym

ABIRATERONE ACETATE

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Zybiraa 250Mg Tablet 120'S

Zybiraa 250Mg Tablet 120'S belongs to the group of medicines called androgen biosynthesis inhibitors that is indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts.
 
Zybiraa 250Mg Tablet 120'S contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.
 
In some cases, Zybiraa 250Mg Tablet 120'S may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.
 
Zybiraa 250Mg Tablet 120'S is not for use in women, children, and adolescents. Zybiraa 250Mg Tablet 120'S should not be given in combination with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Zybiraa 250Mg Tablet 120'S

Prostate cancer

Directions for Use

Take this medicine on an empty stomach, i.e., 1 hour before or 2 hours after food. Swallow Zybiraa 250Mg Tablet 120'S as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Zybiraa 250Mg Tablet 120'S belongs to the group of medicines called androgen biosynthesis inhibitors, indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts. Zybiraa 250Mg Tablet 120'S contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is indicated in patients with metastatic castration-resistant prostate cancer (CRPC) who have received prior chemotherapy containing docetaxel and metastatic high-risk castration-sensitive prostate cancer (CSPC). Zybiraa 250Mg Tablet 120'S is prescribed in the early stages of the disease, where it is still responding to hormone therapy. It is used with androgen deprivation therapy (a treatment that lowers testosterone).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zybiraa 250Mg Tablet 120'S

  • Diarrhoea
  • Low blood potassium
  • High blood pressure
  • Urinary tract infection
  • Oedema (fluid in legs or feet)

Drug Warnings

Do not take Zybiraa 250Mg Tablet 120'S if you are allergic to any of its components, if you have severe liver damage, or in combination with Ra-233 (used to treat prostate cancer). Inform your doctor if you have liver problems, high blood pressure, low blood potassium, heart failure, heart or blood vessel problems, irregular or rapid heartbeat, heart rhythm problems, shortness of breath, rapid weight gain, swelling in the legs, ankles, or feet, high blood sugar, bone problems, or if you have taken ketoconazole in the past for prostate cancer. Zybiraa 250Mg Tablet 120'S may cause libido (decreased sex drive), muscle weakness, decreased red blood cells, and/or muscle pain. Zybiraa 250Mg Tablet 120'S should not be given in combination with Ra-233 due to an increased risk of bone fracture or death.

Drug-Drug Interactions

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AbirateroneEliglustat
Critical
AbirateroneSaquinavir
Critical

Drug-Drug Interactions

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AbirateroneEliglustat
Critical
How does the drug interact with Zybiraa 250Mg Tablet:
Coadministration of Zybiraa 250Mg Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Zybiraa 250Mg Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Zybiraa 250Mg Tablet:
Taking Zybiraa 250Mg Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zybiraa 250Mg Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneZiprasidone
Critical
How does the drug interact with Zybiraa 250Mg Tablet:
Taking Zybiraa 250Mg Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Zybiraa 250Mg Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneThioridazine
Critical
How does the drug interact with Zybiraa 250Mg Tablet:
Taking Zybiraa 250Mg Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zybiraa 250Mg Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Zybiraa 250Mg Tablet:
Taking Zybiraa 250Mg Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Zybiraa 250Mg Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneVenetoclax
Severe
How does the drug interact with Zybiraa 250Mg Tablet:
Coadministration of Zybiraa 250Mg Tablet with Venetoclax can increase the levels of Venetoclax in the body. This increases the risk or severity of side effects like bleeding problems, kidney injury, and the risk of developing serious infections.

How to manage the interaction:
Taking Zybiraa 250Mg Tablet with Venetoclax together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneHydroxychloroquine
Severe
How does the drug interact with Zybiraa 250Mg Tablet:
The combined use of Zybiraa 250Mg Tablet and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Zybiraa 250Mg Tablet and Hydroxychloroquine can lead to an interaction, but it can be taken if your doctor advises. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
AbirateronePasireotide
Severe
How does the drug interact with Zybiraa 250Mg Tablet:
Taking Zybiraa 250Mg Tablet with Pasireotide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zybiraa 250Mg Tablet with Pasireotide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneOsimertinib
Severe
How does the drug interact with Zybiraa 250Mg Tablet:
Taking Zybiraa 250Mg Tablet with Osimertinib can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zybiraa 250Mg Tablet with Osimertinib together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneMethadone
Severe
How does the drug interact with Zybiraa 250Mg Tablet:
Taking Zybiraa 250Mg Tablet with Methadone can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zybiraa 250Mg Tablet and Methadone together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Zybiraa 250Mg Tablet 120'S Substitute

Substitutes safety advice
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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • METHADONE
  • MOXIFLOXACIN
  • ST JOHN'S WORT

Special Advise

  • Zybiraa 250Mg Tablet 120'S may affect the liver. Therefore your doctor may advise regular blood tests to check for any effects on the liver.
  • Tell your doctor if you experience darkening of the urine, yellowing of the skin or eyes, or severe vomiting or nausea, as these could be signs of liver problems.
  • Zybiraa 250Mg Tablet 120'S may cause low blood potassium. Stop taking Zybiraa 250Mg Tablet 120'S and consult a doctor immediately if you experience muscle twitches, muscle weakness, or palpitations (pounding heartbeat).
  • Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Disease/Condition Glossary

Prostate cancer: Prostate cancer, also called prostatic carcinoma, is cancer in the prostate gland (a gland that produces seminal fluid). Symptoms include difficulty with urination, weak or interrupted flow of urine, trouble emptying the bladder completely, and pain or burning during urination.

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