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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Whats That

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in last 7 days

Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Aldonil Plus Tablet

Aldonil Plus Tablet is a combination medicine indicated for the management of diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It primarily damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type 1 and type 2 diabetes.
 
Aldonil Plus Tablet contains Epalrestat and Methylcobalamin. Epalrestat works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol, thereby preventing the accumulation of sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients suffering from diabetes which leads to nerve pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Together, Aldonil Plus Tablet helps in treating diabetic neuropathy.
 
You are advised to take Aldonil Plus Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Aldonil Plus Tablet may cause drowsiness and dizziness, so drive only if you are alert. Aldonil Plus Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Aldonil Plus Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Aldonil Plus Tablet

Diabetic neuropathy (diabetic nerve pain)

Directions for Use

Swallow Aldonil Plus Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Aldonil Plus Tablet is a combination of two drugs, namely: Epalrestat and Methylcobalamin. Aldonil Plus Tablet is indicated for the management of diabetic neuropathy. Epalrestat works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. This prevents the accumulation of sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients suffering from diabetes which leads to nerve pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Together, Aldonil Plus Tablet helps in treating diabetic neuropathy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aldonil Plus Tablet

  • Dizziness
  • Nausea
  • Vomiting
  • Headache
  • Diarrhoea

Drug Warnings

Do not take Aldonil Plus Tablet if you are allergic to any of its components. Inform your doctor if you have liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Aldonil Plus Tablet may cause drowsiness and dizziness, so drive only if you are alert. Aldonil Plus Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Aldonil Plus Tablet as it could lead to increased drowsiness and sleepiness. 

Drug-Drug Interactions

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MecobalaminChloramphenicol
Moderate
MecobalaminNeomycin
Moderate

Drug-Drug Interactions

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MecobalaminChloramphenicol
Moderate
How does the drug interact with Aldonil Plus Tablet:
Coadministration of Aldonil Plus Tablet with Chloramphenicol can impair absorption and increase the levels of Aldonil Plus Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Aldonil Plus Tablet with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
MecobalaminNeomycin
Moderate
How does the drug interact with Aldonil Plus Tablet:
Coadministration of Aldonil Plus Tablet with Neomycin can impair the absorption of Aldonil Plus Tablet and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Aldonil Plus Tablet with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Aldonil Plus Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CHLORAMPHENICOL
  • METFORMIN

Disease/Condition Glossary

Diabetic neuropathy: Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type1 and type2 diabetes, which usually develops slowly. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty with coordination when walking, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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