Alrista Plus Tablet 10's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Sureshvarma D , MPharma

MRP ₹250.5

(Inclusive of all Taxes)

₹37.6 Cashback (15%)

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Non returnable*

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Prescription drug

Whats That

About Alrista Plus Tablet

Alrista Plus Tablet is a combination medicine indicated for the management of diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It primarily damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type 1 and type 2 diabetes.

Alrista Plus Tablet contains Epalrestat and Methylcobalamin. Epalrestat works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol, thereby preventing the accumulation of sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients suffering from diabetes which leads to nerve pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Together, Alrista Plus Tablet helps in treating diabetic neuropathy.

You are advised to take Alrista Plus Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Alrista Plus Tablet may cause drowsiness and dizziness, so drive only if you are alert. Alrista Plus Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Alrista Plus Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Alrista Plus Tablet

Diabetic neuropathy (diabetic nerve pain)

Directions for Use

Swallow Alrista Plus Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Alrista Plus Tablet is a combination of two drugs, namely: Epalrestat and Methylcobalamin. Alrista Plus Tablet is indicated for the management of diabetic neuropathy. Epalrestat works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. This prevents the accumulation of sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients suffering from diabetes which leads to nerve pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Together, Alrista Plus Tablet helps in treating diabetic neuropathy.

Storage

Keep Alrista Plus Tablet out of reach and sight of children.

Side effects of Alrista Plus Tablet

Irregular Heart Beat

Eat potassium-rich foods like avocados, bananas, spinach, and potatoes.
Stay hydrated by drinking plenty of water.
Exercise regularly and maintain healthy weight.
Manage stress.
Prioritize 7-9 hours of sleep each night to help your body and mind recharge.
Avoid smoking and limit intake of caffeine.
Practice stress-reducing activities like meditation, yoga, or deep breathing to help calm your mind and body.
Avoid stimulants and illegal drugs.
Call your doctor if it worsens.

Rash

Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
Protect your skin from extreme heat and try to apply wet compresses.
Soak in the cool bath, which gives a soothing impact to the affected area.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Stomach Ache

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Drug Warnings

Do not take Alrista Plus Tablet if you are allergic to any of its components. Inform your doctor if you have liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Alrista Plus Tablet may cause drowsiness and dizziness, so drive only if you are alert. Alrista Plus Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Alrista Plus Tablet as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions

MecobalaminNeomycin

Moderate

MecobalaminChloramphenicol

Moderate

Drug-Drug Interactions

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MecobalaminNeomycin

Moderate

How does the drug interact with Alrista Plus Tablet:
Coadministration of Alrista Plus Tablet with Neomycin can impair the absorption of Alrista Plus Tablet and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Alrista Plus Tablet with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

MecobalaminChloramphenicol

Moderate

How does the drug interact with Alrista Plus Tablet:
Coadministration of Alrista Plus Tablet with Chloramphenicol can impair absorption and increase the levels of Alrista Plus Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Alrista Plus Tablet with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Include food rich in vitamin B and D in your diet.
Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
Exercising regularly helps in improving overall health and combating pain.
Rest well, get plenty of sleep.
Try taking a warm bath as it can be soothing.
Avoid smoking and alcohol consumption.
Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
Acupuncture can be helpful by stimulating pressure points.
Using essential oils for massages can help increase circulation.

Side Effects of Alrista Plus Tablet

Dizziness
Nausea
Vomiting
Headache
Diarrhoea

Habit Forming

No

Therapeutic Class

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:39 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Alrista Plus Tablet work?

Alrista Plus Tablet is a combination of two drugs, namely: Epalrestat and Methylcobalamin. Epalrestat prevents the accumulation of sorbitol by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Together, Alrista Plus Tablet helps in treating diabetic neuropathy.

Does Alrista Plus Tablet cause diarrhoea?

Diarrhoea could be a side-effect of Alrista Plus Tablet . Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.

What conditions should I inform the doctor?

Inform your doctor if you notice any cut/sore on your feet that is not healing or if you have a tingling/burning sensation in your feet/arms causing a hamper to the daily routine. If you experience trouble in sexual function, digestion, or urination, please consult a doctor. Examine your feet daily for lesions and wear proper footwear to prevent diabetic neuropathy.

Can I stop taking Alrista Plus Tablet if I feel well?

Do not discontinue Alrista Plus Tablet without consulting your doctor. To treat your condition effectually, continue taking Alrista Plus Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Alrista Plus Tablet .

Does Alrista Plus Tablet cause oedema?

Alrista Plus Tablet may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

Does Alrista Plus Tablet help in controlling diabetes?

Alrista Plus Tablet does not help in controlling diabetes. Alrista Plus Tablet is indicated to treat neuropathic pain. It is recommended to adhere to your diabetic medicines to keep your blood sugar levels at normal.

Drug-Drug Interactions Checker List

CHLORAMPHENICOL
METFORMIN

Disease/Condition Glossary

Diabetic neuropathy: Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type1 and type2 diabetes, which usually develops slowly. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty with coordination when walking, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).