Amlosafe MT 50 Tablet 10's

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Reviewed By Hari Kumar , MBBS

MRP ₹98.5

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Whats That

About Amlosafe MT 50 Tablet

Amlosafe MT 50 Tablet belongs to the group of antihypertensive agents used to treat high blood pressure/hypertension and angina pectoris. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Angina is basically a pain in the heart and chest.

Amlosafe MT 50 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Amlosafe MT 50 Tablet helps treat high blood pressure.

Take Amlosafe MT 50 Tablet as prescribed. In some cases, Amlosafe MT 50 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Keep your doctor informed in case you are due to undergo any surgery or dental procedure. Avoid consuming alcohol with Amlosafe MT 50 Tablet as there may be an interaction. Amlosafe MT 50 Tablet may cause dizziness, therefore, drive only if you are alert.

Uses of Amlosafe MT 50 Tablet

Hypertension, Angina pectoris

Directions for Use

Take Amlosafe MT 50 Tablet with or without food as directed by the physician. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Amlosafe MT 50 Tablet is a combination antihypertensive medication containing Metoprolol succinate and Amlodipine. It is used primarily to treat hypertension and to relax the blood vessels for seamless flow of blood. Metoprolol succinate is a beta-blocker that eases the symptoms of hypertension by blocking catecholamines that lead to increased pressure and heart rate. Amlodipine is a calcium channel blocker that decreases blood pressure by preventing the influx of calcium ions into cells and by enlarging and relaxing arteries. In addition, Amlosafe MT 50 Tablet also reduces the oxygen demands of the heart, relaxing the heart and blood vessels and requiring the heart to do less work.

Storage

Keep Amlosafe MT 50 Tablet out of the sight and reach of children.

Side effects of Amlosafe MT 50 Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Swelling

Reduce salt intake to minimize fluid buildup.
Use compression stockings, sleeves, or gloves.
Gently massage the affected area towards the heart.
Protect the swollen area from injury and keep it clean.
Use lotion or cream to keep the skin moisturized.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Reddening Of The Face

Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Rapid Or Irregular Heart Rate

Avoid triggers like alcohol, caffeine, and energy drinks.
Try relaxation techniques such as yoga, meditation, or deep breathing.
Exercise regularly as it helps maintain heart health.
Follow a nutritious and balanced diet.

Tiredness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Depression

Managing depression as a side effect of medication: a comprehensive guide.

Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
Tell your doctor about your depression symptoms to adjust medication.
Consult a therapist or counsel for emotional support.
Engage in regular exercise to release endorphins (neurotransmitters).
Practice stress-reducing techniques like meditation and deep breathing.
Build a support network of friends, family, and support groups.
Establish a consistent sleep schedule.
Eat a nutritious diet rich in fruits, vegetables, and whole grains.
Limit or avoid alcohol and recreational substances.
Keep a mood journal to track symptoms and progress.

Drug Warnings

Amlosafe MT 50 Tablet should not be used in case of any known allergy to either of the components. Amlosafe MT 50 Tablet should be used with caution in case of high risk or previous history of any arterial or thrombotic disorders, shock, cardiovascular health disorders, diabetes, heart failure, or any disease-causing psoriasis. Please inform your doctor in case of any history of an overactive thyroid, asthma, phaeochromocytoma (high BP due to a tumour in the adrenal glands), myasthenia gravis (neuromuscular disorder), COPD, heart block, liver disease or renal disease. Consult your doctor before using Amlosafe MT 50 Tablet during pregnancy or breastfeeding. Keep your doctor informed in case you are waiting to undergo any surgery or dental procedure. Amlosafe MT 50 Tablet may interact with alcohol, please consult your doctor before use. Amlosafe MT 50 Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert.

Drug-Drug Interactions

AmlodipineDantrolene

Critical

AmlodipineRifapentine

Severe

Drug-Drug Interactions

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AmlodipineDantrolene

Critical

How does the drug interact with Amlosafe MT 50 Tablet:
Using Amlosafe MT 50 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amlosafe MT 50 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.

AmlodipineRifapentine

Severe

How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Amlosafe MT 50 Tablet and Rifapentine may significantly reduce the blood levels of Amlosafe MT 50 Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Amlosafe MT 50 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

AmlodipineCarbamazepine

Severe

How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Amlosafe MT 50 Tablet and carbamazepine together may significantly reduce Amlosafe MT 50 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlosafe MT 50 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.

AmlodipineFosphenytoin

Severe

How does the drug interact with Amlosafe MT 50 Tablet:
When Amlosafe MT 50 Tablet is taken with Fosphenytoin, it may decrease the blood levels of Amlosafe MT 50 Tablet, which may make Amlosafe MT 50 Tablet less effective.

How to manage the interaction:
Although taking Amlosafe MT 50 Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

AmlodipinePhenobarbital

Severe

How does the drug interact with Amlosafe MT 50 Tablet:
Using phenobarbital and Amlosafe MT 50 Tablet may drastically lower Amlosafe MT 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Amlosafe MT 50 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

AmlodipineRifampicin

Severe

How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Amlosafe MT 50 Tablet and rifampicin together may lower Amlosafe MT 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlosafe MT 50 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

AmlodipinePhenytoin

Severe

How does the drug interact with Amlosafe MT 50 Tablet:
Using Amlosafe MT 50 Tablet and phenytoin together may drastically lower Amlosafe MT 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Amlosafe MT 50 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

AmlodipineSimvastatin

Severe

How does the drug interact with Amlosafe MT 50 Tablet:
Taking simvastatin with Amlosafe MT 50 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Amlosafe MT 50 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.

AmlodipineNitisinone

Severe

How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Amlosafe MT 50 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Amlosafe MT 50 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.

AmlodipineTizanidine

Severe

How does the drug interact with Amlosafe MT 50 Tablet:
Co-administration of Tizanidine and Amlosafe MT 50 Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Amlosafe MT 50 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits

Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits

Moderate

Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

Limit the intake of salt in your diet.
Cut back on foods that are high in fat and cholesterol.
Eat more fruits, vegetables and whole-grain foods.
Avoid taking Amlosafe MT 50 Tablet with grapefruit juice as there may be an interaction.
Avoid tobacco use. Inform your doctor in case of marijuana use.
Dress warmly, as Amlosafe MT 50 Tablet may cause cold extremities.

Side Effects of Amlosafe MT 50 Tablet

Tiredness
Dizziness
Headache
Ankle swelling
Slow heart rate
Stomach pain
Shortness of breath
Rash or itch
Cold hands and feet

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Amlosafe MT 50 Tablet work?

Amlosafe MT 50 Tablet works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.

Can I stop taking Amlosafe MT 50 Tablet on my own?

Do not stop taking Amlosafe MT 50 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Amlosafe MT 50 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Amlosafe MT 50 Tablet .

I suffer from low blood sodium levels from time to time. Can I take Amlosafe MT 50 Tablet ?

Hyponatremia (a term for low blood sodium levels) often results in lowering blood pressure and falls. One of the not so common side-effects of Amlosafe MT 50 Tablet is dizziness and lowered BP. Hence, it is best to consult your physician before taking Amlosafe MT 50 Tablet if you suffer from this condition.

Does Amlosafe MT 50 Tablet cause light-headedness?

Light-headedness could be a side-effect of Amlosafe MT 50 Tablet . It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Amlosafe MT 50 Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Can Amlosafe MT 50 Tablet affect my ability to get pregnant?

Amlosafe MT 50 Tablet is not known to affect fertility. However, not enough literature and studies exist to ascertain the effect of Amlosafe MT 50 Tablet on fertility. Please consult your doctor in case of any concerns.

Drug-Drug Interactions Checker List

QUINIDINE
PROPAFENONE
FLUOXETINE
PAROXETINE
DILTIAZEM
CLONIDINE
VERAPAMIL
ERYTHROMYCIN
KETOCONAZOLE
ITRACONAZOLE
RITONAVIR
DIGITALIS

Special Advise

In case you miss a dose of Amlosafe MT 50 Tablet , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule. Do not ever take a double dose.
If you accidentally take an extra dose of Amlosafe MT 50 Tablet , please inform your doctor immediately. Some of the common symptoms of an overdose can be low blood pressure, slow pulse rate, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin.
Do not discontinue taking Amlosafe MT 50 Tablet abruptly or without the advice of the physician.
Please know that your doctor may order blood tests to check your tolerance and need of Amlosafe MT 50 Tablet .
Amlosafe MT 50 Tablet should be used with caution in case of those over 80 or under 40 years of age.

Disease/Condition Glossary

Hypertension: Hypertension is defined as a condition in which the blood pressure remains high persistently. Normal BP is marked at 120/80 mmHg. Hypertension is defined as consistent blood pressure over 140/90 mm Hg. Hypertension expresses itself in various symptoms such as fatigue, irregular pulse rate, headache, dizziness, chest pain etc.

Angina Pectoris: Discomfort in the chest or the heart is referred to as angina. It occurs when the workload on the heart increases and when the heart does not get as much blood as it needs. Symptoms of angina include chest tightness, pressure and heaviness in the chest.