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Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Amlosafe MT 50 Tablet

Amlosafe MT 50 Tablet belongs to the group of antihypertensive agents used to treat high blood pressure/hypertension and angina pectoris. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Angina is basically a pain in the heart and chest. 

Amlosafe MT 50 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Amlosafe MT 50 Tablet helps treat high blood pressure.

Take Amlosafe MT 50 Tablet as prescribed. In some cases, Amlosafe MT 50 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Keep your doctor informed in case you are due to undergo any surgery or dental procedure. Avoid consuming alcohol with Amlosafe MT 50 Tablet as there may be an interaction. Amlosafe MT 50 Tablet  may cause dizziness, therefore, drive only if you are alert.

Uses of Amlosafe MT 50 Tablet

Hypertension, Angina pectoris

Directions for Use

Take Amlosafe MT 50 Tablet with or without food as directed by the physician. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Amlosafe MT 50 Tablet is a combination antihypertensive medication containing Metoprolol succinate and Amlodipine. It is used primarily to treat hypertension and to relax the blood vessels for seamless flow of blood. Metoprolol succinate is a beta-blocker that eases the symptoms of hypertension by blocking catecholamines that lead to increased pressure and heart rate. Amlodipine is a calcium channel blocker that decreases blood pressure by preventing the influx of calcium ions into cells and by enlarging and relaxing arteries. In addition, Amlosafe MT 50 Tablet also reduces the oxygen demands of the heart, relaxing the heart and blood vessels and requiring the heart to do less work.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amlosafe MT 50 Tablet

  • Tiredness
  • Dizziness
  • Headache
  • Ankle swelling
  • Slow heart rate
  • Stomach pain
  • Shortness of breath
  • Rash or itch
  • Cold hands and feet

Drug Warnings

Amlosafe MT 50 Tablet should not be used in case of any known allergy to either of the components. Amlosafe MT 50 Tablet should be used with caution in case of high risk or previous history of any arterial or thrombotic disorders, shock, cardiovascular health disorders, diabetes, heart failure, or any disease-causing psoriasis. Please inform your doctor in case of any history of an overactive thyroid, asthma, phaeochromocytoma (high BP due to a tumour in the adrenal glands), myasthenia gravis (neuromuscular disorder), COPD, heart block, liver disease or renal disease. Consult your doctor before using Amlosafe MT 50 Tablet during pregnancy or breastfeeding. Keep your doctor informed in case you are waiting to undergo any surgery or dental procedure. Amlosafe MT 50 Tablet may interact with alcohol, please consult your doctor before use. Amlosafe MT 50 Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert. 

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipinePhenytoin
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amlosafe MT 50 Tablet:
Using Amlosafe MT 50 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amlosafe MT 50 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipinePhenytoin
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Using Amlosafe MT 50 Tablet and phenytoin together may drastically lower Amlosafe MT 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Amlosafe MT 50 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineLemborexant
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of lemborexant and Amlosafe MT 50 Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Amlosafe MT 50 Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Using Amlosafe MT 50 Tablet and mitotane together may drastically lower Amlosafe MT 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlosafe MT 50 Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Amlosafe MT 50 Tablet and Idelalisib may raise Amlosafe MT 50 Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Amlosafe MT 50 Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineEnzalutamide
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Using a combination of Amlosafe MT 50 Tablet and enzalutamide may drastically lower Amlosafe MT 50 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Amlosafe MT 50 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineTizanidine
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Co-administration of Tizanidine and Amlosafe MT 50 Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Amlosafe MT 50 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Amlosafe MT 50 Tablet and Rifapentine may significantly reduce the blood levels of Amlosafe MT 50 Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Amlosafe MT 50 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineDolasetron
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Using dolasetron together with Amlosafe MT 50 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Amlosafe MT 50 Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineRifampicin
Severe
How does the drug interact with Amlosafe MT 50 Tablet:
Coadministration of Amlosafe MT 50 Tablet and rifampicin together may lower Amlosafe MT 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlosafe MT 50 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Limit the intake of salt in your diet.
  • Cut back on foods that are high in fat and cholesterol.
  • Eat more fruits, vegetables and whole-grain foods.
  • Avoid taking Amlosafe MT 50 Tablet with grapefruit juice as there may be an interaction.
  • Avoid tobacco use. Inform your doctor in case of marijuana use.
  • Dress warmly, as Amlosafe MT 50 Tablet may cause cold extremities.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Amlosafe MT 50 Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Amlosafe MT 50 Tablet works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.

Do not stop taking Amlosafe MT 50 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Amlosafe MT 50 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Amlosafe MT 50 Tablet .

Hyponatremia (a term for low blood sodium levels) often results in lowering blood pressure and falls. One of the not so common side-effects of Amlosafe MT 50 Tablet is dizziness and lowered BP. Hence, it is best to consult your physician before taking Amlosafe MT 50 Tablet if you suffer from this condition.

Light-headedness could be a side-effect of Amlosafe MT 50 Tablet . It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Amlosafe MT 50 Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Amlosafe MT 50 Tablet is not known to affect fertility. However, not enough literature and studies exist to ascertain the effect of Amlosafe MT 50 Tablet on fertility. Please consult your doctor in case of any concerns.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROPAFENONE
  • FLUOXETINE
  • PAROXETINE
  • DILTIAZEM
  • CLONIDINE
  • VERAPAMIL
  • ERYTHROMYCIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • RITONAVIR
  • DIGITALIS

Special Advise

  • In case you miss a dose of Amlosafe MT 50 Tablet , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule. Do not ever take a double dose.
  • If you accidentally take an extra dose of Amlosafe MT 50 Tablet , please inform your doctor immediately. Some of the common symptoms of an overdose can be low blood pressure, slow pulse rate, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin.
  • Do not discontinue taking Amlosafe MT 50 Tablet abruptly or without the advice of the physician.
  • Please know that your doctor may order blood tests to check your tolerance and need of Amlosafe MT 50 Tablet .
  • Amlosafe MT 50 Tablet should be used with caution in case of those over 80 or under 40 years of age.

Disease/Condition Glossary

Hypertension: Hypertension is defined as a condition in which the blood pressure remains high persistently. Normal BP is marked at 120/80 mmHg. Hypertension is defined as consistent blood pressure over 140/90 mm Hg. Hypertension expresses itself in various symptoms such as fatigue, irregular pulse rate, headache, dizziness, chest pain etc.

Angina Pectoris: Discomfort in the chest or the heart is referred to as angina. It occurs when the workload on the heart increases and when the heart does not get as much blood as it needs. Symptoms of angina include chest tightness, pressure and heaviness in the chest.

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