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Manufacturer/Marketer :

Unison Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

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Not Returnable

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About Mprol AM 5mg/50mg Tablet

Mprol AM 5mg/50mg Tablet belongs to the group of antihypertensive agents used to treat high blood pressure/hypertension and angina pectoris. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Angina is basically a pain in the heart and chest. 

Mprol AM 5mg/50mg Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Mprol AM 5mg/50mg Tablet helps treat high blood pressure.

Take Mprol AM 5mg/50mg Tablet as prescribed. In some cases, Mprol AM 5mg/50mg Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Keep your doctor informed in case you are due to undergo any surgery or dental procedure. Avoid consuming alcohol with Mprol AM 5mg/50mg Tablet as there may be an interaction. Mprol AM 5mg/50mg Tablet  may cause dizziness, therefore, drive only if you are alert.

Uses of Mprol AM 5mg/50mg Tablet

Hypertension, Angina pectoris

Directions for Use

Take Mprol AM 5mg/50mg Tablet with or without food as directed by the physician. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Mprol AM 5mg/50mg Tablet is a combination antihypertensive medication containing Metoprolol succinate and Amlodipine. It is used primarily to treat hypertension and to relax the blood vessels for seamless flow of blood. Metoprolol succinate is a beta-blocker that eases the symptoms of hypertension by blocking catecholamines that lead to increased pressure and heart rate. Amlodipine is a calcium channel blocker that decreases blood pressure by preventing the influx of calcium ions into cells and by enlarging and relaxing arteries. In addition, Mprol AM 5mg/50mg Tablet also reduces the oxygen demands of the heart, relaxing the heart and blood vessels and requiring the heart to do less work.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mprol AM 5mg/50mg Tablet

  • Tiredness
  • Dizziness
  • Headache
  • Ankle swelling
  • Slow heart rate
  • Stomach pain
  • Shortness of breath
  • Rash or itch
  • Cold hands and feet

Drug Warnings

Mprol AM 5mg/50mg Tablet should not be used in case of any known allergy to either of the components. Mprol AM 5mg/50mg Tablet should be used with caution in case of high risk or previous history of any arterial or thrombotic disorders, shock, cardiovascular health disorders, diabetes, heart failure, or any disease-causing psoriasis. Please inform your doctor in case of any history of an overactive thyroid, asthma, phaeochromocytoma (high BP due to a tumour in the adrenal glands), myasthenia gravis (neuromuscular disorder), COPD, heart block, liver disease or renal disease. Consult your doctor before using Mprol AM 5mg/50mg Tablet during pregnancy or breastfeeding. Keep your doctor informed in case you are waiting to undergo any surgery or dental procedure. Mprol AM 5mg/50mg Tablet may interact with alcohol, please consult your doctor before use. Mprol AM 5mg/50mg Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert. 

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineItraconazole
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Using Mprol AM 5mg/50mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Mprol AM 5mg/50mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Coadministration of Mprol AM 5mg/50mg Tablet with itraconazole may significantly raise the blood levels and effects of Mprol AM 5mg/50mg Tablet.

How to manage the interaction:
Mprol AM 5mg/50mg Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineCarbamazepine
Severe
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Coadministration of Mprol AM 5mg/50mg Tablet and carbamazepine together may significantly reduce Mprol AM 5mg/50mg Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Mprol AM 5mg/50mg Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Coadministration of Mprol AM 5mg/50mg Tablet and Idelalisib may raise Mprol AM 5mg/50mg Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Mprol AM 5mg/50mg Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipinePhenobarbital
Severe
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Using phenobarbital and Mprol AM 5mg/50mg Tablet may drastically lower Mprol AM 5mg/50mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Mprol AM 5mg/50mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineDolasetron
Severe
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Using dolasetron together with Mprol AM 5mg/50mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Mprol AM 5mg/50mg Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineTizanidine
Severe
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Co-administration of Tizanidine and Mprol AM 5mg/50mg Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Mprol AM 5mg/50mg Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Coadministration of Mprol AM 5mg/50mg Tablet and Rifapentine may significantly reduce the blood levels of Mprol AM 5mg/50mg Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Mprol AM 5mg/50mg Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Using Mprol AM 5mg/50mg Tablet and primidone together may lower Mprol AM 5mg/50mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Mprol AM 5mg/50mg Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Mprol AM 5mg/50mg Tablet:
Coadministration of Mprol AM 5mg/50mg Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Mprol AM 5mg/50mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Limit the intake of salt in your diet.
  • Cut back on foods that are high in fat and cholesterol.
  • Eat more fruits, vegetables and whole-grain foods.
  • Avoid taking Mprol AM 5mg/50mg Tablet with grapefruit juice as there may be an interaction.
  • Avoid tobacco use. Inform your doctor in case of marijuana use.
  • Dress warmly, as Mprol AM 5mg/50mg Tablet may cause cold extremities.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Mprol AM 5mg/50mg Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Mprol AM 5mg/50mg Tablet works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.

Do not stop taking Mprol AM 5mg/50mg Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Mprol AM 5mg/50mg Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Mprol AM 5mg/50mg Tablet .

Hyponatremia (a term for low blood sodium levels) often results in lowering blood pressure and falls. One of the not so common side-effects of Mprol AM 5mg/50mg Tablet is dizziness and lowered BP. Hence, it is best to consult your physician before taking Mprol AM 5mg/50mg Tablet if you suffer from this condition.

Light-headedness could be a side-effect of Mprol AM 5mg/50mg Tablet . It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Mprol AM 5mg/50mg Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Mprol AM 5mg/50mg Tablet is not known to affect fertility. However, not enough literature and studies exist to ascertain the effect of Mprol AM 5mg/50mg Tablet on fertility. Please consult your doctor in case of any concerns.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROPAFENONE
  • FLUOXETINE
  • PAROXETINE
  • DILTIAZEM
  • CLONIDINE
  • VERAPAMIL
  • ERYTHROMYCIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • RITONAVIR
  • DIGITALIS

Special Advise

  • In case you miss a dose of Mprol AM 5mg/50mg Tablet , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule. Do not ever take a double dose.
  • If you accidentally take an extra dose of Mprol AM 5mg/50mg Tablet , please inform your doctor immediately. Some of the common symptoms of an overdose can be low blood pressure, slow pulse rate, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin.
  • Do not discontinue taking Mprol AM 5mg/50mg Tablet abruptly or without the advice of the physician.
  • Please know that your doctor may order blood tests to check your tolerance and need of Mprol AM 5mg/50mg Tablet .
  • Mprol AM 5mg/50mg Tablet should be used with caution in case of those over 80 or under 40 years of age.

Disease/Condition Glossary

Hypertension: Hypertension is defined as a condition in which the blood pressure remains high persistently. Normal BP is marked at 120/80 mmHg. Hypertension is defined as consistent blood pressure over 140/90 mm Hg. Hypertension expresses itself in various symptoms such as fatigue, irregular pulse rate, headache, dizziness, chest pain etc.

Angina Pectoris: Discomfort in the chest or the heart is referred to as angina. It occurs when the workload on the heart increases and when the heart does not get as much blood as it needs. Symptoms of angina include chest tightness, pressure and heaviness in the chest.

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