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Reviewed By Sunny S , MBBS
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Composition :

RANOLAZINE-500MG

Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Angidil SR 500 mg Tablet

Angidil SR 500 mg Tablet belongs to the class of anti-anginal medications. It is used alone or with other medicines to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines.

The active substance in Angidil SR 500 mg Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Angidil SR 500 mg Tablet is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Your doctor will tell you how to take the Angidil SR 500 mg Tablet based on your medical condition. You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of Angidil SR 500 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not consume Angidil SR 500 mg Tablet if you are allergic to any component in this medicine. Angidil SR 500 mg Tablet should not be stopped even if you feel better for the best results as it prevents any future harm. If you stop taking the Angidil SR 500 mg Tablet on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. Some lifestyle modifications are important for best results when taking Angidil SR 500 mg Tablet like smoking cessation, decreasing alcohol intake, eating well, regular exercise, and managing stress. Angidil SR 500 mg Tablet should be taken with caution if you have any liver or kidney problems. Also, inform your doctor if you are taking other medications to avoid unwanted side effects or contraindications.

Uses of Angidil SR 500 mg Tablet

Angina Pectoris

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Angidil SR 500 mg Tablet is prescribed for treating angina. Angidil SR 500 mg Tablet is an anti-anginal medication used to treat angina pectoris. It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Angidil SR 500 mg Tablet is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Angidil SR 500 mg Tablet

  • Constipation
  • Dizziness
  • Headache
  • Feeling sick

Drug Warnings

Angidil SR 500 mg Tablet should be taken with caution in liver/kidney disease, are pregnant, plan to become pregnant, or are breastfeeding, history of heart disease. Also, grapefruit juice should be avoided while taking Angidil SR 500 mg Tablet . As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery. Do regular exercise to avoid the feeling of heaviness in the abdomen.

Drug-Drug Interactions

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RanolazineArmodafinil
Critical
RanolazinePosaconazole
Critical

Drug-Drug Interactions

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RanolazineArmodafinil
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
When Armodafinil is taken with Angidil SR 500 mg Tablet, the metabolism of Angidil SR 500 mg Tablet can be increased when combined with Armodafinil.

How to manage the interaction:
Taking Angidil SR 500 mg Tablet with Armodafinil is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
RanolazinePosaconazole
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
When Posaconazole is taken with Angidil SR 500 mg Tablet, may significantly increase the blood levels and effects of Angidil SR 500 mg Tablet.

How to manage the interaction:
Although there is an interaction between posaconazole and Angidil SR 500 mg Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
RanolazineMifepristone
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
When Mifepristone is taken with Angidil SR 500 mg Tablet, may cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Phenylbutazone with Angidil SR 500 mg Tablet can lead to an interaction. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop taking any medications without consulting a doctor.
RanolazinePentobarbital
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
When Angidil SR 500 mg Tablet is taken with Pentobarbital, may significantly reduce the blood levels of Angidil SR 500 mg Tablet, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Phenobarbital with Angidil SR 500 mg Tablet can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazineRifabutin
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
Taking Rifabutin and Angidil SR 500 mg Tablet may significantly reduce the blood levels of Angidil SR 500 mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Rifabutin and Angidil SR 500 mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RanolazineDelavirdine
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
Co-administration of Delavirdine and Angidil SR 500 mg Tablet may significantly increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Delavirdine with Angidil SR 500 mg Tablet can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop taking any medications without consulting a doctor.
RanolazineRibociclib
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
When Ribociclib is taken with Angidil SR 500 mg Tablet, may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Angidil SR 500 mg Tablet with Rifampicin is not recommended, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as excessive drowsiness, dizziness, lightheadedness, fainting, confusion, shortness of breath, or heart palpitations. Do not stop taking any medications without consulting a doctor.
RanolazineOxcarbazepine
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
When Angidil SR 500 mg Tablet is taken with Oxcarbazepine, may significantly reduce the blood levels of Angidil SR 500 mg Tablet, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Oxcarbazepine with Angidil SR 500 mg Tablet is not recommended as it can lead to an interaction, they can be taken together if advised by a doctor. Do not stop taking any medications without consulting a doctor.
RanolazineItraconazole
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
The blood levels and effects of Angidil SR 500 mg Tablet may be greatly increased when it is used with Itraconazole.

How to manage the interaction:
Although Angidil SR 500 mg Tablet and Itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop any negative symptoms, including fainting, lightheadedness, dizziness, or rapid heartbeat. Without consulting a doctor, never stop taking any medication.
RanolazineBexarotene
Critical
How does the drug interact with Angidil SR 500 mg Tablet:
When Angidil SR 500 mg Tablet and Bexarotene are taken together, may reduce the blood levels and effects of Angidil SR 500 mg Tablet.

How to manage the interaction:
Taking Angidil SR 500 mg Tablet with Bexarotene together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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RANOLAZINE-500MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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RANOLAZINE-500MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grapefruit juice can increase the levels of Angidil SR 500 mg Tablet, and high blood levels of food can occasionally cause an irregular heart rhythm that may be serious. Grapefruit and grapefruit juice should be avoided while taking Angidil SR 500 mg Tablet if possible.

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.
  • If you suffer from kidney or liver disease, please inform your doctor before taking the Angidil SR 500 mg Tablet .
  • Alcohol consumption along with Angidil SR 500 mg Tablet should be avoided as it may cause excessive drowsiness and increase muscle pain.
  • As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Angidil SR 500 mg Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

The active substance in Angidil SR 500 mg Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Angidil SR 500 mg Tablet is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

No, Angidil SR 500 mg Tablet does not stop acute attacks (sudden attacks) of angina, but Angidil SR 500 mg Tablet helps prevent a new attack.

No, alcohol should not be taken with Angidil SR 500 mg Tablet as it may lead to unwanted side effects and increase angina attacks.

Yes, smoking (tobacco) decreases the efficacy of Angidil SR 500 mg Tablet , especially when taken for angina (chest pain), so it should be avoided while taking Angidil SR 500 mg Tablet .

Yes, Angidil SR 500 mg Tablet can cause an upset stomach when taken empty stomach. So, to avoid it, Angidil SR 500 mg Tablet should be taken with a meal for best results.

Yes, Angidil SR 500 mg Tablet can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • QUINIDINE
  • DOFETILIDE
  • SOTALOL
  • KETOCONAZOLE
  • ITRACONAZOLE

Disease/Condition Glossary

Angina pectoris: Angina pectoris is discomfort in the chest or chest pain that generally occurs due to coronary artery disease (CAD) when you adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, but it does not stop an acute attack of angina pectoris.

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