Apixagress 5 Tablet 10's

Apixagress 5 Tablet 10's belongs to a class of drugs called 'anticoagulants' (blood thinners) primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung). Additionally, Apixagress 5 Tablet 10's is used to prevent blood clots in patients with atrial fibrillation (irregular heartbeat). Deep vein thrombosis is a condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. Atrial fibrillation is a condition that causes irregular, often fast heartbeat.

Apixagress 5 Tablet 10's contains Apixaban that works by inhibiting the action of blood clotting factor (X a) which is an important element of blood clotting. Thereby, it prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein) and helps in preventing blood clot formation.

Take Apixagress 5 Tablet 10's as prescribed. Your doctor will advise you how often you take Apixagress 5 Tablet 10's based on your medical condition. Some people may experience nausea, anemia (lack of blood), and unusual bleeding, including swelling and bruising. Most of these side effects of Apixagress 5 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Apixagress 5 Tablet 10's or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Apixagress 5 Tablet 10's. If you have a stomach ulcer, recent bleeding in the brain, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Apixagress 5 Tablet 10's. Your doctor may suggest a blood test called 'international normalized ratio' (INR) to check how quickly your blood's clotting. This test result will help your doctor to decide exactly when you should start taking Apixagress 5 Tablet 10's.

Apixagress 5 Tablet 10's is primarily used to prevent and treat blood clots in the body by inhibiting the action of clotting factor Xa which is important element of blood clotting. Thereby, prevents conversion of fibrinogen to fibrin (a protein that binds platelets together and forms a clot) and helps in preventing blood clots formation.

• Nausea
• Anaemia (lack of blood)
• Bleeding including swelling and bruising

Apixagress 5 Tablet 10's should not be used in children. Blood tests are advised before and while taking Apixagress 5 Tablet 10's to monitor kidney and liver functioning. If you are pregnant or breastfeeding, please inform your doctor before taking Apixagress 5 Tablet 10's. If you have a stomach ulcer, recent bleeding in the brain, kidney or liver problems, high blood pressure or bleeding problems, antiphospholipid syndrome (an immune system disorder that causes an increased risk of blood clots), inform your doctor before taking Apixagress 5 Tablet 10's.

Drug-Drug Interaction: Apixagress 5 Tablet 10's may have interaction with pain killers (acetylsalicylic acid, naproxen, ibuprofen), heart-related medicines (diltiazem), antidepressants (nortriptyline, amitriptyline), antifungal drugs (ketoconazole), antibiotics (rifampicin), epilepsy or fits related medicines (phenytoin), anti-HIV/AIDS drugs (ritonavir) and blood thinners (warfarin, enoxaparin, heparin, clopidogrel, rivaroxaban, dabigatran).

Drug-Food Interaction: Apixagress 5 Tablet 10's may interact with St John’s Wort (herbal supplement for depression). Limit intake of alcohol and do not exceed 14 units per week as it may increase the risk of bleeding.

Drug-Disease Interaction: If you have a stomach ulcer, recent bleeding in the brain, kidney or liver problems, high blood pressure or bleeding problems, antiphospholipid syndrome (an immune disorder of bleeding),  inform your doctor before taking Apixagress 5 Tablet 10's.

• ASPIRIN
• CLOPIDOGREL
• DILTIAZEM
• HEPARIN
• IBUPROFEN
• NAPROXEN
• RIVAROXABAN

• Avoid vitamin K rich foods such as coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, Brussels sprouts as they may decrease the effectiveness of Apixagress 5 Tablet 10's.
• Do regular exercise as it helps to dissolve blood clots especially in obese people.
• Do not consume more than 14 units of alcohol per week as excess alcohol intake may increase the risk of bleeding and quit smoking.

Complete blood count (CBC), INR test, prothrombin tests are advised before and while taking Apixagress 5 Tablet 10's.

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in lung) is a condition which occurs as the blood clots break and travel to lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain and shortness of breath. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

Atrial fibrillation is a condition that causes irregular, often fast heartbeat. In atrial fibrillation condition, blood clots are formed as blood is pooled in the upper chambers of heart.