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  3. Azatend-O 200 mg Tablet 14's

Azatend-O 200 mg Tablet 14's, Pack of 1 TABLET
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

AZACITIDINE-200MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Azatend-O 200 mg Tablet

Azatend-O 200 mg Tablet belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of acute myeloid leukaemia in adults who improved after chemotherapy but could not complete intensive curative therapy. Acute myeloid leukaemia is a type of cancer that forms in the blood-forming cells of the bone marrow.

Azatend-O 200 mg Tablet contains Azacitidine, which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.
 
In some cases, Azatend-O 200 mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, constipation, fatigue and abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Azatend-O 200 mg Tablet if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Azatend-O 200 mg Tablet . This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Azatend-O 200 mg Tablet

Acute myeloid leukaemia

Directions for Use

Take Azatend-O 200 mg Tablet with or without food. Swallow the medicine as a whole with water; do not crush or chew it.

Medicinal Benefits

Azatend-O 200 mg Tablet belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of adult patients with acute myeloid leukaemia who achieved first complete remission (all signs and symptoms of cancer have disappeared) or complete remission with incomplete blood count recovery following intensive induction chemotherapy and are not able to complete intensive curative therapy. Azatend-O 200 mg Tablet contains Azacitidine, a nucleoside metabolic inhibitor which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.

Storage

Store in a cool and dry place away from sunlight
Side effects of Azatend-O 200 mg Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink clear fluids like water and eat a high-fiber diet.
  • Practice to get enough rest.
  • Take mild pain relievers.
  • Apply a hot water bottle or heated wheat pack to your abdomen.
  • Avoid taking foods that are fatty, spicy, or rich.
  • Do not take alcohol, tea, and coffee.
  • Practice technics like biofeedback, hypnosis, or other methods for stress relief.
  • Consult your doctor, if you experience severe abdominal pain or pain that comes back.
  • Eat a well-balanced diet, and avoid highly processed foods.
  • Regular exercise can help prevent ascites.
  • Maintain a healthy weight, as obesity is a risk factor for ascites.
  • Limit salt intake; try to consume no more than 2,000–4,000 milligrams of salt per day.
  • Avoid alcohol, as it can damage your liver and increase the risk of cirrhosis.
  • Practice safe sex, unprotected sex can lead to hepatitis, which can damage the liver and cause cirrhosis.
  • Get vaccinated for diseases like hepatitis, influenza, and pneumococcal.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Drug Warnings

Do not take Azatend-O 200 mg Tablet if you are allergic to any of its components or if you are breastfeeding. Inform the doctor if you have liver or kidney problems. Seek medical attention if you experience symptoms of neutropenia/low white blood cells (fever or chills, feeling very tired or weak, body aches, and unusual headache) or thrombocytopenia/low platelet count (unusual bleeding or bruising). Consult the doctor if you are pregnant, plan to become pregnant, or if you plan to father a child.

Drug-Drug Interactions

verifiedApollotooltip
AzacitidineYellow fever vaccine
Critical
AzacitidineFingolimod
Severe

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
How does the drug interact with Azatend-O 200 mg Tablet:
Taking Yellow fever vaccine with Azatend-O 200 mg Tablet can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Azatend-O 200 mg Tablet and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
AzacitidineFingolimod
Severe
How does the drug interact with Azatend-O 200 mg Tablet:
The use of fingolimod in conjunction with Azatend-O 200 mg Tablet may raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azatend-O 200 mg Tablet with Fingolimod can possibly result in an interaction, but it can be taken if your doctor has advised it. However, Consult a doctor immediately if you have a fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineInfliximab
Severe
How does the drug interact with Azatend-O 200 mg Tablet:
Taking Infliximab with Azatend-O 200 mg Tablet can increase the risk or severity of developing infection.

How to manage the interaction:
Although taking Azatend-O 200 mg Tablet and Infliximab together can cause an interaction, it can be taken if a doctor has suggested it. If you experience symptoms like fever, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, and pain or burning during urination, it is recommended to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineDeferiprone
Severe
How does the drug interact with Azatend-O 200 mg Tablet:
Taking Azatend-O 200 mg Tablet with Deferiprone can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Azatend-O 200 mg Tablet with Deferiprone can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
AzacitidineClozapine
Severe
How does the drug interact with Azatend-O 200 mg Tablet:
Using clozapine together with Azatend-O 200 mg Tablet can lower white blood cell count and may affect the bone marrow function, that may develop serious infections as a result.

How to manage the interaction:
There may be a possibility of interaction between Azatend-O 200 mg Tablet and Clozapine, but it can be taken if prescribed by a doctor. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without a doctor's advice.
AzacitidineTofacitinib
Severe
How does the drug interact with Azatend-O 200 mg Tablet:
Taking Azatend-O 200 mg Tablet with tofacitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Azatend-O 200 mg Tablet and Tofacitinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineLeflunomide
Severe
How does the drug interact with Azatend-O 200 mg Tablet:
Taking Azatend-O 200 mg Tablet and leflunomide together may increase the chances of developing severe infections.

How to manage the interaction:
Although there is an interaction between leflunomide and Azatend-O 200 mg Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineTeriflunomide
Severe
How does the drug interact with Azatend-O 200 mg Tablet:
Taking Azatend-O 200 mg Tablet with Teriflunomide can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Azatend-O 200 mg Tablet and Teriflunomide together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
AzacitidineFilgrastim
Severe
How does the drug interact with Azatend-O 200 mg Tablet:
Coadministration of Filgrastim with Azatend-O 200 mg Tablet can reduce the effects of Filgrastim.

How to manage the interaction:
Although there is an interaction between filgrastim and Azatend-O 200 mg Tablet, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AzacitidineCertolizumab
Severe
How does the drug interact with Azatend-O 200 mg Tablet:
Taking Azatend-O 200 mg Tablet with Certolizumab may raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azatend-O 200 mg Tablet with Certolizumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly as it helps maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Azatend-O 200 mg Tablet Substitute

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Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:50 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Azatend-O 200 mg Tablet works by helping bone marrow in the production of normal blood cells and killing abnormal cells in the bone marrow.

Azatend-O 200 mg Tablet may affect fertility in men and women. Consult the doctor if you have any concerns.

The doctor will prescribe anti-nausea medicine to help prevent nausea and vomiting during treatment with Azatend-O 200 mg Tablet . Take the anti-nausea medicine 30 minutes before each dose of Azatend-O 200 mg Tablet or as the doctor advises.

If you vomit after taking a dose Azatend-O 200 mg Tablet , avoid taking another dose on the same day. Take the next dose at the regular time the next day. Talk to the doctor if you have any concerns.

Special Advise

  • If you are a female, you should take a pregnancy test prior to the start of the treatment. Use reliable contraception to prevent pregnancy during treatment and for 6 months after the last dose.
  • Male patients with partners of reproductive potential should use effective contraception during treatment and for 3 months after stopping the treatment.
  • If the powder from the medicine comes in contact with your skin, wash the area well with soap and water immediately.
  • If the powder from the medicine comes in contact with mucous membranes (eyes or mouth), flush the area with water immediately.

Disease/Condition Glossary

Acute myeloid leukaemia: Acute myeloid leukaemia, also called acute myelogenous leukaemia or acute nonlymphocytic leukaemia, is the cancer of blood and bone marrow with excess immature white blood cells. Symptoms include fever, recurrent infections, fatigue, and easy bruising.

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