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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bactrim DS Tablet

Bactrim DS Tablet belongs to the group of medicines called ‘antibiotics’ used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Bactrim DS Tablet does not work against infections caused by the virus, including cold and flu. 

Bactrim DS Tablet is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Bactrim DS Tablet stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Your doctor will decide the dose and duration of Bactrim DS Tablet based on your condition and the severity of the infection. In some cases, you may experience certain common side-effects such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side-effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Before starting Bactrim DS Tablet , please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Bactrim DS Tablet on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Bactrim DS Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Bactrim DS Tablet is not recommended for children below 12years.

Uses of Bactrim DS Tablet

Bacterial infections

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use.

Medicinal Benefits

Bactrim DS Tablet belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bactrim DS Tablet is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Bactrim DS Tablet kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Bactrim DS Tablet is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

Storage

Keep Bactrim DS Tablet out of reach and sight of children.

Drug Warnings

Do not take Bactrim DS Tablet if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Bactrim DS Tablet if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Bactrim DS Tablet to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Bactrim DS Tablet:
Taking Bactrim DS Tablet with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Bactrim DS Tablet and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bactrim DS Tablet:
Co-administration of Calcium folinate with Bactrim DS Tablet may increase rates of treatment failure.

How to manage the interaction:
Although there is an interaction between calcium folinate and Bactrim DS Tablet, but it can be taken together if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Bactrim DS Tablet:
Coadministration of Azilsartan medoxomil with Bactrim DS Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between azilsartan medoxomil and Bactrim DS Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, or tingling in your hands and feet. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Bactrim DS Tablet:
Taking perindopril with Bactrim DS Tablet can cause hyperkalemia(high levels of potassium in blood) which can increase the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Co-administration of Perindopril with Bactrim DS Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.
TrimethoprimIvacaftor
Severe
How does the drug interact with Bactrim DS Tablet:
When Bactrim DS Tablet is taken with Ivacaftor, the amount of Bactrim DS Tablet in the blood increases.

How to manage the interaction:
Taking Bactrim DS Tablet with Ivacaftor together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting your doctor.
TrimethoprimPotassium iodide
Severe
How does the drug interact with Bactrim DS Tablet:
Taking Potassium Iodide with Bactrim DS Tablet can make high levels of potassium in the blood which can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Potassium iodide and Bactrim DS Tablet, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
TrimethoprimQuinidine
Severe
How does the drug interact with Bactrim DS Tablet:
Using Bactrim DS Tablet can cause higher levels of Quinidine in the blood which increases risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Bactrim DS Tablet and Quinidine, but it can be taken if prescribed by a doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Bactrim DS Tablet:
Taking Ramipril with Bactrim DS Tablet can increase the potassium levels in the blood, increasing the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between ramipril and Bactrim DS Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Bactrim DS Tablet:
Co-administration of Bactrim DS Tablet with phenytoin may increase the blood levels and effects of phenytoin.

How to manage the interaction:
Although there is an interaction between Bactrim DS Tablet and phenytoin but can be taken together if prescribed by doctor. However, if you experience nausea, vomiting, twitching eye movements, blurred vision, difficult to speak, loss of balance or coordination, tremors (shaking of hands legs), and confusion contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.
How does the drug interact with Bactrim DS Tablet:
Coadministration of Losartan with Bactrim DS Tablet can increase potassium levels which can lead to severe conditions like kidney problems.

How to manage the interaction:
Taking Losartan with Bactrim DS Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Bactrim DS Tablet is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Bactrim DS Tablet kills the bacteria and stops their growth. Thereby, helps to treat bacterial infections.

Bactrim DS Tablet causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Diarrhoea might be a side-effect of Bactrim DS Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Bactrim DS Tablet and consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Bactrim DS Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to recurring infections. Continue taking Bactrim DS Tablet for as long as your doctor has prescribed to treat your condition effectually.

Do not take Bactrim DS Tablet on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

Bactrim DS Tablet may affect certain laboratory test results. Inform the person doing the tests that you are taking Bactrim DS Tablet .

Bactrim DS Tablet may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Bactrim DS Tablet .

Drug-Drug Interactions Checker List

  • GLIBENCLAMIDE
  • AZITHROMYCIN
  • METRONIDAZOLE
  • ALBUTEROL
  • BENDROFLUMETHIAZIDE
  • GLICLAZIDE

Special Advise

  • Bactrim DS Tablet may affect certain laboratory test results such as blood tests. Inform the person doing the tests that you are taking Bactrim DS Tablet . 
  • Your doctor may advise you to get regular tests if you have kidney problems or if you have been prescribed Bactrim DS Tablet for a longer duration, to know if the medicine is working properly.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

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