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Prescription drugWhats That
Synonym :
GLIMEPIRIDE+METFORMIN HYDROCHLORIDE
Composition :
GLIMEPIRIDE-1MG + METFORMIN-500MG
Manufacturer/Marketer :
Biocon Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Blisto 1 Mf Tab:
Taking Blisto 1 Mf Tab with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.
How to manage the interaction:
Gatifloxacin is not recommended for patients with diabetes, however, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Taking Blisto 1 Mf Tab with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.
How to manage the interaction:
Gatifloxacin is not recommended for patients with diabetes, however, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Severe
How does the drug interact with Blisto 1 Mf Tab:
Co-administration of Sparfloxacin with Blisto 1 Mf Tab can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Blisto 1 Mf Tab can be taken with Sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat (or) symptoms of high blood sugar like increased thirst, increased hunger, and increased urination. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Sparfloxacin with Blisto 1 Mf Tab can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Blisto 1 Mf Tab can be taken with Sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat (or) symptoms of high blood sugar like increased thirst, increased hunger, and increased urination. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepiridePromazine
Severe
How does the drug interact with Blisto 1 Mf Tab:
When Blisto 1 Mf Tab is taken with Promazine may interfere with blood glucose control and reduce the effectiveness of Blisto 1 Mf Tab.
How to manage the interaction:
There may be a possibility of interaction between Blisto 1 Mf Tab and Promazine, but it can be taken if prescribed by a doctor. It's important to keep an eye on how much urine you're producing. If you notice any of these signs - very high or very low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
When Blisto 1 Mf Tab is taken with Promazine may interfere with blood glucose control and reduce the effectiveness of Blisto 1 Mf Tab.
How to manage the interaction:
There may be a possibility of interaction between Blisto 1 Mf Tab and Promazine, but it can be taken if prescribed by a doctor. It's important to keep an eye on how much urine you're producing. If you notice any of these signs - very high or very low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
GlimepirideEnoxacin
Severe
How does the drug interact with Blisto 1 Mf Tab:
Taking Blisto 1 Mf Tab with Enoxacin, may affect blood glucose levels which may lead to hypoglycemia (low blood glucose) and hyperglycemia (high blood glucose).
How to manage the interaction:
Taking Blisto 1 Mf Tab with Enoxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. This can be a good thing if you need help lowering your blood sugar, but it can also be a problem if it goes too low. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
Taking Blisto 1 Mf Tab with Enoxacin, may affect blood glucose levels which may lead to hypoglycemia (low blood glucose) and hyperglycemia (high blood glucose).
How to manage the interaction:
Taking Blisto 1 Mf Tab with Enoxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. This can be a good thing if you need help lowering your blood sugar, but it can also be a problem if it goes too low. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Blisto 1 Mf Tab:
Concomitant use of bisoprolol with Blisto 1 Mf Tab may increase the risk, severity, and/or duration of hypoglycemia (low blood sugar). It may also mask some of the symptoms of hypoglycemia such as palpitation, tremor, and rapid heartbeat, making it more difficult to recognize an oncoming episode.
How to manage the interaction:
Although there may be an interaction, bisoprolol can be taken with Blisto 1 Mf Tab if prescribed by the doctor. Consult the prescriber if you develop symptoms of low blood sugar like shakiness, dizziness, sweating, nausea, hunger, weakness, or lightheadedness.
Concomitant use of bisoprolol with Blisto 1 Mf Tab may increase the risk, severity, and/or duration of hypoglycemia (low blood sugar). It may also mask some of the symptoms of hypoglycemia such as palpitation, tremor, and rapid heartbeat, making it more difficult to recognize an oncoming episode.
How to manage the interaction:
Although there may be an interaction, bisoprolol can be taken with Blisto 1 Mf Tab if prescribed by the doctor. Consult the prescriber if you develop symptoms of low blood sugar like shakiness, dizziness, sweating, nausea, hunger, weakness, or lightheadedness.
Severe
How does the drug interact with Blisto 1 Mf Tab:
Taking Blisto 1 Mf Tab with sunitinib may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Blisto 1 Mf Tab can be taken with sunitinib if prescribed by the doctor. Consult the prescriber if you experience symptoms if low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Blisto 1 Mf Tab with sunitinib may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Blisto 1 Mf Tab can be taken with sunitinib if prescribed by the doctor. Consult the prescriber if you experience symptoms if low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideAminolevulinic acid
Severe
How does the drug interact with Blisto 1 Mf Tab:
Aminolevulinic acid sensitizes your skin to bright lights and combining it with other medications that can also have this effect (i.e., photosensitivity) such as Blisto 1 Mf Tab may increase the risk of a severe sunburn.
How to manage the interaction:
Taking Blisto 1 Mf Tab with Aminolevulinic acid together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Aminolevulinic acid sensitizes your skin to bright lights and combining it with other medications that can also have this effect (i.e., photosensitivity) such as Blisto 1 Mf Tab may increase the risk of a severe sunburn.
How to manage the interaction:
Taking Blisto 1 Mf Tab with Aminolevulinic acid together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Blisto 1 Mf Tab:
Taking Clarithromycin with Blisto 1 Mf Tab may increase the effects of Blisto 1 Mf Tab on lowering blood sugar.
How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Blisto 1 Mf Tab if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, hunger, weakness, dizziness, drowsiness, nervousness, sweating, confusion, and tremor. Do not discontinue the medications without consulting a doctor.
Taking Clarithromycin with Blisto 1 Mf Tab may increase the effects of Blisto 1 Mf Tab on lowering blood sugar.
How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Blisto 1 Mf Tab if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, hunger, weakness, dizziness, drowsiness, nervousness, sweating, confusion, and tremor. Do not discontinue the medications without consulting a doctor.
Severe
How does the drug interact with Blisto 1 Mf Tab:
Taking Blisto 1 Mf Tab with Sibutramine may lose the weight and may leads to hypoglycemia sometimes.
How to manage the interaction:
Although there is a possible interaction, Blisto 1 Mf Tab can be taken with sibutramine if prescribed by the doctor. The doctor may advise frequent monitoring of a blood sugar and adjustment of your diabetic regimen both during and after treatment with sibutramine. Let the doctor know if you experience symptoms of low blood glucose such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Blisto 1 Mf Tab with Sibutramine may lose the weight and may leads to hypoglycemia sometimes.
How to manage the interaction:
Although there is a possible interaction, Blisto 1 Mf Tab can be taken with sibutramine if prescribed by the doctor. The doctor may advise frequent monitoring of a blood sugar and adjustment of your diabetic regimen both during and after treatment with sibutramine. Let the doctor know if you experience symptoms of low blood glucose such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Blisto 1 Mf Tab:
When Blisto 1 Mf Tab is taken with Nalidixic acid, can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
There may be a possibility of interaction between Blisto 1 Mf Tab and Nalidixic acid, but it can be taken if prescribed by a doctor. It's important to monitor your blood sugar levels closely. If you experience symptoms like kidney problems, low or high blood sugar, or other concerning symptoms, contact a doctor right away. They may be able to suggest alternative medications that won't interact with a diabetes treatment. Do not discontinue any medications without consulting a doctor.
When Blisto 1 Mf Tab is taken with Nalidixic acid, can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
There may be a possibility of interaction between Blisto 1 Mf Tab and Nalidixic acid, but it can be taken if prescribed by a doctor. It's important to monitor your blood sugar levels closely. If you experience symptoms like kidney problems, low or high blood sugar, or other concerning symptoms, contact a doctor right away. They may be able to suggest alternative medications that won't interact with a diabetes treatment. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
GLIMEPIRIDE-1MgHypertensive heart and renal disease
Severe
GLIMEPIRIDE-1MgUnspecified kidney failure
Severe
Drug-Diseases Interactions
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GLIMEPIRIDE-1MgHypertensive heart and renal disease
Severe
How does the disease interact with Blisto 1 Mf Tab:
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
GLIMEPIRIDE-1MgUnspecified kidney failure
Severe
How does the disease interact with Blisto 1 Mf Tab:
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
GLIMEPIRIDE-1MgOther disorders of adrenal gland
Moderate
How does the disease interact with Blisto 1 Mf Tab:
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
GLIMEPIRIDE-1MgAnaemia due to enzyme disorders
Moderate
How does the disease interact with Blisto 1 Mf Tab:
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
GLIMEPIRIDE-1MgOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Blisto 1 Mf Tab:
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
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