Sibutramine
About
Sibutramine belongs to the class of medication called anti-obesity drugs used to treat obesity and help lose weight. Sibutramine is recommended for obese patients with an initial body mass index (BMI) ≥ 30 kg/m2 or ≥ 27 kg/m2 in the presence of other risk factors (e.g., dyslipidemia or Abnormally elevated cholesterol or fats, diabetes, controlled hypertension). Sibutramine should be used along with a low-calorie diet and regular physical exercise. Obesity is a medical condition caused by excess body fat, making a person overweight and predisposing them to many conditions and disorders. Intake of more calories than you burn by exercise or daily activities results in obesity.
Sibutramine contains Sibutramine which causes weight loss by suppressing the appetite and promoting energy expenditure.
Take Sibutramine as prescribed by your doctor. You are advised to take Sibutramine for as long as your doctor has prescribed it for you based on your condition. Some people may experience dry mouth, headache, loss of appetite, trouble sleeping, and constipation. Most of these side effects of Sibutramine do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
Sibutramine is contraindicated in patients with hypersensitivity to Sibutramine or any of the inactive ingredients in it. Sibutramine is contraindicated in patients receiving monoamine oxidase inhibitors (MAOIs) or other centrally acting weight loss drugs. It is recommended not to use in patients with a major eating disorder (anorexia nervosa or bulimia nervosa). The use of Sibutramine during pregnancy and breastfeeding is not recommended. The efficacy of Sibutramine in adolescents who are obese has not been adequately studied. The concomitant use of Sibutramine and excess alcohol is not recommended.
Uses of Sibutramine
Medicinal Benefits
Sibutramine contains Sibutramine, an anti-obesity drug indicated for managing obesity, including weight loss and maintenance of weight loss, and should be used in conjunction with a reduced-calorie diet. Sibutramine is recommended for obese patients with an initial body mass index (BMI) ≥ 30 kg/m2 or ≥ 27 kg/m2 in the presence of other risk factors (e.g., dyslipidemia or Abnormally elevated cholesterol or fats, diabetes, controlled hypertension). Sibutramine causes weight loss by suppressing the appetite and by promoting energy expenditure. Sibutramine should be used along with a low-calorie diet and regular physical exercise. Thus, Sibutramine promotes weight loss and lowers the possibility of developing major health issues.
Directions for Use
Storage
Side Effects of Sibutramine
- Dry mouth
- Headache
- Loss of appetite
- Trouble sleeping
- Constipation
In-Depth Precautions and Warning
Drug Warnings
If you have an allergy to any ingredient in Sibutramine, it is advised that you avoid using it. While taking Sibutramine, women who are sexually active should use effective contraception. Patients should be instructed to inform their doctor immediately if they get pregnant or plan to get pregnant while taking Sibutramine. Sibutramine or its metabolites may be excreted in human milk; however, this is unknown. Therefore, using Sibutramine while breastfeeding is not advised. Since there is little knowledge on utilizing Sibutramine in teens, it is advised against doing so. Inform your doctor about your medical history and the other drugs you are currently taking before taking Sibutramine to rule out any possible side effects or interactions.
Drug Interactions
Drug-Drug Interactions: Sibutramine may interact with monoamine oxidase inhibitors or antidepressants (e.g. isocarboxazid, phenelzine, citalopram, clomipramine, doxepin), medicines used to prevent nausea and vomiting in certain conditions (e.g. ondansetron), medicines used to treat the symptoms of migraine headaches (e.g. sumatriptan) and other centrally acting weight loss drugs (e.g. merastin).
Drug-Food Interactions: Avoid high-fat meals and alcoholic beverages.
Drug-Disease Interactions: Sibutramine may interact with disease conditions, including anorexia nervosa (An eating disorder), cardiovascular disorders, glaucoma (eye conditions that can cause blindness) and renal/liver disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionDo not consume alcohol while on treatment with Sibutramine as it may cause serious side effects.
Pregnancy
cautionNo adequate and well-controlled studies with Sibutramine have been conducted on pregnant women. So, the use of Sibutramine during pregnancy is not recommended.
Breast Feeding
cautionIt is unknown whether sibutramine is excreted in human milk. Therefore, Sibutramine is not recommended for use in nursing mothers.
Driving
safe if prescribedIt is not known whether Sibutramine alters the ability to drive. Do not drive or operate machinery if you experience symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer.
Liver
cautionPatients with severe hepatic dysfunction have not been systematically studied; Sibutramine should not be used in such patients.
Kidney
cautionPatients with mild to severe renal impairment should use Sibutramine with caution. Patients with severe renal impairment, such as those receiving dialysis for end-stage renal disease, should not utilize Sibutramine.
Children
unsafeIt is unknown if sibutramine is safe and effective for use in pediatric patients under the age of 16.
Habit Forming
Diet & Lifestyle Advise
- Maintain a low-fat diet. Prefer skim milk and fat-free or low-fat dairy products.
- Avoid red meat and include lean meat such as salmon and chicken.
- Eat a healthy diet that includes fruits, vegetables, lean protein and whole grains.
- Avoid fried foods, fast food, instant food, pasta, burger, noodles and cookies.
- Limit your sugar intake, as excess sugar is stored as fat in the body.
- Do not skip meals to reduce weight but instead, take balanced meals.
- Do regular exercise such as swimming, cycling, walking or dancing for a minimum of 20 to 30 minutes daily.
- Avoid alcohol consumption.
Patients Concern
Disease/Condition Glossary
Obesity: Obesity is a common condition associated with excessive body fat, which in turn increases the risk of other health problems such as diabetes, high blood pressure, certain cancers and heart disease. Intake of more calories than you burn by exercise or daily activities results in obesity. Some common causes of obesity include insufficient sleep, growing older, pregnancy, genetics, hypothyroidism (underactive thyroid gland) or polycystic ovary syndrome (imbalance of female reproductive hormones). Proper diet and exercise are advised, along with medication to treat obesity.
FAQs
Sibutramine contains Sibutramine, an anti-obesity drug that causes weight loss by suppressing the appetite and promoting energy expenditure. Sibutramine should be used along with a low-calorie diet and regular physical exercise. Thus, Sibutramine promotes weight loss and lowers the possibility of developing major health issues.
Sibutramine substantially increases some patients' blood pressure and/or pulse rate. Regular pulse rate and blood pressure monitoring is required when prescribing Sibutramine.
If you take too much Sibutramine, call your doctor or Poison Control Center immediately, or go to the emergency room.
Sibutramine is contraindicated in patients with major eating disorders (anorexia nervosa or bulimia nervosa).
