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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

BOSENTAN-62.5MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bosentas 62.5 Tablet

Bosentas 62.5 Tablet is an anti-hypertension medication primarily used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). Bosentas 62.5 Tablet can even increase our exercising ability, delay disease progression, and improve quality of life. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart.

Bosentas 62.5 Tablet contains Bosentan, and an endothelin receptor antagonist used to treat pulmonary arterial hypertension. It works by blocking the action of endothelin.  Endothelin narrows the blood vessels and increases the pressure in the blood vessels of the lungs. Bosentas 62.5 Tablet helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs.

Take Bosentas 62.5 Tablet as prescribed by your doctor. You are advised to take Bosentas 62.5 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. You may experience swelling of legs and ankles, headaches, and diarrhoea in some cases. Most of these side effects of Bosentas 62.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Some rare cases may cause anaemia and abnormal liver function such as nausea, vomiting, dark urine, and fever, which your doctor should know.

Please inform your doctor if you have liver dysfunction before starting Bosentas 62.5 Tablet . If you are pregnant or breastfeeding, do not take Bosentas 62.5 Tablet a pregnancy category X drug. If you are taking Bosentas 62.5 Tablet , women should use a reliable form of the contraceptive pill to avoid pregnancy and continue to use it one month after stopping Bosentas 62.5 Tablet . Also, the blood test for liver functions should be monitored regularly and for haemoglobin level.

Uses of Bosentas 62.5 Tablet

Pulmonary arterial hypertension (PAH)

Directions for Use

Tablet: Bosentas 62.5 Tablet can be taken with or without food. It should be swallowed as a whole with a glass of water, do not chew or crush it.Tablets for oral suspension: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Medicinal Benefits

Bosentas 62.5 Tablet is an anti-hypertension medication primarily used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). Bosentas 62.5 Tablet can even increase our exercising ability, delay disease progression, and improve quality of life. It works by blocking the action of endothelin.  Endothelin narrows the blood vessels and increases the pressure in the blood vessels of the lungs. Bosentas 62.5 Tablet helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs. It also improves the quality of life, exercising ability, and delays the progression of pulmonary arterial hypertension.

Storage

Store in a cool and dry place away from sunlight
Side effects of Bosentas 62.5 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid diet rich in salt and carbohydrates
  • Drink plenty of water and stay hydrated.
  • Exercise regularly and maintain a healthy lifestyle.
  • Take potassium rich foods like potatoes, spinach, tomatoes, sea food and dairy products.
  • Take beverages containing caffeine like coffee and tea.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • To improve liver health and aid in the removal of toxins, drink lots of water.
  • Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
  • Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
  • You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.

Drug Warnings

Do not take Bosentas 62.5 Tablet if you are allergic to Bosentas 62.5 Tablet or any of its ingredients. Please inform your doctor if you have liver dysfunction before starting Bosentas 62.5 Tablet . If you are pregnant or breastfeeding, do not take Bosentas 62.5 Tablet as it is a pregnancy category X drug. It can lead to defects in the baby if taken during pregnancy. Also, after stoping Bosentas 62.5 Tablet at least after a gap of one month, you should try to conceive so that Bosentas 62.5 Tablet flushed out of body completely. If you are taking Bosentas 62.5 Tablet , women should use a reliable form of the contraceptive pill to avoid pregnancy and continue to use it one month after stopping Bosentas 62.5 Tablet . Blood tests for liver functions should be monitored regularly and for hemoglobin level as well. As low hemoglobin could be a sign of anemia.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Bosentas 62.5 Tablet:
Taking regorafenib with Bosentas 62.5 Tablet it can increases the risk of side effects.

How to manage the interaction:
Taking Regorafenib with Bosentas 62.5 Tablet is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Bosentas 62.5 Tablet:
When Bosentas 62.5 Tablet is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Ciclosporin with Bosentas 62.5 Tablet is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
BosentanOxycodone
Severe
How does the drug interact with Bosentas 62.5 Tablet:
Coadministration of oxycodone and Bosentas 62.5 Tablet may reduce the blood levels of oxycodone, which may make the medication less effective in treating your pain.

How to manage the interaction:
Although there is an interaction between Bosentas 62.5 Tablet and Oxycodone, you can take these medicines together if prescribed by your doctor. However, contact your doctor immediately if you experience watery eyes, runny nose, sneezing, yawning, excessive sweating, body aches, or abdominal cramping. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Bosentas 62.5 Tablet:
Bosentas 62.5 Tablet can lower the levels of Daclatasvir in your blood, which could decrease its effectiveness in treating your condition.

How to manage the interaction:
Although using Bosentas 62.5 Tablet and Daclatasvir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
BosentanBrigatinib
Severe
How does the drug interact with Bosentas 62.5 Tablet:
Coadministration of brigatinib and Bosentas 62.5 Tablet may reduce the blood levels of brigatinib, which may make the medication less effective in treating your condition.

How to manage the interaction:
Although taking Bosentas 62.5 Tablet and Brigatinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
BosentanCobicistat
Severe
How does the drug interact with Bosentas 62.5 Tablet:
Coadministration of Bosentas 62.5 Tablet with cobicistat may significantly increase the blood levels of Bosentas 62.5 Tablet, potentially increasing the risk of side effects.

How to manage the interaction:
Although taking Cobicistat and Bosentas 62.5 Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Bosentas 62.5 Tablet:
Co-administration of Dienogest with Bosentas 62.5 Tablet may decrease the effectiveness of Dienogest.

How to manage the interaction:
Although there is a possible interaction, Dienogest can be taken with Bosentas 62.5 Tablet if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Bosentas 62.5 Tablet:
Taking axitinib with Bosentas 62.5 Tablet may significantly reduce the blood levels of axitinib, making the medication less effective in treating the condition.

How to manage the interaction:
Although using Bosentas 62.5 Tablet and Axitinib together can result in an interaction, they can be taken together if advised by a doctor. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Bosentas 62.5 Tablet:
Taking Levonorgestrel and Bosentas 62.5 Tablet may lower the blood levels and effects of levonorgestrel, making it less effective.

How to manage the interaction:
Although taking levonorgestrel and Bosentas 62.5 Tablet can lead to interaction, it can be taken if prescribed by a doctor. However, if you experience hot flashes, vaginal dryness, or abdominal bleeding, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Bosentas 62.5 Tablet:
Taking Cariprazine with Bosentas 62.5 Tablet may reduce the blood levels of cariprazine, which may make the medication less effective.

How to manage the interaction:
Taking Bosentas 62.5 Tablet with Cariprazine together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with BMI 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Bosentas 62.5 Tablet is an anti-hypertension medication primarily used to treat pulmonary arterial hypertension. It works by blocking the action of endothelin. Endothelin narrows the blood vessels and increases the pressure in the blood vessels of the lungs. Bosentas 62.5 Tablet helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs.

Pulmonary arterial hypertension is high pressure in the blood vessels that carry blood from the heart to the lungs. It can be due to constriction of blood vessels or some blockage in blood vessels' pathway.

Yes, in rare cases, $Name can cause anaemia. It can decrease your haemoglobin level, which may lead to anaemia. So, please regularly check your haemoglobin level if you are taking Bosentas 62.5 Tablet .

Drug-Drug Interactions Checker List

  • AMIODARONE
  • ATORVASTATIN
  • SIMVASTATIN
  • ERYTHROMYCIN
  • RIFAMPICIN
  • FLUCONAZOLE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR
  • WARFARIN
  • CYCLOSPORINE
  • GLIBENCLAMIDE
  • SILDENAFIL
  • TADALAFIL

Special Advise

  • A blood test to check liver function should be regularly.
  • Blood test for low haemoglobin level should be checked regularly as it could be a sign of anaemia.
  • The pregnancy test is a must for women of childbearing potential.

Disease/Condition Glossary

 ,  ,Pulmonary arterial hypertension (PAH): High pressure in the blood vessels that carry blood from the heart to the lungs. It can be due to constriction of blood vessels or some blockage in blood vessels' pathway.

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