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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Bros Enterprises Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Brodase-D Tablet

Brodase-D Tablet belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of diclofenac and serratiopeptidase. Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage of the tooth nerve, infection, decay, extraction, or injury.

Brodase-D Tablet is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Serratiopeptidase is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

You can take Brodase-D Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take Brodase-D Tablet based on your medical condition. Brodase-D Tablet may have common side effects like stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects of Brodase-D Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Brodase-D Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. Brodase-D Tablet may be associated with a small increased risk of heart attack ‘myocardial infarction. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Brodase-D Tablet

Post-traumatic pain, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Brodase-D Tablet plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers which cause pain and fever. Brodase-D Tablet relieves pain and inflammation in arthritic conditions with the benefit of increased antibiotic penetration and micro-circulation at the injury site. Serratiopeptidase present in Brodase-D Tablet is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Brodase-D Tablet as it may lead to an increase in the risk of liver damage. Patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, and hypertension (high blood pressure), should not take Brodase-D Tablet . Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to pain killers and, complications like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Brodase-D Tablet . Do not drive or operate heavy machinery as intake of Brodase-D Tablet may cause dizziness. Patients who had recently undergone heart bypass surgery should take Brodase-D Tablet with caution and only under medical supervision. Use of Brodase-D Tablet is contraindicated in kidney failure patients or who are undergoing dialysis.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Brodase-D Tablet:
Co-administration of Brodase-D Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Brodase-D Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Brodase-D Tablet:
Concomitant use of Brodase-D Tablet with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking Brodase-D Tablet with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Brodase-D Tablet:
Co-administration of Brodase-D Tablet and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Brodase-D Tablet and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Brodase-D Tablet:
Co-administration of Brodase-D Tablet with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Brodase-D Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacPonatinib
Severe
How does the drug interact with Brodase-D Tablet:
Taking Brodase-D Tablet with Ponatinib can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Brodase-D Tablet and Ponatinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Brodase-D Tablet:
Co-administration of Brodase-D Tablet and Apixaban may raise the risk of stomach bleeding.

How to manage the interaction:
Although there is a interaction between Brodase-D Tablet and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Brodase-D Tablet:
Co-administration use of Brodase-D Tablet with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Brodase-D Tablet may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Brodase-D Tablet:
Concomitant administration of Brodase-D Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Brodase-D Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Brodase-D Tablet:
Taking Brodase-D Tablet with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Brodase-D Tablet and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Brodase-D Tablet:
Coadministration of Brodase-D Tablet with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between Brodase-D Tablet and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead you can do stretching, low impact aerobic exercise like walking on treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit little as possible, and only for short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a foot rest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Brodase-D Tablet when taken by patients who are allergic to pain-killers can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.

You should only take Brodase-D Tablet if doctor has prescribed you. The maximum recommended dose of Brodase-D Tablet is twice daily. Brodase-D Tablet can be one in the morning and one in the evening.

Rheutamoid arthritis is an autoimmune disease that causes chronic inflammation and pain of the joints.

Ankylosing spondylitis is a arthritis of the spine which can lead to the fusion of the vertebrae, lead to pain and inflammation in the spine.

Yes, Brodase-D Tablet can cause stomach upset. So, it should be preferably taken with food to avoid it.

Drug-Drug Interactions Checker List

  • NIMESULIDE
  • OXYPHENBUTAZONE
  • METAMIZOLE
  • METHOTREXATE
  • WARFARIN

Disease/Condition Glossary

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation are caused due to sprains, strains, trauma or post-surgery. These types of injuries may require a prolonged amount of time to heal.

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