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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Oscar Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Clopirel-Plus Tablet

Clopirel-Plus Tablet belongs to the class of antiplatelet drugs used for the prevention of heart attack and stroke. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is most often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

Clopirel-Plus Tablet is composed of two medicines, namely: Aspirin and Clopidogrel. These are blood thinners (anti-platelet) that prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Clopirel-Plus Tablet helps in the free flow of blood, thereby preventing a heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of lungs).

Your doctor will advise you on how often you take your tablets based on your medical condition. The common side effects of Clopirel-Plus Tablet include abdominal pain, indigestion, diarrhoea, easy bruising, and nosebleeds. Clopirel-Plus Tablet is known to cause dizziness and blurry vision, so driving should be avoided. Most of these side effects of Clopirel-Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping Clopirel-Plus Tablet may worsen your condition and increase the risk of a future heart attack. Let your doctor know if are sensitive to clopidogrel or aspirin, have kidney/liver diseases, bleeding issues (like peptic ulcer, brain haemorrhage), pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Clopirel-Plus Tablet before any surgery is scheduled or any new medicine is taken. 

Uses of Clopirel-Plus Tablet

Prevention of heart attack and stroke.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Clopirel-Plus Tablet is composed of Aspirin and Clopidogrel, which act as blood thinners (anti-platelet) and prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Clopirel-Plus Tablet helps in the free flow of blood, thereby preventing heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of lungs).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

You should avoid taking Clopirel-Plus Tablet if you are allergic to Clopirel-Plus Tablet . Let your doctor know if you have a medical condition that is causing bleeding such as a haemophilia, stomach ulcer or bleeding within your head or bowel. Caution is required before giving Clopirel-Plus Tablet to the liver or kidney problems patients. People affected with respiratory problems like asthma, rhinitis or nasal polyps should consult a doctor before intake of Clopirel-Plus Tablet . Clopirel-Plus Tablet is not recommended for the breastfeeding mother as it passes into the breast milk. The safety and effectiveness of Clopirel-Plus Tablet in children less than 12 years of age have not been established. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Clopirel-Plus Tablet:
Combining Ketorolac tromethamine with Clopirel-Plus Tablet can increase the risk of adverse effects.

How to manage the interaction:
Taking Clopirel-Plus Tablet with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Clopirel-Plus Tablet:
Co-administration of Ketorolac and Clopirel-Plus Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Clopirel-Plus Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Clopirel-Plus Tablet:
Taking Clopirel-Plus Tablet together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Clopirel-Plus Tablet with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Clopirel-Plus Tablet:
When Selexipag and Clopirel-Plus Tablet are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Clopirel-Plus Tablet with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
AspirinOmacetaxine mepesuccinate
Severe
How does the drug interact with Clopirel-Plus Tablet:
Using omacetaxine together with Clopirel-Plus Tablet may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Clopirel-Plus Tablet and Omacetaxine mepesuccinate, you can take these medicines together if prescribed by a doctor. It is important to closely monitor for any signs of bleeding during the treatment and contact a doctor right away if you experience symptoms like bruising, dizziness, or severe headache. Other symptoms to watch out for include red or black stools, weakness, and vomiting. Do not stop using any medications without talking to a doctor.
How does the drug interact with Clopirel-Plus Tablet:
Coadministration of Clopirel-Plus Tablet and Teriflunomide can enhance the risk of liver problems.

How to manage the interaction:
Although co-administration of Clopirel-Plus Tablet with teriflunomide can lead to an interaction, it can be taken if recommended by a doctor. If you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clopirel-Plus Tablet:
When regorafenib is used with Clopirel-Plus Tablet, the risk of bleeding may increase.

How to manage the interaction:
Although there is a possible interaction between Clopirel-Plus Tablet and regorafenib, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Clopirel-Plus Tablet:
Taking Clopirel-Plus Tablet with ibuprofen may impair the efficacy of Clopirel-Plus Tablet and increase the risk of developing stomach ulcers and bleeding.

How to manage the interaction:
Although there is a possible interaction between Clopirel-Plus Tablet and ibuprofen, you can take these medicines together if prescribed by a doctor. However, if you experience severe stomach discomfort, bloating, sudden dizziness or lightheadedness, nausea, vomiting (particularly with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Clopirel-Plus Tablet:
Coadministration of warfarin with Clopirel-Plus Tablet may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Clopirel-Plus Tablet and warfarin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Clopirel-Plus Tablet:
Combined use of Clopirel-Plus Tablet with ramucirumab may result in gut ulcers and bleeding.

How to manage the interaction:
There may be a possibility of interaction between Clopirel-Plus Tablet and Ramucirumab, but it can be taken if prescribed by a doctor. However, if you notice unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Clopirel-Plus Tablet .
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Clopirel-Plus Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Clopirel-Plus Tablet consists Aspirin and Clopidogrel. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).

Please consult your doctor if Clopirel-Plus Tablet needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Clopirel-Plus Tablet a few days before surgery since it can cause an increased risk of bleeding during surgery.

Clopirel-Plus Tablet consists of Aspirin and Clopidogrel. These are blood-thinning agents and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

Clopirel-Plus Tablet is generally safe to take for a long time. It works best if you take it for many months or even years. If you're at risk of getting a stomach ulcer, your doctor may prescribe a medicine to treat ulcer, while you're taking Clopirel-Plus Tablet .

Drug-Drug Interactions Checker List

  • WARFARIN
  • HEPARIN
  • FLUOXETINE
  • LITHIUM
  • GLIBENCLAMIDE
  • REPAGLINIDE
  • METHOTREXATE
  • VALPROATE
  • PHENYTOIN
  • IBUPROFEN
  • OMEPRAZOLE
  • FLUCONAZOLE
  • RITONAVIR
  • COBICISTAT
  • PROBENECID

Special Advise

Let your doctor know that you are using Clopirel-Plus Tablet if you have a scheduled surgery since this medicine may increase the risk of bleeding.

Disease/Condition Glossary

A blood clot is a clump or aggregation of blood that changes from a liquid to a gel-like state. Clotting is a natural process that prevents you from losing too much blood in an accident, trauma, surgery or cut. When a clot forms inside the veins, it won’t always dissolve on its own and can become even life-threatening situation.

Stroke: When our brain does not get sufficient oxygen and blood supply, it starts dying within a few minutes leading to a heart attack or stroke.

Heart attack: It occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is most often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). During a heart attack (myocardial infarction), the blood supply which nourishes the heart with oxygen is cut off. This causes the heart muscle to die. Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

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