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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

TACROLIMUS-1MG

Manufacturer/Marketer

Cognitus Life Sciences Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Cograf-1 Capsule 10's

Cograf-1 Capsule 10's belongs to a class of drugs called immunosuppressants used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. Organ rejection occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Cograf-1 Capsule 10's contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. Thus, prevents organ rejection in transplanted patients and helps the body in accepting the new organ.

Take Cograf-1 Capsule 10's as prescribed. You are advised to use Cograf-1 Capsule 10's for as long as your doctor has recommended it for you based on your medical condition. Some people may experience nausea, diarrhoea, headache, kidney problems, infection, fever, constipation or high blood pressure. Most of these side effects of Cograf-1 Capsule 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tacrolimus or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Cograf-1 Capsule 10's. Avoid alcohol consumption with Cograf-1 Capsule 10's. Drive only if you are alert, as Cograf-1 Capsule 10's may cause some people vision problems or nervous disturbances. If you are about to get vaccinated, inform your doctor before taking Cograf-1 Capsule 10's. Cograf-1 Capsule 10's may increase the risk of infections or skin cancer as it lowers the body’s immune defence system.

Uses of Cograf-1 Capsule 10's

Prevent transplanted organ rejection

Directions for Use

Capsule: Take the capsule as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.Granules: The granules should be mixed with water to make an oral suspension. Drink the prepared suspension immediately. Do not save the suspension for later use.

Medicinal Benefits

Cograf-1 Capsule 10's contains Tacrolimus, an immunosuppressant used to prevent organ rejection after a transplant. Cograf-1 Capsule 10's suppresses the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cograf-1 Capsule 10's

  • Nausea
  • Diarrhoea
  • Headache
  • Kidney problems
  • Infection
  • Constipation
  • Fever
  • High blood pressure

Drug Warnings

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Cograf-1 Capsule 10's. Avoid alcohol consumption with Cograf-1 Capsule 10's. Drive only if you are alert, as Cograf-1 Capsule 10's may cause vision problems or nervous disturbances in some people. If you are about to get vaccinated, inform your doctor before taking Cograf-1 Capsule 10's. Cograf-1 Capsule 10's may increase the risk of infections or skin cancer as it lowers the body’s immune defence system. While taking Cograf-1 Capsule 10's, you are advised to wear protective clothing and sunscreen while going out. You are recommended to use glass or metal materials to prepare the oral suspension. Avoid using plastic (PVC) materials to prepare the suspension as the granules will stick to a plastic container, and your child may not receive their full dose. Do not inhale or let the granules or prepared oral suspension come in contact with your skin or eyes. In case of accidental contact with skin, wash the area well with soap and water, and if it comes in contact with the eyes, rinse with plain water.

Diet & Lifestyle Advise

Kidney transplant:

  • Include fruits and vegetables in your daily routine.
  • Follow a vitamin-C-rich diet.
  • Reduce salt intake.
  • Eat a handful of walnuts and almonds every day.
  • Reduce intake of unhealthy cholesterol and fats.
  • Consume dark chocolate with at least 70% cocoa.

Liver and Heart transplant:

  • Eat whole-grain bread, cereals and other grains, fruits and vegetables, lean meats, fish and poultry.
  • Maintain a low-fat and low-salt diet.
  • Drink low-fat milk or eat other low-fat dairy products to maintain adequate calcium.
  • Stay hydrated by drinking sufficient water and other fluids.
  • Avoid alcohol consumption.
  • Avoid grapefruit and grapefruit juice. 

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Cograf-1 Capsule 10's Substitute

Substitutes safety advice
  • Prograf 1 mg Capsule 10's

    by Others

    40.28per tablet
  • Tacsant 1 mg Capsule 10's

    by Others

    37.88per tablet
  • Pangraf 1 Capsule 10's

    by Others

    40.91per tablet
  • Tacrograf 1 Capsule 10's

    by Others

    45.40per tablet
  • Advagraf 1mg Capsule 10's

    by Others

    90.00per tablet

Author Details

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FAQs

Cograf-1 Capsule 10's contains Tacrolimus, an immunosuppressant that works by the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Cograf-1 Capsule 10's may increase the risk of infections as it may weaken the immune system. Therefore, consult a doctor immediately if you have any signs of infection, such as sore throat or fever.

Cograf-1 Capsule 10's may increase the risk of skin cancer. Therefore, avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella (MMR), oral polio, varicella, yellow fever, intranasal influenza, BCG and TY21a typhoid vaccines, inform your doctor that you are taking Cograf-1 Capsule 10's because it may reduce the effectiveness of the vaccine and increase your risk of contracting the infection that the vaccine is meant to protect against.

Using Cograf-1 Capsule 10's with Sirolimus is not recommended in patients who have had heart or liver transplants. It is unknown if kidney transplant recipients can use it safely. Hence, please seek medical advice before combining Cograf-1 Capsule 10's with other medications.

Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • SIROLIMUS
  • NELFINAVIR
  • PHENYTOIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TRIAMTERENE
  • AMILORIDE

Special Advise

Regular blood tests and certain other tests are recommended while taking Cograf-1 Capsule 10's to check blood sugar levels, kidney functioning and potassium levels in the blood.

Disease/Condition Glossary

Organ rejection: It occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it. Organ rejection may be hyperacute (occurs in minutes to hours), acute (occurs within the first few months), or chronic (occurs after a year or anytime beyond). The symptoms of organ rejection may vary based on the type of organ transplant you have had. However, if you experience pain, fever, or other signs of illness, contact your doctor immediately.

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