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Composition :

DABIGATRAN-110MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dabirex-110 Capsule

Dabirex-110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.

Dabirex-110 Capsule contains ‘Dabigatran’, which works by inhibiting the production of clotting factors Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easy through your veins, making it less likely to form a serious blood clot. So, an intake of Dabirex-110 Capsule helps prevent blood clots if you have an increased risk of having a heart attack, or stroke.

Take Dabirex-110 Capsule as prescribed by your doctor. You are advised to take Dabirex-110 Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), and nausea, stomach pain, indigestion. Most of these side effects of Dabirex-110 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Dabirex-110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabirex-110 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabirex-110 Capsule . Try not to stop taking this medicine of your own. Stopping a sudden intake of Dabirex-110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke.

Uses of Dabirex-110 Capsule

Prevention of stroke, Prevention of heart attack

Directions for Use

Swallow Dabirex-110 Capsule as a whole with water; do not crush or chew it.

Medicinal Benefits

Dabirex-110 Capsule belongs to a class of drugs known as anticoagulants or blood thinner. It prevents clot formation in the deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain), and heart in patients with atrial fibrillation (irregular heart rhythm). Dabirex-110 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Dabirex-110 Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dabirex-110 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • You can take your medicine with meals to lower the chances of getting stomach pain.
  • Avoid foods that are acidic, spicy, sugary, or greasy.
  • Eat foods that are easily digestible such as rice, toast, and bananas.
  • Eat your meals in smaller amounts throughout the day to prevent strain on your stomach and digestion.
  • Drink water or fluids to stay hydrated and prevent stomach upset.
  • Use a heating pad or massage your stomach area.
  • Engage in mild physical activities such as yoga and walking.

Drug Warnings

If you are known to be allergic to Dabirex-110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabirex-110 Capsule . Safety and effectiveness of Dabirex-110 Capsule have not been established, so its use should be avoided in pediatric patients or children less than 18 years of age. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabirex-110 Capsule . Try not to stop taking Dabirex-110 Capsule of your own. Stopping a sudden intake of Dabirex-110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Hence, you should consult a doctor before stopping the dose of Dabirex-110 Capsule . You should inform the doctor that you are taking Dabirex-110 Capsule before any surgery is scheduled. Dabirex-110 Capsule can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Avoid consumption of alcohol while taking Dabirex-110 Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dabirex-110 Capsule:
When Mifepristone is taken with Dabirex-110 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabirex-110 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dabirex-110 Capsule:
Taking Dabirex-110 Capsule with Urokinase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabirex-110 Capsule with Urokinase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabirex-110 Capsule:
Taking Flurbiprofen with Dabirex-110 Capsule can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Flurbiprofen and Dabirex-110 Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience bleeding, feeling dizzy or lightheaded, dark or sticky stools, throwing up blood, severe headache, or feeling weak contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Dabirex-110 Capsule:
Co-administration of dabigatron etexilate with ciclosporin may increase the blood levels of dabigatron etexilate.

How to manage the interaction:
Although there is a possible interaction between dabigatron etexilate and ciclosporin, you can take these medicines together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms such as bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Dabirex-110 Capsule:
Taking Dabirex-110 Capsule with Defibrotide can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabirex-110 Capsule with Defibrotide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabirex-110 Capsule:
Taking Dabirex-110 Capsule with Acalabrutinib can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabirex-110 Capsule with Acalabrutinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabirex-110 Capsule:
Taking Verapamil with Dabirex-110 Capsule may increase the blood levels and effects of dabigatran. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Dabirex-110 Capsule and Verapamil together may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience paleness of skin, fatigue, dizziness, fainting, unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, or weakness. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Dabirex-110 Capsule:
Using dabigatran together with ketorolac may increase the risk of bleeding.

How to manage the interaction:
Although taking Ketorolac and Dabirex-110 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor.
How does the drug interact with Dabirex-110 Capsule:
Taking Dabirex-110 Capsule with rifampicin can decrease the blood levels of Dabirex-110 Capsule, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Dabirex-110 Capsule and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dabirex-110 Capsule:
Phenobarbital can drastically lower Dabirex-110 Capsule blood levels, making the medicine less effective in treating and preventing blood clots.

How to manage the interaction:
Although taking phenobarbital with Dabirex-110 Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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DABIGATRAN-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabirex-110 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabirex-110 Capsule treatment.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Dabirex-110 Capsule .
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to stop taking Dabirex-110 Capsule without consulting your doctor to worsen the condition. Therefore, take Dabirex-110 Capsule for as long as your doctor has prescribed it.

Please consult your doctor if Dabirex-110 Capsule needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Dabirex-110 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery. It also causes a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural). This type of blood clot could cause long-term paralysis.

Dabirex-110 Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. It is advisable, please consult your doctor and take Dabirex-110 Capsule for as long as your doctor has prescribed it.

Taking Dabirex-110 Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Dabirex-110 Capsule .

Dabirex-110 Capsule consists of Dabigatran is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENPROCOUMON
  • ACENOCOUMAROL
  • HEPARIN
  • CLOPIDOGREL
  • PRASUGREL
  • TICAGRELOR
  • RIVAROXABAN
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • VERAMAPIL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • TACROLIMUS
  • CYCLOSPORINE
  • LOPINAVIR
  • RITONAVIR
  • GLECAPREVIR
  • PIBRENTASVIR
  • RIFAMPICIN
  • CLARITHROMYCIN
  • ASPIRIN
  • IBUPROFEN
  • DICLOFENAC
  • CARBAMAZEPINE
  • PHENYTOIN

Special Advise

You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR, or international normalized ratio to analyze your blood clotting time.

Disease/Condition Glossary

A blood clot can occur in any part of the body that can lead to a heart attack, stroke, and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. On the other hand, deep vein thrombosis (blood clot in veins), peripheral artery disease (narrowed arteries due to fat deposit or blood clot), and atherosclerosis (fat build upon the walls of the arteries) can cause a blood clot in your limbs.

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