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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym

DAUNORUBICIN HYDROCHLORIDE

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Dauneon 20mg Injection 1 ml

Dauneon 20mg Injection 1 ml is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Dauneon 20mg Injection 1 ml helps to induce remission of nonlymphocytic leukemia (myelogenous, monocytic, erythroid) and acute lymphocytic leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

Dauneon 20mg Injection 1 ml contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Dauneon 20mg Injection 1 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Dauneon 20mg Injection 1 ml may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, fever, chills, and pain at the site of injection. Most of these side effects of Dauneon 20mg Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dauneon 20mg Injection 1 ml is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

Dauneon 20mg Injection 1 ml should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Dauneon 20mg Injection 1 ml. Dauneon 20mg Injection 1 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Dauneon 20mg Injection 1 ml as it may increase the risk of liver damage. This medicine may be recommended for use in children only if the benefits outweigh the risks.

Uses of Dauneon 20mg Injection 1 ml

lymphocytic leukemia, Acute non-lymphocytic leukemia

Directions for Use

Your doctor will administer Dauneon 20mg Injection 1 ml. Hence, do not self-administer.

Medicinal Benefits

Dauneon 20mg Injection 1 ml contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Dauneon 20mg Injection 1 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dauneon 20mg Injection 1 ml

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dizziness
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

Dauneon 20mg Injection 1 ml should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Dauneon 20mg Injection 1 ml. Dauneon 20mg Injection 1 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Dauneon 20mg Injection 1 ml as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Dauneon 20mg Injection 1 ml may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Dauneon 20mg Injection 1 ml as it may cause infections.

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
DaunorubicinCeritinib
Severe

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
How does the drug interact with Dauneon 20mg Injection 1 ml:
Taking Dauneon 20mg Injection 1 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dauneon 20mg Injection 1 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DaunorubicinCeritinib
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Taking Ceritinib with Dauneon 20mg Injection 1 ml may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Dauneon 20mg Injection 1 ml and Ceritinib, but it can be taken if prescribed by a doctor. If you have any symptoms like severe or long-lasting loose stools or vomiting, sudden dizziness or lightheadedness, fainting, difficulty breathing, or heart palpitations, consult a doctor. Don't hesitate to reach out to your doctor if you experience any of these symptoms. Do not discontinue any medications without first consulting your doctor.
DaunorubicinDisopyramide
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
The combined use of Dauneon 20mg Injection 1 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Dauneon 20mg Injection 1 ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DaunorubicinInfliximab
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Combining Infliximab with Dauneon 20mg Injection 1 ml can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Dauneon 20mg Injection 1 ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee contact a doctor right away. Do not stop using any medications without talking to a doctor.
DaunorubicinChloroquine
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Using chloroquine together with danorubicin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking chloroquine and Dauneon 20mg Injection 1 ml together can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DaunorubicinGatifloxacin
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Taking Dauneon 20mg Injection 1 ml with Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dauneon 20mg Injection 1 ml with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DaunorubicinBaricitinib
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Using baricitinib together with Dauneon 20mg Injection 1 ml may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Dauneon 20mg Injection 1 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
DaunorubicinClozapine
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
When Clozapine is taken with Dauneon 20mg Injection 1 ml, may increase the risk of infection and irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Dauneon 20mg Injection 1 ml and Clozapine, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include problems with your immune system, heart rhythm, or signs of infection like fever, chills, or a sore throat. Other symptoms to watch out for are muscle aches, difficulty breathing, unexplained weight loss, pain, sudden dizziness, feeling lightheaded, fainting, or heart palpitations. Do not stop using any medications without first talking to your doctor.
DaunorubicinIvabradine
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Using ivabradine together with Dauneon 20mg Injection 1 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Dauneon 20mg Injection 1 ml and Ivabradine together can cause an interaction, it can be taken if your doctor has suggested it. It is important to keep a close watch on your heart. If you have any of these symptoms - irregular heart rhythm, heart condition, long qt syndrome from birth, conduction problems, prolonged diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
DaunorubicinEfavirenz
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Taking Efavirenz with Dauneon 20mg Injection 1 ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz with Dauneon 20mg Injection 1 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Dauneon 20mg Injection 1 ml as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Dauneon 20mg Injection 1 ml Substitute

Substitutes safety advice
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  • Daunoplus 20Mg Inj

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • MESALAZINE
  • OLSALAZINE
  • SULFASALAZINE
  • GENTAMICIN
  • NEOMYCIN
  • AMIKACIN
  • CHOLERA VACCINE
  • TYPHOID VACCINE

Special Advise

  • Regular blood tests are recommended while taking Dauneon 20mg Injection 1 ml to monitor the number and type of cells in the blood and liver functioning.

Disease/Condition Glossary

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

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