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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym

DAUNORUBICIN HYDROCHLORIDE

Manufacturer/Marketer

Cipla Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About DAUNOTEC 20MG INJECTION

DAUNOTEC 20MG INJECTION is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. DAUNOTEC 20MG INJECTION helps to induce remission of nonlymphocytic leukemia (myelogenous, monocytic, erythroid) and acute lymphocytic leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

DAUNOTEC 20MG INJECTION contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, DAUNOTEC 20MG INJECTION stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

DAUNOTEC 20MG INJECTION may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, fever, chills, and pain at the site of injection. Most of these side effects of DAUNOTEC 20MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. DAUNOTEC 20MG INJECTION is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

DAUNOTEC 20MG INJECTION should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with DAUNOTEC 20MG INJECTION. DAUNOTEC 20MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with DAUNOTEC 20MG INJECTION as it may increase the risk of liver damage. This medicine may be recommended for use in children only if the benefits outweigh the risks.

Uses of DAUNOTEC 20MG INJECTION

lymphocytic leukemia, Acute non-lymphocytic leukemia

Directions for Use

Your doctor will administer DAUNOTEC 20MG INJECTION. Hence, do not self-administer.

Medicinal Benefits

DAUNOTEC 20MG INJECTION contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, DAUNOTEC 20MG INJECTION stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DAUNOTEC 20MG INJECTION

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dizziness
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

DAUNOTEC 20MG INJECTION should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with DAUNOTEC 20MG INJECTION. DAUNOTEC 20MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with DAUNOTEC 20MG INJECTION as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as DAUNOTEC 20MG INJECTION may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking DAUNOTEC 20MG INJECTION as it may cause infections.

Drug-Drug Interactions

verifiedApollotooltip
DaunorubicinZiprasidone
Critical
DaunorubicinBaricitinib
Severe

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
How does the drug interact with Daunotec 20mg Injection:
Taking Daunotec 20mg Injection with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Daunotec 20mg Injection with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DaunorubicinBaricitinib
Severe
How does the drug interact with Daunotec 20mg Injection:
Using baricitinib together with Daunotec 20mg Injection may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Daunotec 20mg Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
DaunorubicinThalidomide
Severe
How does the drug interact with Daunotec 20mg Injection:
Taking thalidomide together with Daunotec 20mg Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Daunotec 20mg Injection together can possibly result in an interaction, but it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
DaunorubicinEtanercept
Severe
How does the drug interact with Daunotec 20mg Injection:
When Etanercept is used with Daunotec 20mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Daunotec 20mg Injection and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
DaunorubicinMoxifloxacin
Severe
How does the drug interact with Daunotec 20mg Injection:
Using Moxifloxacin together with Daunotec 20mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Daunotec 20mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, or heart palpitations, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DaunorubicinInfliximab
Severe
How does the drug interact with Daunotec 20mg Injection:
Combining Infliximab with Daunotec 20mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Daunotec 20mg Injection, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee contact a doctor right away. Do not stop using any medications without talking to a doctor.
DaunorubicinGatifloxacin
Severe
How does the drug interact with Daunotec 20mg Injection:
Taking Daunotec 20mg Injection with Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Daunotec 20mg Injection with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DaunorubicinIvabradine
Severe
How does the drug interact with Daunotec 20mg Injection:
Using ivabradine together with Daunotec 20mg Injection can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Daunotec 20mg Injection and Ivabradine together can cause an interaction, it can be taken if your doctor has suggested it. It is important to keep a close watch on your heart. If you have any of these symptoms - irregular heart rhythm, heart condition, long qt syndrome from birth, conduction problems, prolonged diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
DaunorubicinCeritinib
Severe
How does the drug interact with Daunotec 20mg Injection:
Taking Ceritinib with Daunotec 20mg Injection may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Daunotec 20mg Injection and Ceritinib, but it can be taken if prescribed by a doctor. If you have any symptoms like severe or long-lasting loose stools or vomiting, sudden dizziness or lightheadedness, fainting, difficulty breathing, or heart palpitations, consult a doctor. Don't hesitate to reach out to your doctor if you experience any of these symptoms. Do not discontinue any medications without first consulting your doctor.
DaunorubicinHydroxychloroquine
Severe
How does the drug interact with Daunotec 20mg Injection:
The combined use of Daunotec 20mg Injection and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Daunotec 20mg Injection and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking DAUNOTEC 20MG INJECTION as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

DAUNOTEC 20MG INJECTION Substitute

Substitutes safety advice
  • Dauneon 20mg Injection 1 ml

    by Others

    283.50per tablet
  • Daunomycin 20Mg Inj

    by AYUR

    359.03per tablet
  • Daunorubitec 20Mg Inj

    by AYUR

    280.80per tablet
  • Daunoplus 20Mg Inj

    by AYUR

    271.80per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • MESALAZINE
  • OLSALAZINE
  • SULFASALAZINE
  • GENTAMICIN
  • NEOMYCIN
  • AMIKACIN
  • CHOLERA VACCINE
  • TYPHOID VACCINE

Special Advise

  • Regular blood tests are recommended while taking DAUNOTEC 20MG INJECTION to monitor the number and type of cells in the blood and liver functioning.

Disease/Condition Glossary

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

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