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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym :

DAUNORUBICIN HYDROCHLORIDE

Composition :

DAUNORUBICIN-20MG

Manufacturer/Marketer :

Vhb Life Sciences Inc

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Daunoplus 20Mg Inj

Daunoplus 20Mg Inj is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Daunoplus 20Mg Inj helps to induce remission of nonlymphocytic leukemia (myelogenous, monocytic, erythroid) and acute lymphocytic leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

Daunoplus 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunoplus 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Daunoplus 20Mg Inj may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, fever, chills, and pain at the site of injection. Most of these side effects of Daunoplus 20Mg Inj do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Daunoplus 20Mg Inj is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

Daunoplus 20Mg Inj should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunoplus 20Mg Inj. Daunoplus 20Mg Inj is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunoplus 20Mg Inj as it may increase the risk of liver damage. This medicine may be recommended for use in children only if the benefits outweigh the risks.

Uses of Daunoplus 20Mg Inj

lymphocytic leukemia, Acute non-lymphocytic leukemia

Directions for Use

Your doctor will administer Daunoplus 20Mg Inj. Hence, do not self-administer.

Medicinal Benefits

Daunoplus 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunoplus 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Daunoplus 20Mg Inj
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Exercise regularly and maintain a healthy weight.
  • Manage cholesterol and blood pressure.
  • Limit intake of caffeine and alcohol.
  • Avoid vaping and tobacco smoke.
  • Get enough sleep.
  • Talk to your doctor about antiarrhythmic drugs or other medications to treat your condition.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Drug Warnings

Daunoplus 20Mg Inj should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunoplus 20Mg Inj. Daunoplus 20Mg Inj is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunoplus 20Mg Inj as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Daunoplus 20Mg Inj may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Daunoplus 20Mg Inj as it may cause infections.

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
DaunorubicinClozapine
Severe

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
How does the drug interact with Daunoplus 20Mg Inj:
Taking Daunoplus 20Mg Inj with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Daunoplus 20Mg Inj with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DaunorubicinClozapine
Severe
How does the drug interact with Daunoplus 20Mg Inj:
When Clozapine is taken with Daunoplus 20Mg Inj, may increase the risk of infection and irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Daunoplus 20Mg Inj and Clozapine, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include problems with your immune system, heart rhythm, or signs of infection like fever, chills, or a sore throat. Other symptoms to watch out for are muscle aches, difficulty breathing, unexplained weight loss, pain, sudden dizziness, feeling lightheaded, fainting, or heart palpitations. Do not stop using any medications without first talking to your doctor.
DaunorubicinCladribine
Severe
How does the drug interact with Daunoplus 20Mg Inj:
The combined use of cladribine with Daunoplus 20Mg Inj can increase the risk of serious infections.

How to manage the interaction:
Taking Daunoplus 20Mg Inj with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without talking to a doctor.
DaunorubicinEtanercept
Severe
How does the drug interact with Daunoplus 20Mg Inj:
When Etanercept is used with Daunoplus 20Mg Inj, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Daunoplus 20Mg Inj and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
DaunorubicinNilotinib
Severe
How does the drug interact with Daunoplus 20Mg Inj:
Coadministration of Daunoplus 20Mg Inj and Nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Daunoplus 20Mg Inj and Nilotinib together can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like sudden dizziness, shortness of breath, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DaunorubicinTofacitinib
Severe
How does the drug interact with Daunoplus 20Mg Inj:
When Tofacitinib is taken with Daunoplus 20Mg Inj, it may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Daunoplus 20Mg Inj, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
DaunorubicinIvabradine
Severe
How does the drug interact with Daunoplus 20Mg Inj:
Using ivabradine together with Daunoplus 20Mg Inj can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Daunoplus 20Mg Inj and Ivabradine together can cause an interaction, it can be taken if your doctor has suggested it. It is important to keep a close watch on your heart. If you have any of these symptoms - irregular heart rhythm, heart condition, long qt syndrome from birth, conduction problems, prolonged diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
DaunorubicinAmiodarone
Severe
How does the drug interact with Daunoplus 20Mg Inj:
Coadministration of Daunoplus 20Mg Inj with amiodarone may increase the risk of abnormal cardiac rhythms.

How to manage the interaction:
Although taking Daunoplus 20Mg Inj with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor . Do not stop taking any medications without visiting a doctor.
DaunorubicinBaricitinib
Severe
How does the drug interact with Daunoplus 20Mg Inj:
Using baricitinib together with Daunoplus 20Mg Inj may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Daunoplus 20Mg Inj if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
DaunorubicinEfavirenz
Severe
How does the drug interact with Daunoplus 20Mg Inj:
Taking Efavirenz with Daunoplus 20Mg Inj can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz with Daunoplus 20Mg Inj together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Daunoplus 20Mg Inj as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Daunoplus 20Mg Inj Substitute

Substitutes safety advice
  • Daunomycin 20Mg Inj

    by AYUR

    351.05per tablet
  • Daunorubitec 20Mg Inj

    by AYUR

    280.80per tablet
  • DAUNOTEC 20MG INJECTION

    by Others

    269.90per tablet
  • Dauneon 20mg Injection 1 ml

    by Others

    283.50per tablet
  • Daunocyte 20 mg Injection 1's

    by Others

    285.80per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Daunoplus 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Daunoplus 20Mg Inj may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Daunoplus 20Mg Inj if you are planning to become a parent.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Daunoplus 20Mg Inj as it may cause infections.

Drug-Drug Interactions Checker List

  • MESALAZINE
  • OLSALAZINE
  • SULFASALAZINE
  • GENTAMICIN
  • NEOMYCIN
  • AMIKACIN
  • CHOLERA VACCINE
  • TYPHOID VACCINE

Special Advise

  • Regular blood tests are recommended while taking Daunoplus 20Mg Inj to monitor the number and type of cells in the blood and liver functioning.

Disease/Condition Glossary

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

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