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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

PIROXICAM-40MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Doloforce Injection 4 x 2 ml

Doloforce Injection 4 x 2 ml belongs to the group of medications known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms like pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.

Doloforce Injection 4 x 2 ml contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Doloforce Injection 4 x 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as injection site reactions, diarrhoea, dizziness, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

Doloforce Injection 4 x 2 ml may increase the risk of heart attack and the chances of stomach ulcers and bleeding. If you have had any recent heart bypass surgery, do not take Doloforce Injection 4 x 2 ml unless prescribed by the doctor. Consult your doctor before taking Doloforce Injection 4 x 2 ml if you are pregnant or breastfeeding. Doloforce Injection 4 x 2 ml may cause dizziness, so drive with caution. Doloforce Injection 4 x 2 ml is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Doloforce Injection 4 x 2 ml as it could lead to increased drowsiness and dizziness. It could also increase the risk of stomach bleeding.

Uses of Doloforce Injection 4 x 2 ml

Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis

Directions for Use

Doloforce Injection 4 x 2 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Doloforce Injection 4 x 2 ml belongs to the group of pain killers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to treat musculoskeletal pain. It is also used to relieve symptoms associated with osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain. Doloforce Injection 4 x 2 ml works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Doloforce Injection 4 x 2 ml

  • Injection site reactions
  • Diarrhoea
  • Dizziness
  • Nausea
  • Vomiting
  • Stomach pain

Drug Warnings

Doloforce Injection 4 x 2 ml may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking Doloforce Injection 4 x 2 ml. Besides this, Doloforce Injection 4 x 2 ml may also cause stomach and intestinal bleeding/ulcers, so let your doctor know if you have these problems. Do not take Doloforce Injection 4 x 2 ml if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase the risk of a heart attack. Consult your doctor before taking Doloforce Injection 4 x 2 ml if you are pregnant or breastfeeding. Doloforce Injection 4 x 2 ml may cause dizziness, so drive only if you are alert. Doloforce Injection 4 x 2 ml is not recommended for children as safety has not been established. Avoid consuming alcohol along with Doloforce Injection 4 x 2 ml as it could lead to increased dizziness and may increase the risk of stomach bleeding. Inform your doctor before taking Doloforce Injection 4 x 2 ml if you have asthma, water retention (oedema) or high blood pressure, stuffy/runny nose, nasal polyps, liver or kidney problems.

Drug-Drug Interactions

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PiroxicamCidofovir
Critical
PiroxicamKetorolac tromethamine
Critical

Drug-Drug Interactions

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PiroxicamCidofovir
Critical
How does the drug interact with Doloforce Injection 4 x 2 ml:
Co-administration of Cidofovir with Doloforce Injection 4 x 2 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Doloforce Injection 4 x 2 ml with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamKetorolac tromethamine
Critical
How does the drug interact with Doloforce Injection 4 x 2 ml:
Using ketorolac tromethamine together with Doloforce Injection 4 x 2 ml may increase the risk of side effects.

How to manage the interaction:
Taking Doloforce Injection 4 x 2 ml with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
PiroxicamApixaban
Severe
How does the drug interact with Doloforce Injection 4 x 2 ml:
Coadministration of Doloforce Injection 4 x 2 ml and Apixaban may raise the risk of bleeding.

How to manage the interaction:
Combination of Doloforce Injection 4 x 2 ml and Apixaban may cause an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
PiroxicamMeloxicam
Severe
How does the drug interact with Doloforce Injection 4 x 2 ml:
Taking Doloforce Injection 4 x 2 ml with Meloxicam together can increase the risk of side effects inflammation(swelling with redness and pain), bleeding, ulceration, and perforation.

How to manage the interaction:
There may be a possibility of interaction between Doloforce Injection 4 x 2 ml and Meloxicam, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamKetoprofen
Severe
How does the drug interact with Doloforce Injection 4 x 2 ml:
Coadministration of Doloforce Injection 4 x 2 ml with Ketoprofen can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Although there is a possible interaction between Doloforce Injection 4 x 2 ml and Ketoprofen, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamVorapaxar
Severe
How does the drug interact with Doloforce Injection 4 x 2 ml:
Coadministration of Doloforce Injection 4 x 2 ml with Vorapaxar can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Doloforce Injection 4 x 2 ml and Vorapaxar, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamPanobinostat
Severe
How does the drug interact with Doloforce Injection 4 x 2 ml:
Using panobinostat together with Doloforce Injection 4 x 2 ml may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Doloforce Injection 4 x 2 ml and Panobinostat, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamMethotrexate
Severe
How does the drug interact with Doloforce Injection 4 x 2 ml:
Coadministration of Methotrexate with Doloforce Injection 4 x 2 ml can increase the levels and side effects.

How to manage the interaction:
Although there is a possible interaction between Doloforce Injection 4 x 2 ml and methotrexate, it can be taken if prescribed by a doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
PiroxicamNaproxen
Severe
How does the drug interact with Doloforce Injection 4 x 2 ml:
Coadministration of Naproxen and Doloforce Injection 4 x 2 ml can increase the risk or severity of stomach bleeding, inflammation(swelling with redness and pain), ulcers.

How to manage the interaction:
There may be a possible interaction between Naproxen and Doloforce Injection 4 x 2 ml, but they can be taken together if they are prescribed by doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.
PiroxicamValdecoxib
Severe
How does the drug interact with Doloforce Injection 4 x 2 ml:
Coadministration of Doloforce Injection 4 x 2 ml with Valdecoxib can increase the risk of side effects including inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Taking Doloforce Injection 4 x 2 ml with Valdecoxib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • METOPROLOL
  • CELECOXIB

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age; the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons might include a past injury such as torn cartilage, dislocated joints, and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, and tendons. It can be acute or chronic, can be localised or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure or injury to the bones, joints, tendons, muscles, and ligaments. Symptoms of musculoskeletal pain include stiffness, swelling, redness, muscle spasms or twitching, trouble moving the affected area, and soreness.

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