EMQUIN DS 500MG TABLET

Written By aquibnaseer ,

Reviewed By Sunny S , MBBS

MRP ₹7.9

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₹1.2 Cashback (15%)

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Prescription drug

Whats That

About EMQUIN DS 500MG TABLET

EMQUIN DS 500MG TABLET belongs to the class of medications called 'quinoline' primarily used to treat malaria. EMQUIN DS 500MG TABLET gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. EMQUIN DS 500MG TABLET is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis).

EMQUIN DS 500MG TABLET contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. EMQUIN DS 500MG TABLET prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

EMQUIN DS 500MG TABLET should be taken as prescribed by your doctor. The dose of EMQUIN DS 500MG TABLET can vary depending upon your condition and the severity of the infection. The common side effects of EMQUIN DS 500MG TABLET include vomiting, nausea, hair loss and itchy skin. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting EMQUIN DS 500MG TABLET, please inform your doctor if you are allergic to chloroquine or have kidney or liver problems. Do not take EMQUIN DS 500MG TABLET on your own. EMQUIN DS 500MG TABLET is safe to use during pregnancy and breastfeeding. Prolonged use of EMQUIN DS 500MG TABLET may have a severe risk on the heart and retina of the eyes leading to pounding heartbeats and permanent vision problems.

Uses of EMQUIN DS 500MG TABLET

Malaria, Intestinal amoebiasis, Rheumatoid arthritis

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

EMQUIN DS 500MG TABLET falls into a group of medicines known as antimalarials, indicated for treating or preventing malaria. EMQUIN DS 500MG TABLET contains chloroquine, which belongs to quinoline. It works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism. EMQUIN DS 500MG TABLET is also indicated for the treatment of rheumatoid arthritis and autoimmune diseases like lupus and intestinal infection caused by amoeba (amoebiasis).

Side effects of Emquin Ds 500mg Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Sleeplessness

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Depression

Managing depression as a side effect of medication: a comprehensive guide.

Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
Tell your doctor about your depression symptoms to adjust medication.
Consult a therapist or counsel for emotional support.
Engage in regular exercise to release endorphins (neurotransmitters).
Practice stress-reducing techniques like meditation and deep breathing.
Build a support network of friends, family, and support groups.
Establish a consistent sleep schedule.
Eat a nutritious diet rich in fruits, vegetables, and whole grains.
Limit or avoid alcohol and recreational substances.
Keep a mood journal to track symptoms and progress.

Drug Warnings

EMQUIN DS 500MG TABLET does not respond well against all malaria strains, so consult with your doctor if you do not respond well to EMQUIN DS 500MG TABLET. This medicine can affect heart health, especially if a person is taking medications, including the antibiotic azithromycin and anticancer like tamoxifen. An individual must consult with the doctor if they are noticing fast or pounding heartbeats and sudden dizziness. This medicine cannot be used for a long duration as it may cause irreversible damage to the eye that could lead to vision problems. EMQUIN DS 500MG TABLET cannot be used in persons who have heart disease, heart rhythm disorder, diabetes, a stomach disorder, an allergy to quinine, liver or kidney disease, psoriasis, alcoholism, porphyria (a genetic enzyme disorder that affects the skin or nervous system), a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Consult with your doctor if you are pregnant or breastfeeding as this medicine could only be used if prescribed by the doctor.

Drug-Drug Interactions

ChloroquineSparfloxacin

Critical

ChloroquineAuranofin

Critical

Drug-Drug Interactions

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ChloroquineSparfloxacin

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
Using Emquin Ds 500mg Tablet together with sparfloxacin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Emquin Ds 500mg Tablet with Sparfloxacin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.

ChloroquineAuranofin

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
Taking Auranofin with Emquin Ds 500mg Tablet can increase the risk of blood disorders and other severe side effects

How to manage the interaction:
Taking Auranofin with Emquin Ds 500mg Tablet is not recommended, as it may lead to an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.

ChloroquineCisapride

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
Taking Emquin Ds 500mg Tablet with Cisapride can increase the risk of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Emquin Ds 500mg Tablet with Cisapride is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.

ChloroquineDronedarone

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
When Emquin Ds 500mg Tablet is taken with Dronedarone, it may increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Emquin Ds 500mg Tablet with Dronedarone is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

ChloroquineZiprasidone

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
Taking Emquin Ds 500mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Emquin Ds 500mg Tablet with Ziprasidone is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.

ChloroquineAurothioglucose

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
Taking Aurothioglucose with Emquin Ds 500mg Tablet can cause blood disorders and other severe side effects

How to manage the interaction:
Taking Aurothioglucose with Emquin Ds 500mg Tablet is not recommended, as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.

ChloroquinePazopanib

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
Taking pazopanib with Emquin Ds 500mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Pazopanib with Emquin Ds 500mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

ChloroquineLevacetylmethadol

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
Using Levacetylmethadol together with Emquin Ds 500mg Tablet can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Emquin Ds 500mg Tablet with Levacetylmethadol is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

ChloroquineAgalsidase alfa

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
When Agalsidase alfa is used with Emquin Ds 500mg Tablet, it may decrease the effectiveness of the Agalsidase alfa.

How to manage the interaction:
Taking Agalsidase alfa with Emquin Ds 500mg Tablet is not recommended, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.

ChloroquineAgalsidase beta

Critical

How does the drug interact with Emquin Ds 500mg Tablet:
Using Emquin Ds 500mg Tablet with Agalsidase beta can reduce the effectiveness of agalsidase beta.

How to manage the interaction:
Taking Agalsidase beta with Emquin Ds 500mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Always take EMQUIN DS 500MG TABLET with meals for reduced gastric irritation.
Adequate nutrition is the key for improvement in malaria induced weakness.
It is important to allow the patient to eat regularly in small amounts to tolerate the food.
Increase fluid and protein intake for malaria induced weight loss.
Proper rest and mosquito-free premises is important for the patient to recover.

Side Effects of EMQUIN DS 500MG TABLET

Abnormal heart rhythm
Stomach pain
Nausea (being sick)
Diarrhoea
Loss of appetite
Headache
Skin rash
Liver problems

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

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Author Details

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:31 AM IST

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Drug-Diseases Interactions

CHLOROQUINE-500MGDisorders of porphyrin and bilirubin metabolism

Severe

CHLOROQUINE-500MGOther cardiac arrhythmias

Moderate

Drug-Diseases Interactions

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CHLOROQUINE-500MGDisorders of porphyrin and bilirubin metabolism

Severe

How does the disease interact with Emquin Ds 500mg Tablet:
Porphyria: In porphyria the use of Emquin Ds 500mg Tablet may aggravate this condition. Avoid Emquin Ds 500mg Tablet use until it is required.

How to manage the interaction:
If the risks aren't expected to outweigh the possible advantages, Emquin Ds 500mg Tablet shouldn't be utilized on these patients.

CHLOROQUINE-500MGOther cardiac arrhythmias

Moderate

How does the disease interact with Emquin Ds 500mg Tablet:
Arrhythmias:Emquin Ds 500mg Tablet has adverse effect like prolongation of QT interval, ventricular arrhythmias and torsades de pointes. Monitor ECG before initiation and during the therapy.

How to manage the interaction:
If you have sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat while taking these medications, whether they are taken together or separately, you should seek immediate assistance from a doctor. A close monitoring of ECG is required.

CHLOROQUINE-500MGEpilepsy

Moderate

How does the disease interact with Emquin Ds 500mg Tablet:
Seizures: Emquin Ds 500mg Tablet may cause epileptic seizures in susceptible patients. Administer Emquin Ds 500mg Tablet in patients with history of epilepsy.

How to manage the interaction:
In those who are vulnerable, Emquin Ds 500mg Tablet may result in epileptic fits. Patients who already have epileptic fits or have a low tolerance for seizures may be at greater risk.

CHLOROQUINE-500MGOther diseases of blood and blood-forming organs

Moderate

How does the disease interact with Emquin Ds 500mg Tablet:
Bone marrow suppression: With the use of Emquin Ds 500mg Tablet adverse effects such as neutropenia, agranulocytosis, aplastic anemia, and thrombocytopenia. In patients with preexisting bone marrow suppression use cautiously and monitor for complete blood count. Discontinue the Emquin Ds 500mg Tablet if any serious blood disorder is suspected.

How to manage the interaction:
It is important to inform your doctor if you have prior conditions like bone marrow suppression, a complete blood picture is advised to be taken if you are on a long term therapy with Emquin Ds 500mg Tablet. If you suspect any blood disorders, please inform it to your doctor immediately.

CHLOROQUINE-500MGOther hearing loss

Moderate

How does the disease interact with Emquin Ds 500mg Tablet:
Ototoxicity: Rarely, Emquin Ds 500mg Tablet was been associated with ototoxicity.The use of Emquin Ds 500mg Tablet has been associated rarely with ototoxicity. With long-term, high-dose Emquin Ds 500mg Tablet therapy which is irreversible nerve-type deafness may occur. In some patients with preexisting auditory damage, tinnitus, decrease in hearing may occur. Use with caution and discontinue therapy if new auditory defects occur or if hearing loss becomes worse.

How to manage the interaction:
If you any existing hearing damage, do not forget to inform it your doctor, so that a close monitoring can be done during the treatment with Emquin Ds 500mg Tablet.

CHLOROQUINE-500MGPsoriasis

Moderate

How does the disease interact with Emquin Ds 500mg Tablet:
In psoriasis patients, the Emquin Ds 500mg Tablet use may exacerbate severe attack of psoriasis. Do not use Emquin Ds 500mg Tablet unless the potential benefits vs risks outweighs.

How to manage the interaction:
It is important to tell your doctor if you have any existing skin conditions like psoriasis. Your doctor may prescribe the medication, if the benefits are more than the risks.

CHLOROQUINE-500MGMyasthenia gravis and other myoneural disorders

Moderate

How does the disease interact with Emquin Ds 500mg Tablet:
myasthenia gravis Use of Emquin Ds 500mg Tablet may exacerbate new onset of symptoms in patients with previously diagnosed myasthenia gravis. Use cautiously.

How to manage the interaction:
If you are suffering from myasthenia gravis, do not forget to tell it to your doctor. If you are taking Emquin Ds 500mg Tablet and experiencing symptoms like muscle weakness or weakness of the arms and legs, drooping of upper eyelid, difficulty speaking, difficulty swallowing, double vision, tiredness, or shortness of breath please inform your doctor.

FAQs

How does EMQUIN DS 500MG TABLET work?

EMQUIN DS 500MG TABLET works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism.

Can I take EMQUIN DS 500MG TABLET along with antibiotic?

The use of EMQUIN DS 500MG TABLET is not allowed in persons who are already taking any antibiotic (azithromycin) as it may cause dangerous effects on the heart.

Does EMQUIN DS 500MG TABLET cause insomnia or sleep cycle disturbance?

No such effect has been reported yet. Always consult your doctor for the change of dose regimen or an alternative medicine if needed.

Can EMQUIN DS 500MG TABLET be harmful if taken for long courses?

No such harmful interaction has been reported in patients who take this drug under strict doctors' surveillance. However, some patients might experience eye (retina) damage and cause pounding heart, so patient taking EMQUIN DS 500MG TABLET is advised to consult a doctor and have regular check-ups cyclically.

Is EMQUIN DS 500MG TABLET safe in G6PD deficiency?

There may be a risk of hemolysis in patients with G6PD deficiency while using EMQUIN DS 500MG TABLET. Doctor's consultation is mandatory before you start this medication.

Drug-Drug Interactions Checker List

PHENYLBUTAZONE
NEOSTIGMINE
PYRIDOSTIGMINE
AMPICILLIN
CIMETIDINE
TAMOXIFEN

Special Advise

Do not take EMQUIN DS 500MG TABLET if you have had a previous reaction to EMQUIN DS 500MG TABLET, or if you have certain eye problems involving your retina. Tell your healthcare provider about any problems you may have with your eyes.

Disease/Condition Glossary

Malaria: It is a severe & fatal parasitic infection caused by a protozoan called Plasmodium. 4 types of parasites can infect humans with malaria: Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. Female anopheles mosquito bites cause it. If bitten by an infected mosquito (the Anopheles mosquito), malaria parasites are injected into the blood. These parasites then migrate to the liver where they multiply via the bloodstream. A patient doesn't feel sick at this period because the parasites are in the liver. Then the parasites leave the liver and enter the red blood cells where the parasites are developing, and then the red blood cells burst, allowing them to transfer to another blood cell. The parasites release harmful chemicals into the bloodstream at this point, and the patient begins to feel ill. Malaria leads to periodic fever-chills, anaemia, kidney failure, and jaundice due to excessive red blood cell death due to plasmodium growth inside them.