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Composition :

EPLERENONE-25MG

Manufacturer/Marketer :

Chemo Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Epledart-25 Tablet

Epledart-25 Tablet belongs to a class of medicine called 'diuretics' (water pills) primarily used to treat hypertension (high blood pressure). It also maintains the bloodstream's potassium level, removes excess water from the body, and prevents hypertension (high blood pressure) due to oedema (fluid retention). Blood pressure measures the force our heart uses to pump blood to all body parts. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart.

Epledart-25 Tablet contains Eplerenone, which is prescribed for the treatment of hypertension. Epledart-25 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and the heart's workload, making it more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

Take Epledart-25 Tablet as prescribed by your doctor. Depending upon your medical condition, you are advised to take Epledart-25 Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid. Most of these side effects of Epledart-25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Epledart-25 Tablet of your own, as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Inform your doctor if you have any kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2, and patients with nil urine output (anuria). If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Epledart-25 Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to the Epledart-25 Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Please take Epledart-25 Tablet at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take Epledart-25 Tablet along with lithium to prevent serious side effects.

Uses of Epledart-25 Tablet

Hypertension (high blood pressure), Edema

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Epledart-25 Tablet  primarily used to treat hypertension (high blood pressure) and heart failure. It also treats edema (reduces swelling) caused due to other conditions. Epledart-25 Tablet works by increasing the amount of urine passing from the kidneys. It effectively reduces excess fluid levels in the body and reduces the heart's workload, and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

Storage

Store in a cool and dry place away from sunlight
Side effects of Epledart-25 Tablet
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.

Drug Warnings

Epledart-25 Tablet should not be given to the people allergic to Epledart-25 Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2 and patients with nil urine output (anuria), pregnant women, planning to get pregnant and breastfeeding women. Epledart-25 Tablet can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking Epledart-25 Tablet and breastfeeding. Dehydration with electrolyte and acid-base disturbances must be corrected before using Epledart-25 Tablet . Do not take extra potassium supplements or potassium-rich foods such as bananas and broccoli with Epledart-25 Tablet . It may lead to an excessive increase in blood potassium levels (hyperkalemia). Please take Epledart-25 Tablet at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take Epledart-25 Tablet along with lithium to prevent serious side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Epledart-25 Tablet:
Co-administration of Epledart-25 Tablet and Clarithromycin may significantly increase the blood levels and effects of Epledart-25 Tablet.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Clarithromycin with Epledart-25 Tablet is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
How does the drug interact with Epledart-25 Tablet:
Using Epledart-25 Tablet together with Potassium chloride may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking potassium chloride with Epledart-25 Tablet is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenonePotassium citrate
Critical
How does the drug interact with Epledart-25 Tablet:
Taking Epledart-25 Tablet with Potassium citrate may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Epledart-25 Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Epledart-25 Tablet:
The blood levels and effects of Epledart-25 Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Although there is a possible interaction between Epledart-25 Tablet and Itraconazole, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
How does the drug interact with Epledart-25 Tablet:
Coadministration of posaconazole with Epledart-25 Tablet can increase the blood levels of Epledart-25 Tablet. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between posaconazole and Epledart-25 Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epledart-25 Tablet:
Co-administration of Epledart-25 Tablet and Ritonavir may significantly increase the blood levels of Epledart-25 Tablet.

How to manage the interaction:
Taking Ritonavir and Epledart-25 Tablet together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Epledart-25 Tablet:
Coadministration of Ketoconazole with Epledart-25 Tablet can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking ketoconazole with Epledart-25 Tablet is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
EplerenonePotassium iodide
Critical
How does the drug interact with Epledart-25 Tablet:
Combining Epledart-25 Tablet with Potassium iodide may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium iodide and Epledart-25 Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Epledart-25 Tablet:
Combining Epledart-25 Tablet with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between spironolactone and Epledart-25 Tablet, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenoneSaquinavir
Critical
How does the drug interact with Epledart-25 Tablet:
Co-administration of EPELENONE and SAQUINAVIR may significantly increase the blood levels and side effects of Epledart-25 Tablet. This can increase the risk of serious side effects like high blood potassium, which in severe cases can lead to kidney failure, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Taking saquinavir and Epledart-25 Tablet together is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are highly antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid the consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • Elevate your legs or the swollen area on a chair or pillow.
  • Avoid standing or sitting for extended periods.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

DIURETIC

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Epledart-25 Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

It is not common, but Epledart-25 Tablet can sometimes increase the blood sugar level. Therefore, monitoring your blood sugar level to check for any fluctuations is crucial. Also, the use of Epledart-25 Tablet should be avoided in patients with type 2 diabetes and some kidney problems.

Yes, Epledart-25 Tablet can cause increased potassium levels (hyperkalemia), especially in patients with kidney problems or if you are taking potassium supplements along with Epledart-25 Tablet . Please monitor your electrolyte level regularly to avoid increased blood potassium levels.

It is a medical term for fluid retention or overload. Due to edema, the legs, hands, and other body parts start swelling, increasing blood pressure. If it does not subside, please consult your doctor immediately.

The main side effect of Epledart-25 Tablet is peeing (urination) more often than normal. Most people need to pee about 30 minutes after taking Epledart-25 Tablet and again within a few hours. Do not take Epledart-25 Tablet before going to bed, or you may have to wake up at night to go for urination frequently.

No, it is not recommended to take Epledart-25 Tablet along with lithium. It might increase lithium's level in the blood and lead to unpleasant side effects like visual impairment, loss of appetite, and muscle weakness. So, inform your doctor before starting Epledart-25 Tablet if you take lithium is recommended.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ASPIRIN
  • WARFARIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • CYCLOSPORINE
  • IBUPROFEN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR
  • NELFINAVIR
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • LITHIUM

Special Advise

  • Treatment with Epledart-25 Tablet requires regular monitoring of serum potassium and creatinine level.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Monitor your blood sugar level daily and if there is too much fluctuation, then immediately contact your doctor.

Disease/Condition Glossary

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

Oedema: Oedema, also known as fluid overload, occurs due to fluid build-up in spaces between the cells. Oedema can result from a variety of factors. Some oedema reasons are caused by your lifestyle, while an underlying medical problem causes others. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in hands or abdominal areas are the symptoms of oedema.

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