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Reviewed By Sunny S , MBBS
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Whats That

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Composition

DOMPERIDONE-30MG

Manufacturer/Marketer

Zeeford Life Sciences

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Esonip-DSR Capsule

Esonip-DSR Capsule belongs to a class of medications known as 'dopamine antagonist' used to treat nausea (feeling sick) and vomit (being sick) in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying).

Esonip-DSR Capsule contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Take Esonip-DSR Capsule as prescribed by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Esonip-DSR Capsule . However, if it does not resolve even after this, stop taking this medicine and contact the doctor. Do not take Esonip-DSR Capsule for longer than seven days. The most common side effect of Esonip-DSR Capsule is dry mouth. This side effect is temporary and may resolve after some time; however, if this side persists, contact the doctor.

Do not consume Esonip-DSR Capsule if you are hypersensitive to any components present in Esonip-DSR Capsule . Before taking the Esonip-DSR Capsule , inform your doctor if you suffer from liver or kidney problems. Prolonged intake of Esonip-DSR Capsule may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. Esonip-DSR Capsule is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Esonip-DSR Capsule .

Uses of Esonip-DSR Capsule

Nausea, Vomiting.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Oral Suspension/Syrup/Oral drops: Shake the bottle well before use. Check the label for directions and take Esonip-DSR Capsule in doses as prescribed by your doctor with the help of a measuring cup/dropper provided by the pack.

Medicinal Benefits

Esonip-DSR Capsule contains domperidone, a dopamine antagonist that helps by blocking certain vomiting-inducing receptors in the brain. Esonip-DSR Capsule also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and decreases gastric emptying time. Domperidone is occasionally used to boost milk production. If you're experiencing difficulty nursing, your doctor may prescribe it if nothing else has helped.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Esonip-DSR Capsule

  • Dry mouth
  • Headache

Drug Warnings

Do not consume Esonip-DSR Capsule if you are allergic to any components present in Esonip-DSR Capsule . Before taking the Esonip-DSR Capsule , contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure). Prolonged intake of Esonip-DSR Capsule may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. Tell your doctor if you are using anti-fungal medicines and/or if you have heart problems or AIDS/HIV. If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the Esonip-DSR Capsule , immediately contact your doctor. Domperidone is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Esonip-DSR Capsule .

Drug-Drug Interactions

verifiedApollotooltip
DomperidoneHalofantrine
Severe
DomperidoneNefazodone
Severe

Drug-Drug Interactions

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DomperidoneHalofantrine
Severe
How does the drug interact with Esonip-DSR Capsule:
Coadministration of Esonip-DSR Capsule with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Esonip-DSR Capsule and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Esonip-DSR Capsule:
Coadministration of Esonip-DSR Capsule with Nefazodone can increase the blood levels of Esonip-DSR Capsule.

How to manage the interaction:
There may be a possibility of interaction between Esonip-DSR Capsule and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Esonip-DSR Capsule:
Combining Mizolastine with Esonip-DSR Capsule can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Esonip-DSR Capsule and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Esonip-DSR Capsule:
Coadministration of Esonip-DSR Capsule with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Esonip-DSR Capsule and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Esonip-DSR Capsule:
Coadministration of Esonip-DSR Capsule with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Esonip-DSR Capsule and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Esonip-DSR Capsule:
Coadministration of Esonip-DSR Capsule with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Esonip-DSR Capsule and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with Esonip-DSR Capsule:
Coadministration of Esonip-DSR Capsule with Ritonavir can increase the blood levels of Esonip-DSR Capsule.

How to manage the interaction:
There may be a possibility of interaction between Esonip-DSR Capsule and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Esonip-DSR Capsule:
Coadministration of Esonip-DSR Capsule with Cisapride can increase the blood levels of Esonip-DSR Capsule.

How to manage the interaction:
There may be a possibility of interaction between Esonip-DSR Capsule and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Esonip-DSR Capsule:
Coadministration of Esonip-DSR Capsule with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Esonip-DSR Capsule and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Esonip-DSR Capsule:
Coadministration of Esonip-DSR Capsule with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Esonip-DSR Capsule and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 
  • Include more cool beverages in your food like clear soups, flavoured gelatin, and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
  • Drink after or any other liquid at least 30 minutes after eating food. After eating food, lie down for at least after 2 hours.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else cook food or use prepared food from the freezer.
  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Esonip-DSR Capsule Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Esonip-DSR Capsule contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

If you are intolerant to sugars, please inform your doctor before starting Esonip-DSR Capsule as it contains lactose. So, to avoid any unpleasant side effects, do as your doctor advises.

Yes, Esonip-DSR Capsule can cause dry mouth. In case you feel excessively thirsty, please increase your fluid intake and do frequent mouth rinses.

If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose.

Domperidone should be used for the shortest time. It is commonly taken for up to a week. Domperidone can produce irregular heartbeats if taken for an extended time or at a high dose.

No, it is a prescribed medication; it should be used only if specified by the doctor.

Drug-Drug Interactions Checker List

  • AMIODARONE
  • MOXIFLOXACIN
  • ERYTHROMYCIN
  • DILTIAZEM
  • SOTALOL
  • ESCITALOPRAM
  • VERAPAMIL

Disease/Condition Glossary

Nausea is a feeling of stomach uneasiness that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor in our brain known as the chemoreceptor zone (CTZ) controls vomiting.

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