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  3. Etoplast 100 mg Injection 5 ml

Etoplast 100 mg Injection 5 ml, Pack of 1 Injection
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

ETOPOSIDE-100MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Etoplast 100 mg Injection 5 ml

Etoplast 100 mg Injection 5 ml belongs to a class of chemotherapy drugs used to treat various cancer conditions, including testicular tumours or cancer of the testicles, lung cancer (small cell lung cancer; SCLC). Besides this, it can also be used in treating Monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4). Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

Etoplast 100 mg Injection 5 ml contains Etoposide, which is a podophyllotoxin derivative. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

Etoplast 100 mg Injection 5 ml will be administered by a qualified healthcare professional. Sometimes, Etoplast 100 mg Injection 5 ml may use certain side effects such as myelosuppression (bone marrow activity is decreased), leucopenia (reduction in the number of white cells in the blood), thrombocytopenia (deficiency of platelets), anaemia (deficiency of red cells), anorexia (lack or loss of appetite for food), fatigue (extreme tiredness), drowsiness, nausea, vomiting, alopecia, liver and kidney functional impairment, leukaemia, hypotension, haemorrhage, abdominal pain, diarrhoea, stomatitis (inflammation of the mucous membrane), hepatic dysfunction and increased bilirubin levels etc. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic or hypersensitive to any component present in the Etoplast 100 mg Injection 5 ml or if you are pregnant, plan to have a baby or are breastfeeding. You should not become pregnant or breastfeed while receiving an etoposide injection. If you become pregnant while on treatment with etoposide, call your doctor. Before taking the Etoplast 100 mg Injection 5 ml, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions. Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Etoplast 100 mg Injection 5 ml.

Uses of Etoplast 100 mg Injection 5 ml

Cancer [testicular cancer, small cell lung cancer, monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4)]

Directions for Use

Etoplast 100 mg Injection 5 ml will be administered by a qualified healthcare professional; do not self-administer.

Medicinal Benefits

Etoplast 100 mg Injection 5 ml is a chemotherapeutic medication that contains Etoposide. It is primarily used with other medications to treat testicular cancer that has not improved or worsened after treatment with other medications or radiation therapy. Etoposide injection is also used in conjunction with other drugs to treat a certain kind of lung cancer (small cell lung cancer; SCLC). It can also be used to treat monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4). Etoplast 100 mg Injection 5 ml acts by blocking an enzyme that promotes cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are halted or inhibited.

Storage

Store in a cool and dry place away from sunlight
Side effects of Etoplast 100 mg Injection 5 ml
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

Etoplast 100 mg Injection 5 ml is not recommended to use if you are allergic to etoposide, podophyllotoxines or podophyllotoxin-derivatives or any other ingredients of this medicine; If your liver is not working properly; If your bone marrow does not produce enough blood cells; If you are breast-feeding; If you have a weak immune system and you are being vaccinated against yellow fever at the same time. So, inform your doctor about your medical history and ongoing therapies. Etoposide can significantly reduce the number of blood cells in your bone marrow. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. A decrease in the number of blood cells in your body might produce symptoms and raise your chance of developing a serious infection or bleeding. If you notice any of the following symptoms, contact your doctor immediately.

Drug-Drug Interactions

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EtoposideRotavirus vaccine
Critical
EtoposideIdelalisib
Severe

Drug-Drug Interactions

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EtoposideRotavirus vaccine
Critical
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When the Rotavirus vaccine is used together with Etoplast 100 mg Injection 5 ml, it may not work as well.

How to manage the interaction:
Taking Etoplast 100 mg Injection 5 ml with the Rotavirus vaccine can cause an, please consult doctor before taking it. You may be at risk of acquiring an infection from the vaccination or having a decreased response of the vaccine depending on the dose and length of time you have been on Etoplast 100 mg Injection 5 ml. Do not discontinue any medications without a doctor's advice.
EtoposideIdelalisib
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Idelalisib, Idelalisib may increase the blood levels and effects of Etoplast 100 mg Injection 5 ml.

How to manage the interaction:
Taking Etoplast 100 mg Injection 5 ml with Idelalisib together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EtoposideIvacaftor
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Fenofibrate is used in combination with Ivacaftor, the blood levels of Fenofibrate might be raised.

How to manage the interaction:
Taking Etoplast 100 mg Injection 5 ml with Ivacaftor together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
EtoposideLeflunomide
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Leflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Leflunomide and Etoplast 100 mg Injection 5 ml, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideAdalimumab
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Adalimumab, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etoplast 100 mg Injection 5 ml and Adalimumab together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideInfliximab
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Infliximab is taken with Etoplast 100 mg Injection 5 ml, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Etoplast 100 mg Injection 5 ml with Infliximab can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
EtoposideFingolimod
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Fingolimod, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Etoplast 100 mg Injection 5 ml with Fingolimod together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideNatalizumab
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
Taking Etoplast 100 mg Injection 5 ml with natalizumab, especially taking both simultaneously with little to no time in between, may raise the risk of serious infections.

How to manage the interaction:
Although taking Etoplast 100 mg Injection 5 ml and Natalizumab together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. progressive weakening on one side of your body, clumsiness of limbs, visual disturbance, disorientation, or changes in your thinking, memory, or personality. Do not stop using any medications without talking to a doctor.
EtoposideVoclosporin
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Voclosporin, the risk of severe infections, as well as certain cancers including skin cancer and cancer of the lymph glands (lymphoma), increases.

How to manage the interaction:
Although taking Etoplast 100 mg Injection 5 ml and Voclosporin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, If you experience a fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not discontinue any medications without consulting a doctor.
EtoposideBaricitinib
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
Coadministration of baricitinib and Etoplast 100 mg Injection 5 ml can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Etoplast 100 mg Injection 5 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, and high fibre content. Also, eat small and frequent meals for a speedy recovery.
  • Avoid smoking and alcohol consumption. Also, avoid high fat and cholesterol diet.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Etoplast 100 mg Injection 5 ml Substitute

Substitutes safety advice

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:47 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Etoplast 100 mg Injection 5 ml contains Etoposide, which is used to treat various types of cancers. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

While taking Etoplast 100 mg Injection 5 ml, make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and urine tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Etoplast 100 mg Injection 5 ml.

Do not stop taking Etoplast 100 mg Injection 5 ml on your own. Take Etoplast 100 mg Injection 5 ml for as long as your doctor prescribes it, depending on your medical condition. Do not hesitate to speak with your doctor if you experience difficulty while taking Etoplast 100 mg Injection 5 ml.

Etoplast 100 mg Injection 5 ml can make you more likely to get infections or may worsen any current infections. Avoid contact with people with infections that may spread to others (such as chickenpox, measles, or flu). Consult your doctor if you have been exposed to an infection or for more details.

The live vaccine may not work while on treatment with Etoplast 100 mg Injection 5 ml. Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Etoposide can cause a significant decrease in the number of blood cells in your bone marrow. Your doctor will order laboratory testing on a regular basis before and during your therapy.

Drug-Drug Interactions Checker List

  • WARFARIN
  • CYCLOSPORINE
  • CISPLATIN
  • YELLOW FEVER VACCINE
  • PHENYTOIN
  • PHENYLBUTAZONE
  • SODIUM SALICYCLATE
  • ACETYLSALICYLIC ACID

Special Advise

  • A blood test is required to monitor liver function and blood cells while taking Etoplast 100 mg Injection 5 ml.
  • Do not have immunizations with live vaccines (for mumps, rubella, measles and BCG, yellow fever and shingles or pox chicken) while you’re having treatment and for up to 12 months afterwards.
  • Contact your doctor immediately if you experience any infection signs, including a temperature above 37.5 C or below 36 C.

Disease/Condition Glossary

Cancer: Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

Small-cell lung cancer: Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Leukaemia: Leukaemia is a type of blood cancer that affects blood cells in your bone marrow, usually white blood cells. Many types exist, such as monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4).

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