FESTONE COMBI KIT TABLET
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FESTONE COMBI KIT TABLET belongs to a group of gynaecological medications called ‘Abortifacient’ used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. FESTONE COMBI KIT TABLET also works in the second trimester of pregnancy.
FESTONE COMBI KIT TABLET contains two medicines, namely: Mifepristone and Misoprostol. Mifepristone is an anti-hormone (anti-progestogen) that blocks the effects of the progesterone hormone required in women to continue the pregnancy. On the other hand, Misoprostol is a prostaglandin that increases the womb’s (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. Thus, FESTONE COMBI KIT TABLET together cause termination of pregnancy and must be used one after the other for medical abortion.
A medical abortion generally involves 2-3 visits to a doctor or clinic, which includes giving medicines and then confirmation of termination of pregnancy. Following are the schedule involved in medical abortion:
In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of FESTONE COMBI KIT TABLET subside with time. But if vaginal bleeding does not stop, please visit the doctor immediately, as it requires immediate medical attention.
FESTONE COMBI KIT TABLET should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting FESTONE COMBI KIT TABLET if you have had an ectopic pregnancy (when the womb grows in the fallopian tube), using an intrauterine device, or you are breastfeeding, any bleeding disorder or heart problem. Do not strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.
FESTONE COMBI KIT TABLET contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone) needed to maintain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for FESTONE COMBI KIT TABLET to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete. On the other hand, the second medicine is Misoprostol, a prostaglandin analogue that helps increase uterine contractions and relaxes the cervix. Thus Together FESTONE COMBI KIT TABLET terminates the state of pregnancy. Misoprostol should be taken at least 24-36 hours after taking mifepristone, either orally or vaginally. This is a non-surgical method which is 90% successful.
Do not take FESTONE COMBI KIT TABLET if you are allergic to misoprostol and mifepristone, have a heart fitted with an artificial valve, have heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking FESTONE COMBI KIT TABLET in these conditions can cause life-threatening conditions in an individual. FESTONE COMBI KIT TABLET is known to cause sleepiness, so driving or operating machinery should not be done. If you use contraceptive devices like the intrauterine device (IUD), please remove it before taking FESTONE COMBI KIT TABLET. Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (a natural remedy used to treat mild depression) grapefruit juice should not be taken when taking FESTONE COMBI KIT TABLET as it is known to interact.
Drug-Drug Interactions: FESTONE COMBI KIT TABLET interacts with corticosteroids (dexamethasone), antifungal (ketoconazole, itraconazole), antibiotics (erythromycin, rifampicin), anti-epileptic (phenytoin, phenobarbital, carbamazepine), immunosuppressants (cyclosporine, tacrolimus, sirolimus), medicines to treat migraine (ergotamine). So, FESTONE COMBI KIT TABLET should not be taken along with these drugs.
Drug-Food Interactions: Please tell your doctor about all the Vitamins, herbs, and supplements you are taking as FESTONE COMBI KIT TABLET may interact with them to produce unpleasant side effects. Also, FESTONE COMBI KIT TABLET is known to interact with St John’s Wort (a natural remedy used to treat mild depression), and grapefruit juice.
Drug-Disease Interactions: FESTONE COMBI KIT TABLET should be taken with caution in people who have a bleeding problem, confirmed or suspected ectopic pregnancy, heart problem, liver or kidney disease, vaginal bleeding, porphyria (an inherited blood disease that may cause nervous system or skin problems).
Medical abortion: It is a procedure in which medicine is used to terminate a pregnancy. It is effectively causing abortion if performed in the first 70 days of pregnancy. Vagina bleeding occurs, and if it does not stop, please inform your doctor as it might require medical supervision. Having a medical abortion is a very emotional decision. You should be mentally prepared for all the risks a surgical absorption could lead to, like incomplete abortion, heavy and prolonged bleeding (may last up to 30 days), fever, digestive system discomfort fever. Also, if the medication does not work, it can lead to an unwanted ongoing pregnancy, leading to fetal defects. So, to avoid any complications, keep in regular touch with your doctor and do as advised.
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Alcohol
Unsafe
Alcohol is known to cause excessive drowsiness and increases uterine bleeding if taken along with FESTONE COMBI KIT TABLET.
Pregnancy
Unsafe
FESTONE COMBI KIT TABLET is used for medical abortion. If taken in pregnancy, it can lead to abortion.
Breast Feeding
Unsafe
FESTONE COMBI KIT TABLET should not be taken if breastfeeding as it may pass through the milk to the baby.
Driving
Unsafe
Driving is unsafe when taking FESTONE COMBI KIT TABLET as it might increase the risk of excessive bleeding.
Liver
Caution
FESTONE COMBI KIT TABLET to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
Caution
FESTONE COMBI KIT TABLET to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
Unsafe
FESTONE COMBI KIT TABLET is not recommended for children below the age of 12. The safety and effectiveness of FESTONE COMBI KIT TABLET have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give FESTONE COMBI KIT TABLET or not.
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