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Written By aquibnaseer ,
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Composition

GLIMEPIRIDE-4MG

Manufacturer/Marketer

Retra Life Science Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About GLIMICER 4MG TABLET 1

GLIMICER 4MG TABLET 1 belongs to a class of antidiabetic called 'sulfonylureas' used to lower raised blood sugar levels in Type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus - NIDDM). Type 2 diabetes develops if the body does not produce enough insulin or when your body's insulin does not work as well as it should. Insulin is a substance that helps to lower the level of sugar in your blood, especially after meals.

The GLIMICER 4MG TABLET 1 contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose. Therefore, it prevents symptoms of type 2 diabetes.

Take GLIMICER 4MG TABLET 1 as prescribed by your doctor. Some people may experience an allergic reaction (skin rash, hives & sensitivity to sun rays), liver dysfunction (jaundice, bile duct blockage, and hepatitis), seizures, coma & low glucose levels. Most of these side effects of GLIMICER 4MG TABLET 1 do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

GLIMICER 4MG TABLET 1 should not be stopped even if you feel better without consulting your doctor as the sugar level keeps changing. If you stop taking GLIMICER 4MG TABLET 1 abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). GLIMICER 4MG TABLET 1 should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease or plan to get pregnant or breastfeed.

Uses of GLIMICER 4MG TABLET 1

Type 2 diabetes

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

GLIMICER 4MG TABLET 1 is used in people with type 2 diabetes to minimize elevated blood sugar levels with a balanced diet and exercise in combination. GLIMICER 4MG TABLET 1 can be combined with insulin or other forms of oral antidiabetic medication. GLIMICER 4MG TABLET 1 decreases blood sugar levels in a diabetic patient by increasing the production and secretion of insulin from the pancreas beta cells. Thus, it helps in controlling increased blood sugar levels after the meal.

Storage

Store in a cool and dry place away from sunlight

Side Effects of GLIMICER 4MG TABLET 1

  • Allergic reactions
  • Headache
  • Nausea
  • Blood pressure drop
  • Shock
  • Abnormal liver function
  • Including skin and eye yellowing (jaundice)
  • Bile flow issues (cholestasis)
  • Liver inflammation (hepatitis) or failure of the liver

Drug Warnings

Before taking GLIMICER 4MG TABLET 1, inform your doctor if you are healing from injury, had or going to have surgery, have fever infections or other sources of stress, then contact your doctor as it might be appropriate to adjust care temporarily. If you have a serious kidney/liver disease, breastfeeding or pregnant, consult the doctor before using GLIMICER 4MG TABLET 1. Do not take GLIMICER 4MG TABLET 1 if you are allergic to sulpha drugs, glimepiride, or any other antidiabetic medicines or have a deficiency of glucose 6-phosphate dehydrogenase (G6PD). A heart disease patient should consult a doctor before taking the GLIMICER 4MG TABLET 1 as it may worsen the heart disease's current conditions. Do not take GLIMICER 4MG TABLET 1 with oral contraceptives as it may increase blood sugar levels. On the other hand, taking GLIMICER 4MG TABLET 1 with pain killers like aspirin or ibuprofen can lower your blood sugar.

Drug-Drug Interactions

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GlimepirideGrepafloxacin
Severe
GlimepirideOfloxacin
Severe

Drug-Drug Interactions

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GlimepirideGrepafloxacin
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Co-administration of Glimicer 4mg Tablet 10's with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Although there is a possible interaction between Glimicer 4mg Tablet 10's and Grepafloxacin, you can take these medicines together if prescribed by a doctor. If you experience any of these symptoms - low blood sugar, headache, dizziness, sleepiness, confusion, shaking, feeling hungry, weak, heart racing, high blood sugar, low blood sugar, serious infections, bleeding, feeling anxious, feeling sick or very thirsty - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
GlimepirideOfloxacin
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Co-administration of Ofloxacin and Glimicer 4mg Tablet 10's can sometimes have an effect on blood glucose levels.

How to manage the interaction:
Although combining Ofloxacin and Glimicer 4mg Tablet 10's can lead to an interaction, they can be taken on a doctor's advice. If you experience any symptoms of hypoglycemia (headache, dizziness, sleepiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweat, palpitation, and rapid heartbeat) or hyperglycemia (increased thirst, hunger, and urination), consult a doctor. Keep an eye on your blood glucose level. Do not discontinue any medications without consulting a doctor.
GlimepirideVoriconazole
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Co-administration of Glimicer 4mg Tablet 10's with Voriconazole may increase the blood levels and effects of Glimicer 4mg Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Glimicer 4mg Tablet 10's can be taken with voriconazole if prescribed by the doctor. Consult the prescriber if you experience headache, dizziness, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideMoxifloxacin
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Co-administration of Moxifloxacin can affect blood glucose levels. Both high blood glucose and low blood glucose.

How to manage the interaction:
Although there is a possible interaction, Glimicer 4mg Tablet 10's can be taken with Moxifloxacin if prescribed by the doctor. Consult the doctor if you experience headache, dizziness, rapid heartbeat, increased thirst, and increased urination. Do not discontinue the medications without consulting a doctor.
GlimepirideNorfloxacin
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Co-administration of Norfloxacin with Glimicer 4mg Tablet 10's may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Glimicer 4mg Tablet 10's can be taken with norfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
GlimepirideCiprofloxacin
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Taking ciprofloxacin with Glimicer 4mg Tablet 10's can cause both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
Although taking ciprofloxacin and Glimicer 4mg Tablet 10's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, excessive sweating, and rapid heartbeat or increased thirst, increased hunger, and increased urination. Do not discontinue the medications without consulting a doctor.
GlimepirideFluconazole
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Co-administration of Fluconazole may increase the blood levels and effects of Glimicer 4mg Tablet 10's may cause low blood glucose.

How to manage the interaction:
Although there is a possible interaction, Glimicer 4mg Tablet 10's can be taken with fluconazole if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideBumetanide
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Bumetanide may interfere with blood glucose control and reduce the effectiveness of Glimicer 4mg Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Glimicer 4mg Tablet 10's can be taken with bumetanide if prescribed by the doctor. Monitoring of blood glucose levels is advised.
GlimepirideLevofloxacin
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Co-administration of Glimicer 4mg Tablet 10's with Levofloxacin can affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Co-administration of Levofloxacin with Glimicer 4mg Tablet 10's can result in an interaction, it can be taken if a doctor has advised it. Consult the prescriber if you experience dizziness, drowsiness, headache, nervousness, confusion, tremors, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, increased urination, increased thirst, or increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideSunitinib
Severe
How does the drug interact with Glimicer 4mg Tablet 10's:
Taking Glimicer 4mg Tablet 10's with sunitinib may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Glimicer 4mg Tablet 10's can be taken with sunitinib if prescribed by the doctor. Consult the prescriber if you experience symptoms if low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.
  • Maintain healthy body weight as obesity is also related to the onset of diabetes.
  • Maintain a low fat and a low sugar diet. Replace carbohydrates containing foods with whole grains, fruits and vegetables as carbohydrates turn to sugars leading to high blood sugar.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS AND ANTIHYPERGLYCEMICS

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
GLIMEPIRIDE-4MGHypertensive heart and renal disease
Severe
GLIMEPIRIDE-4MGUnspecified kidney failure
Severe

Drug-Diseases Interactions

Login/Sign Up

GLIMEPIRIDE-4MGHypertensive heart and renal disease
Severe
How does the disease interact with Glimicer 4mg Tablet 10's:
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.

How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
GLIMEPIRIDE-4MGUnspecified kidney failure
Severe
How does the disease interact with Glimicer 4mg Tablet 10's:
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.

How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
GLIMEPIRIDE-4MGOther disorders of adrenal gland
Moderate
How does the disease interact with Glimicer 4mg Tablet 10's:
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.

How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
GLIMEPIRIDE-4MGAnaemia due to enzyme disorders
Moderate
How does the disease interact with Glimicer 4mg Tablet 10's:
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.

How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
GLIMEPIRIDE-4MGOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Glimicer 4mg Tablet 10's:
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.

How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.

FAQs

The GLIMICER 4MG TABLET 1 contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose. Therefore, it prevents symptoms of type 2 diabetes.

A patient is advised to take the missed dose as soon as possible or skip to the next dose if it's been too late. A patient should never attempt to take a double dose to compensate for the missed dose as it may prove harmful.

GLIMICER 4MG TABLET 1 is not recommended with warfarin as these two drugs are contraindicated with each other and hence may result in any harmful symptom when taken together in heart patients.

Avoid intake of GLIMICER 4MG TABLET 1 and consult a doctor if you have an allergy to sulfa drugs, diabetic ketoacidosis, heart disease, liver or kidney disease, an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).

Your blood sugar might get decreased, so regular blood glucose monitoring is required. Signs and symptoms of low blood sugar level are feeling very hungry, dizziness, irritability, confusion, anxiety or shakiness. Try to eat or drink a fast-acting sugar source (like fruit juice, hard candy, crackers, raisins or non-diet soda).

No, GLIMICER 4MG TABLET 1 is only prescribed to treat type 2 diabetes and not type 1 diabetes. If you are type 1 diabetic patient consult with a doctor so that insulin forms can be prescribed for the same.

The patient is advised to talk to a doctor before taking contraceptive pills if he/she is already taking GLIMICER 4MG TABLET 1, then the doctor may change the dose of GLIMICER 4MG TABLET 1. This is because oral contraceptive pills change body responds to the sugar.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • ROSUVASTATIN
  • DULOXETINE
  • DAPAGLIFLOZIN
  • GLYBURIDE
  • INSULIN
  • CANAGLIFLOZIN
  • SITAGLIPTIN
  • EMPAGLIFLOZIN
  • FUROSEMIDE
  • ATORVASTATIN
  • PREGABALIN
  • METFORMIN
  • NAPROXEN
  • CLOPIDOGREL
  • IBUPROFEN
  • WARFARIN

Disease/Condition Glossary

Type 2 diabetes: It is a chronic (long-lasting) condition that keeps the body from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also includes nerve problems, kidney problems, the damaged retina of eyes or blindness, loss of limbs, sexual dysfunction, and an increased chance of heart attack or stroke.

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