Hedfree Tablet 2's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Sunny S , MBBS

MRP ₹107.5

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₹16.1 Cashback (15%)

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Whats That

About Hedfree Tablet

Hedfree Tablet belongs to the class of medicines called 'antimigraine agents' used to prevent migraine symptoms such as headache, nausea, and vomiting. Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift. Hormonal changes, stress, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches.

Hedfree Tablet is a combination of two drugs, namely: Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain, thereby causing the narrowing of the brain's blood vessels, which in turn affects the blood flow patterns associated with headache. Naproxen is a painkiller which works by blocking the effect of chemical messengers that cause pain. Thus, Hedfree Tablet prevents symptoms of migraine-like headache, nausea and vomiting.

You are advised to take Hedfree Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeats, and heartburn. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Hedfree Tablet should not be taken during the third trimester of pregnancy. Hedfree Tablet may cause drowsiness and dizziness, so drive with caution. Hedfree Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Hedfree Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Hedfree Tablet

Migraine

Directions for Use

Take Hedfree Tablet with or without food. Swallow Hedfree Tablet as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Hedfree Tablet is a combination of two drugs, namely: Sumatriptan and Naproxen. Hedfree Tablet is indicated for the acute treatment of migraine with or without aura. Sumatriptan is a serotonin receptor agonist that acts on the serotonin (5-HT) receptors located in the brain, which causes the narrowing of the brain's blood vessels, thereby affecting the blood flow patterns with a headache. Naproxen is a pain killer which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the effect of COX enzymes, lesser prostaglandins are produced, thereby reducing pain in migraine.

Storage

Keep Hedfree Tablet out of reach and sight of children.

Side effects of Hedfree Tablet

Chest Pain

Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
Take rest and refrain from doing physical activity for a while, and restart after a few days.
Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Sudden Feeling Of Heat, Flushed Faced, And Sweat

Always wear loose-fitting clothes suitable for your activity during hot flashes.
Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
Drink plenty of water and stay hydrated.
Stay calm and lower your anxiety by practising yoga or meditation.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drowsiness

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Burning Or Tingling Sensation

Change positions or take a break from activity to relieve symptoms.
Avoid postures that put a lot of pressure on just one area of the body.
If you have vitamin deficiency, take supplements or change your diet.
Exercise regularly like cycling, walking or swimming.
Avoid sitting with your legs crossed.
Clench and unclench your fists and wiggle your toes.
Massage the affected area.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Drug Warnings

Do not take Hedfree Tablet if you are allergic to any of its contents; if you have had any recent heart surgery or stroke, blood circulation problems, heart problems, narrowing of blood vessels to the stomach, legs, arms or kidneys, or uncontrolled high blood pressure; if you are taking MAO inhibitors, antidepressant or have taken them in the last 14 days; or if you have taken 5-HT agonists called triptan or ergotamine in the last 24 hours. Inform your doctor if you have high blood pressure, asthma, diabetes, epilepsy, overweight, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Hedfree Tablet should not be taken during the third trimester of pregnancy. Hedfree Tablet may cause drowsiness and dizziness, so drive only if you are alert. Hedfree Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Hedfree Tablet as it could lead to increased drowsiness. Stop taking Hedfree Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.

Drug-Drug Interactions

NaproxenCidofovir

Critical

NaproxenKetorolac

Critical

Drug-Drug Interactions

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NaproxenCidofovir

Critical

How does the drug interact with Hedfree Tablet:
Taking cidofovir with Hedfree Tablet may increase the risk or severity of kidney problems

How to manage the interaction:
Taking Hedfree Tablet with Cidofovir is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.

NaproxenKetorolac

Critical

How does the drug interact with Hedfree Tablet:
Coadministration of Ketorolac with Hedfree Tablet can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac with Hedfree Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

NaproxenMeloxicam

Critical

How does the drug interact with Hedfree Tablet:
Co-administration of Hedfree Tablet with Meloxicam can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Hedfree Tablet is not advised as it can possibly result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness.

SumatriptanIsocarboxazid

Critical

How does the drug interact with Hedfree Tablet:
Combining Isocarboxazid with Hedfree Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related problems.

How to manage the interaction:
Taking Isocarboxazid with Hedfree Tablet is not recommended, please consult your doctor before taking it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.

SumatriptanBromocriptine

Critical

How does the drug interact with Hedfree Tablet:
Coadministration of Bromocriptine with Hedfree Tablet can increase the risk or severity of side effects like high blood pressure or heart-related disorders.

How to manage the interaction:
Although there is an interaction between Bromocriptine and Hedfree Tablet, they can be taken together if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, consult a doctor. Do not discontinue any medication without consulting a doctor.

SumatriptanErgotamine

Critical

How does the drug interact with Hedfree Tablet:
Coadministration of Ergotamine with Hedfree Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related disorders.

How to manage the interaction:
There may be a possibility of interaction between Hedfree Tablet and Ergotamine, but it can be taken if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.

SumatriptanMethylergometrine

Critical

How does the drug interact with Hedfree Tablet:
Coadministration of Hedfree Tablet with Methylergometrine can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Hedfree Tablet with Methylergometrine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

SumatriptanDihydroergotamine

Critical

How does the drug interact with Hedfree Tablet:
Coadministration of Dihydroergotamine with Hedfree Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related side effects.

How to manage the interaction:
Taking Dihydroergotamine with Hedfree Tablet is not recommended, please consult your doctor before taking it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.

NaproxenMipomersen

Severe

How does the drug interact with Hedfree Tablet:
Coadministration of Hedfree Tablet and Mipomersen may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Hedfree Tablet and Mipomersen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, confusion, diarrhea, vomiting, muscle weakness, muscle incoordination, tremor, blurred vision, ringing in the ear, excessive thirst, and/or increased urination, consult the doctor. Do not discontinue any medication without a doctor's advice.

NaproxenIopamidol

Severe

How does the drug interact with Hedfree Tablet:
Combine use of Hedfree Tablet and iopamidol may increase the effectiveness of iopamidol.

How to manage the interaction:
There may be a possible interaction between Hedfree Tablet and Iopamidol , but they can be taken together if they are prescribed by doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm and weakness consult the doctor. Do not discontinue any medication without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
Avoid bright lights, loud noise, and extreme temperatures.
Perform meditation and yoga. This helps in relieving stress and provides relaxation.
Follow a regular sleep pattern to improve the amount and quality of sleep you get.
Massage your scalp to ease the pain.
Lie down in a quiet, dark room.
Place a cold cloth over your forehead or neck.
Avoid smoking, alcohol, and caffeinated drinks.
Learn what triggers your migraine and try avoiding them.
Stay hydrated. Drink plenty of fluids.
Learn relaxation skills as they help in reducing stress.

Side Effects of Hedfree Tablet

Dizziness
Sleepiness
Nausea
Chest discomfort
Dry mouth
Irregular heartbeats
Heartburn

Habit Forming

No

Therapeutic Class

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:34 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Hedfree Tablet work?

Hedfree Tablet contains Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain; this causes the narrowing of the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Naproxen works by blocking the effect of chemical messengers that cause pain.

How to cope with dry mouth?

Dry mouth could be a side-effect of Hedfree Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

Is Hedfree Tablet used to prevent migraine attacks?

Hedfree Tablet treats a headache that has already begun but does not prevent or reduce the attacks. Hedfree Tablet should not be used to treat cluster headache or other types of headache, which may cause loss of movement on one side of the body.

Can I take pain killers along with Hedfree Tablet?

Hedfree Tablet contains Naproxen, an NSAID. Therefore, consult your doctor before taking any pain killer medicines, fever-reducing medicines, medicines for cold or sleeping problems along with Hedfree Tablet as they may also contain NSAID.

Can I take antihypertensives with Hedfree Tablet?

Talk to your doctor before taking Hedfree Tablet with anti-hypertensive medicines as they may cause impaired response when taken with painkiller. Regular monitoring of blood pressure levels is advised while taking Hedfree Tablet if you have high blood pressure. Hedfree Tablet should not be taken if you have uncontrolled high blood pressure.

I have stomach ulcers. Can I take Hedfree Tablet?

Hedfree Tablet contains painkiller, which might increase the risk of gastrointestinal adverse effects such as ulceration, bleeding, and perforation of intestines or stomach. Therefore, consult your doctor if you have stomach ulcers.

Drug-Drug Interactions Checker List

WARFARIN
ASPIRIN
LITHIUM
METHOTREXATE
DIGOXIN
CITALOPRAM
DULOXETINE
FLUOXETINE
DESVENLAFAXINE
METOPROLOL
OMEPRAZOLE

Disease/Condition Glossary

Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. Warning symptoms precede migraine headache one or two days before the headache itself. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability, and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, sensitivity to sound and light.