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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Napcet Tablet

Napcet Tablet belongs to the class of medicines called 'antimigraine agents' used to prevent migraine symptoms such as headache, nausea, and vomiting. Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift. Hormonal changes, stress, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. 

Napcet Tablet is a combination of two drugs, namely: Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain, thereby causing the narrowing of the brain's blood vessels, which in turn affects the blood flow patterns associated with headache. Naproxen is a painkiller which works by blocking the effect of chemical messengers that cause pain.  Thus, Napcet Tablet prevents symptoms of migraine-like headache, nausea and vomiting. 
 
You are advised to take Napcet Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeats, and heartburn. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently. 

Consult your doctor if you are pregnant or breastfeeding. Napcet Tablet should not be taken during the third trimester of pregnancy. Napcet Tablet may cause drowsiness and dizziness, so drive with caution. Napcet Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Napcet Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects. 

Uses of Napcet Tablet

Migraine 

Directions for Use

Take Napcet Tablet with or without food. Swallow Napcet Tablet as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Napcet Tablet is a combination of two drugs, namely: Sumatriptan and Naproxen. Napcet Tablet is indicated for the acute treatment of migraine with or without aura. Sumatriptan is a serotonin receptor agonist that acts on the serotonin (5-HT) receptors located in the brain, which causes the narrowing of the brain's blood vessels, thereby affecting the blood flow patterns with a headache. Naproxen is a pain killer which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the effect of COX enzymes, lesser prostaglandins are produced, thereby reducing pain in migraine. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Napcet Tablet

  • Dizziness
  • Sleepiness
  • Nausea
  • Chest discomfort
  • Dry mouth
  • Irregular heartbeats
  • Heartburn

Drug Warnings

Do not take Napcet Tablet if you are allergic to any of its contents; if you have had any recent heart surgery or stroke, blood circulation problems, heart problems, narrowing of blood vessels to the stomach, legs, arms or kidneys, or uncontrolled high blood pressure; if you are taking MAO inhibitors, antidepressant or have taken them in the last 14 days; or if you have taken 5-HT agonists called triptan or ergotamine in the last 24 hours. Inform your doctor if you have high blood pressure, asthma, diabetes, epilepsy, overweight, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Napcet Tablet should not be taken during the third trimester of pregnancy. Napcet Tablet may cause drowsiness and dizziness, so drive only if you are alert. Napcet Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Napcet Tablet as it could lead to increased drowsiness. Stop taking Napcet Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. 

Drug-Drug Interactions

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NaproxenMeloxicam
Critical
NaproxenCidofovir
Critical

Drug-Drug Interactions

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NaproxenMeloxicam
Critical
How does the drug interact with Napcet Tablet:
Co-administration of Napcet Tablet with Meloxicam can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Napcet Tablet is not advised as it can possibly result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness.
NaproxenCidofovir
Critical
How does the drug interact with Napcet Tablet:
Taking cidofovir with Napcet Tablet may increase the risk or severity of kidney problems

How to manage the interaction:
Taking Napcet Tablet with Cidofovir is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
NaproxenKetorolac
Critical
How does the drug interact with Napcet Tablet:
Coadministration of Ketorolac with Napcet Tablet can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac with Napcet Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
SumatriptanDihydroergotamine
Critical
How does the drug interact with Napcet Tablet:
Coadministration of Dihydroergotamine with Napcet Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related side effects.

How to manage the interaction:
Taking Dihydroergotamine with Napcet Tablet is not recommended, please consult your doctor before taking it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
SumatriptanMethylergometrine
Critical
How does the drug interact with Napcet Tablet:
Coadministration of Napcet Tablet with Methylergometrine can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Napcet Tablet with Methylergometrine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SumatriptanErgotamine
Critical
How does the drug interact with Napcet Tablet:
Coadministration of Ergotamine with Napcet Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related disorders.

How to manage the interaction:
There may be a possibility of interaction between Napcet Tablet and Ergotamine, but it can be taken if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
SumatriptanBromocriptine
Critical
How does the drug interact with Napcet Tablet:
Coadministration of Bromocriptine with Napcet Tablet can increase the risk or severity of side effects like high blood pressure or heart-related disorders.

How to manage the interaction:
Although there is an interaction between Bromocriptine and Napcet Tablet, they can be taken together if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, consult a doctor. Do not discontinue any medication without consulting a doctor.
SumatriptanIsocarboxazid
Critical
How does the drug interact with Napcet Tablet:
Combining Isocarboxazid with Napcet Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related problems.

How to manage the interaction:
Taking Isocarboxazid with Napcet Tablet is not recommended, please consult your doctor before taking it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
NaproxenIodamide
Severe
How does the drug interact with Napcet Tablet:
Coadministration of Napcet Tablet and iodamide may increase the effectiveness of iodamide.

How to manage the interaction:
There may be a possible interaction between Napcet Tablet and Iodamide, but they can be taken together if they are prescribed by doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm and weakness consult the doctor. Do not discontinue any medication without a doctor's advice.
NaproxenFlurbiprofen
Severe
How does the drug interact with Napcet Tablet:
Coadministration of Napcet Tablet with flurbiprofen can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Napcet Tablet with flurbiprofen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Avoid bright lights, loud noise, and extreme temperatures.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Massage your scalp to ease the pain.
  • Lie down in a quiet, dark room.
  • Place a cold cloth over your forehead or neck.
  • Avoid smoking, alcohol, and caffeinated drinks. 
  • Learn what triggers your migraine and try avoiding them.
  • Stay hydrated. Drink plenty of fluids.
  • Learn relaxation skills as they help in reducing stress.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

Napcet Tablet Substitute

Substitutes safety advice
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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Napcet Tablet contains Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain; this causes the narrowing of the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Naproxen works by blocking the effect of chemical messengers that cause pain.

Dry mouth could be a side-effect of Napcet Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

Napcet Tablet treats a headache that has already begun but does not prevent or reduce the attacks. Napcet Tablet should not be used to treat cluster headache or other types of headache, which may cause loss of movement on one side of the body.

Napcet Tablet contains Naproxen, an NSAID. Therefore, consult your doctor before taking any pain killer medicines, fever-reducing medicines, medicines for cold or sleeping problems along with Napcet Tablet as they may also contain NSAID.

Talk to your doctor before taking Napcet Tablet with anti-hypertensive medicines as they may cause impaired response when taken with painkiller. Regular monitoring of blood pressure levels is advised while taking Napcet Tablet if you have high blood pressure. Napcet Tablet should not be taken if you have uncontrolled high blood pressure.

Napcet Tablet contains painkiller, which might increase the risk of gastrointestinal adverse effects such as ulceration, bleeding, and perforation of intestines or stomach. Therefore, consult your doctor if you have stomach ulcers.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • LITHIUM
  • METHOTREXATE
  • DIGOXIN
  • CITALOPRAM
  • DULOXETINE
  • FLUOXETINE
  • DESVENLAFAXINE
  • METOPROLOL
  • OMEPRAZOLE

Disease/Condition Glossary

Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. Warning symptoms precede migraine headache one or two days before the headache itself. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability, and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, sensitivity to sound and light. 

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