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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Megma Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Niprameg-S Tablet 4's

Niprameg-S Tablet 4's belongs to the class of medicines called 'antimigraine agents' used to prevent migraine symptoms such as headache, nausea, and vomiting. Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift. Hormonal changes, stress, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. 

Niprameg-S Tablet 4's is a combination of two drugs, namely: Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain, thereby causing the narrowing of the brain's blood vessels, which in turn affects the blood flow patterns associated with headache. Naproxen is a painkiller which works by blocking the effect of chemical messengers that cause pain.  Thus, Niprameg-S Tablet 4's prevents symptoms of migraine-like headache, nausea and vomiting. 
 
You are advised to take Niprameg-S Tablet 4's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeats, and heartburn. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently. 

Consult your doctor if you are pregnant or breastfeeding. Niprameg-S Tablet 4's should not be taken during the third trimester of pregnancy. Niprameg-S Tablet 4's may cause drowsiness and dizziness, so drive with caution. Niprameg-S Tablet 4's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Niprameg-S Tablet 4's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects. 

Uses of Niprameg-S Tablet 4's

Migraine 

Directions for Use

Take Niprameg-S Tablet 4's with or without food. Swallow Niprameg-S Tablet 4's as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Niprameg-S Tablet 4's is a combination of two drugs, namely: Sumatriptan and Naproxen. Niprameg-S Tablet 4's is indicated for the acute treatment of migraine with or without aura. Sumatriptan is a serotonin receptor agonist that acts on the serotonin (5-HT) receptors located in the brain, which causes the narrowing of the brain's blood vessels, thereby affecting the blood flow patterns with a headache. Naproxen is a pain killer which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the effect of COX enzymes, lesser prostaglandins are produced, thereby reducing pain in migraine. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Niprameg-S Tablet 4's if you are allergic to any of its contents; if you have had any recent heart surgery or stroke, blood circulation problems, heart problems, narrowing of blood vessels to the stomach, legs, arms or kidneys, or uncontrolled high blood pressure; if you are taking MAO inhibitors, antidepressant or have taken them in the last 14 days; or if you have taken 5-HT agonists called triptan or ergotamine in the last 24 hours. Inform your doctor if you have high blood pressure, asthma, diabetes, epilepsy, overweight, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Niprameg-S Tablet 4's should not be taken during the third trimester of pregnancy. Niprameg-S Tablet 4's may cause drowsiness and dizziness, so drive only if you are alert. Niprameg-S Tablet 4's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Niprameg-S Tablet 4's as it could lead to increased drowsiness. Stop taking Niprameg-S Tablet 4's and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Niprameg-S Tablet:
Co-administration of Niprameg-S Tablet with Meloxicam can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Niprameg-S Tablet is not advised as it can possibly result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness.
How does the drug interact with Niprameg-S Tablet:
Coadministration of Ketorolac with Niprameg-S Tablet can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac with Niprameg-S Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Niprameg-S Tablet:
Taking cidofovir with Niprameg-S Tablet may increase the risk or severity of kidney problems

How to manage the interaction:
Taking Niprameg-S Tablet with Cidofovir is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
SumatriptanDihydroergotamine
Critical
How does the drug interact with Niprameg-S Tablet:
Coadministration of Dihydroergotamine with Niprameg-S Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related side effects.

How to manage the interaction:
Taking Dihydroergotamine with Niprameg-S Tablet is not recommended, please consult your doctor before taking it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
SumatriptanErgotamine
Critical
How does the drug interact with Niprameg-S Tablet:
Coadministration of Ergotamine with Niprameg-S Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related disorders.

How to manage the interaction:
There may be a possibility of interaction between Niprameg-S Tablet and Ergotamine, but it can be taken if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Niprameg-S Tablet:
Coadministration of Bromocriptine with Niprameg-S Tablet can increase the risk or severity of side effects like high blood pressure or heart-related disorders.

How to manage the interaction:
Although there is an interaction between Bromocriptine and Niprameg-S Tablet, they can be taken together if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Niprameg-S Tablet:
Coadministration of Niprameg-S Tablet with Methylergometrine can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Niprameg-S Tablet with Methylergometrine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SumatriptanIsocarboxazid
Critical
How does the drug interact with Niprameg-S Tablet:
Combining Isocarboxazid with Niprameg-S Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related problems.

How to manage the interaction:
Taking Isocarboxazid with Niprameg-S Tablet is not recommended, please consult your doctor before taking it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Niprameg-S Tablet:
Coadministration of Niprameg-S Tablet and Everolimus can increase the risk or severity of kidney problems

How to manage the interaction:
Taking Niprameg-S Tablet and Everolimus together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medication without a doctor's advice.
How does the drug interact with Niprameg-S Tablet:
Using deferasirox together with Niprameg-S Tablet may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Niprameg-S Tablet with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Avoid bright lights, loud noise, and extreme temperatures.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Massage your scalp to ease the pain.
  • Lie down in a quiet, dark room.
  • Place a cold cloth over your forehead or neck.
  • Avoid smoking, alcohol, and caffeinated drinks. 
  • Learn what triggers your migraine and try avoiding them.
  • Stay hydrated. Drink plenty of fluids.
  • Learn relaxation skills as they help in reducing stress.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Niprameg-S Tablet 4's contains Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain; this causes the narrowing of the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Naproxen works by blocking the effect of chemical messengers that cause pain.

Dry mouth could be a side-effect of Niprameg-S Tablet 4's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

Niprameg-S Tablet 4's treats a headache that has already begun but does not prevent or reduce the attacks. Niprameg-S Tablet 4's should not be used to treat cluster headache or other types of headache, which may cause loss of movement on one side of the body.

Niprameg-S Tablet 4's contains Naproxen, an NSAID. Therefore, consult your doctor before taking any pain killer medicines, fever-reducing medicines, medicines for cold or sleeping problems along with Niprameg-S Tablet 4's as they may also contain NSAID.

Talk to your doctor before taking Niprameg-S Tablet 4's with anti-hypertensive medicines as they may cause impaired response when taken with painkiller. Regular monitoring of blood pressure levels is advised while taking Niprameg-S Tablet 4's if you have high blood pressure. Niprameg-S Tablet 4's should not be taken if you have uncontrolled high blood pressure.

Niprameg-S Tablet 4's contains painkiller, which might increase the risk of gastrointestinal adverse effects such as ulceration, bleeding, and perforation of intestines or stomach. Therefore, consult your doctor if you have stomach ulcers.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • LITHIUM
  • METHOTREXATE
  • DIGOXIN
  • CITALOPRAM
  • DULOXETINE
  • FLUOXETINE
  • DESVENLAFAXINE
  • METOPROLOL
  • OMEPRAZOLE

Disease/Condition Glossary

Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. Warning symptoms precede migraine headache one or two days before the headache itself. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability, and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, sensitivity to sound and light. 

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