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  3. Hepakal 5000 IU Injection

Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

HEPARIN-5000IU

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Hepakal 5000 IU Injection

Hepakal 5000 IU Injection belongs to a class of drugs called anticoagulants or blood thinners. Hepakal 5000 IU Injection is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Hepakal 5000 IU Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

Hepakal 5000 IU Injection will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Hepakal 5000 IU Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Hepakal 5000 IU Injection or any other medicines, please tell your doctor. It is not known whether Hepakal 5000 IU Injection harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Hepakal 5000 IU Injection. Hepakal 5000 IU Injection is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Hepakal 5000 IU Injection.

Uses of Hepakal 5000 IU Injection

Prevention of blood clots.

Directions for Use

Hepakal 5000 IU Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Hepakal 5000 IU Injection is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Hepakal 5000 IU Injection also reduces the risk of blood clots during surgeries (like heart surgery). Hepakal 5000 IU Injection is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Storage

Keep Hepakal 5000 IU Injection out of the sight and reach of children.

Drug Warnings

Use Hepakal 5000 IU Injection cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Hepakal 5000 IU Injection. Patients should inform the doctor that they are receiving Hepakal 5000 IU Injection before any surgery is scheduled.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Hepakal 5000 IU Injection:
Taking Tenecteplase with Hepakal 5000 IU Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Hepakal 5000 IU Injection with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepakal 5000 IU Injection:
Taking Ticlopidine with Hepakal 5000 IU Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Hepakal 5000 IU Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Hepakal 5000 IU Injection:
When Hepakal 5000 IU Injection is taken with bazedoxifene the effects of Hepakal 5000 IU Injection are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Hepakal 5000 IU Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepakal 5000 IU Injection:
Taking Alteplase with Hepakal 5000 IU Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Hepakal 5000 IU Injection with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepakal 5000 IU Injection:
Taking Mifepristone with Hepakal 5000 IU Injection can increase the risk of negative side effects.

How to manage the interaction:
Taking Hepakal 5000 IU Injection with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Hepakal 5000 IU Injection:
Using Hepakal 5000 IU Injection with Oritavancin can make Hepakal 5000 IU Injection less effective as a therapy.

How to manage the interaction:
Hepakal 5000 IU Injection is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Hepakal 5000 IU Injection's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepakal 5000 IU Injection:
Taking Bivalirudin with Hepakal 5000 IU Injection may increase the risk of bleeding.

How to manage the interaction:
Although taking Bivalirudin and Hepakal 5000 IU Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hepakal 5000 IU Injection:
Co-administration of Ibrutinib with Hepakal 5000 IU Injection can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ibrutinib and Hepakal 5000 IU Injection, but it can be taken if prescribed by a doctor. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hepakal 5000 IU Injection:
Taking fondaparinux with Hepakal 5000 IU Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Fondaparinux with Hepakal 5000 IU Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hepakal 5000 IU Injection:
Taking Hepakal 5000 IU Injection with Deferasirox can increase the risk of gastrointestinal bleeding and ulcer.

How to manage the interaction:
Taking Deferasirox with Hepakal 5000 IU Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor, if you experience stomach pain, bloating, dizziness, lightheadedness, loss of hunger, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Hepakal 5000 IU Injection along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Hepakal 5000 IU Injection.

Side Effects of Hepakal 5000 IU Injection

  • Red itchy patches or lumps at the site of injection
  • Unusual bleeding
  • Skin redness

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to take ibuprofen with Hepakal 5000 IU Injection as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Hepakal 5000 IU Injection.

Yes, Hepakal 5000 IU Injection may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Hepakal 5000 IU Injection may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Hepakal 5000 IU Injection may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Hepakal 5000 IU Injection to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Special Advise

Regular blood tests are advised while taking Hepakal 5000 IU Injection to monitor prothrombin, platelets and coagulation time on regular basis.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

Have a query?

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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Hepakal 5000 IU Injection as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Hepakal 5000 IU Injection is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Hepakal 5000 IU Injection should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Hepakal 5000 IU Injection usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Hepakal 5000 IU Injection should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Hepakal 5000 IU Injection should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Hepakal 5000 IU Injection is not recommended for children below 2 months.

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