Hepagrit-25000 Injection 5 ml belongs to a class of drugs called anticoagulants or blood thinners. Hepagrit-25000 Injection 5 ml is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Hepagrit-25000 Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

Hepagrit-25000 Injection 5 ml will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Hepagrit-25000 Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Hepagrit-25000 Injection 5 ml or any other medicines, please tell your doctor. It is not known whether Hepagrit-25000 Injection 5 ml harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Hepagrit-25000 Injection 5 ml. Hepagrit-25000 Injection 5 ml is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Hepagrit-25000 Injection 5 ml.

Hepagrit-25000 Injection 5 ml is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Hepagrit-25000 Injection 5 ml also reduces the risk of blood clots during surgeries (like heart surgery). Hepagrit-25000 Injection 5 ml is used as an anticoagulant in blood transfusion and in a dialysis procedure.

• Red itchy patches or lumps at the site of injection
• Unusual bleeding
• Skin redness

Use Hepagrit-25000 Injection 5 ml cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Hepagrit-25000 Injection 5 ml. Patients should inform the doctor that they are receiving Hepagrit-25000 Injection 5 ml before any surgery is scheduled.

Drug-Drug Interaction: Hepagrit-25000 Injection 5 ml may have interaction with pain killers (salicylic acid, ibuprofen, indomethacin, phenylbutazone, and celecoxib), dextran, anti-malarial (hydroxychloroquine), blood thinner (abciximab, eptifibatide, dipyridamole), heart medicines (digitalis), antibiotic (tetracycline), nicotine, antiallergics, or blood pressure-lowering pills (nitroglycerin)

Drug-Food Interaction: Hepagrit-25000 Injection 5 ml may interact with alcohol. Avoid foods rich in vitamin K like coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, brussels sprouts as they may affect the working of Hepagrit-25000 Injection 5 ml. It is advisable to avoid smoking and use of tobacco products and nicotine as they may reduce the effectiveness of Hepagrit-25000 Injection 5 ml.

Drug-Disease Interaction: Use with caution in patients with bleeding problems, low platelet count (thrombocytopenia) and thrombosis (blood clot in veins).

• SALICYLIC ACID
• IBUPROFEN
• INDOMETHACIN
• PHENYLBUTAZONE
• CELECOXIB
• HYDROXYCHLOROQUINE
• ABCIXIMAB
• DIPYRIDAMOLE
• DIGITALIS
• TETRACYCLINE
• NITROGLYCERIN

Regular blood tests are advised while taking Hepagrit-25000 Injection 5 ml to monitor prothrombin, platelets and coagulation time on regular basis.

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.