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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Last Updated Aug 20, 2024 | 12:51 PM IST

About Lefumov-10 Tablet 10's

Lefumov-10 Tablet 10's belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales). 

Lefumov-10 Tablet 10's contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling. 

Take Lefumov-10 Tablet 10's at the same time every day as prescribed by your doctor. In some cases, Lefumov-10 Tablet 10's may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Lefumov-10 Tablet 10's if you are pregnant or planning for pregnancy as Lefumov-10 Tablet 10's may cause serious congenital disabilities. Lefumov-10 Tablet 10's should not be taken by breastfeeding mothers as it passes into breast milk. Lefumov-10 Tablet 10's may cause dizziness, so drive with caution. Avoid consuming alcohol along with Lefumov-10 Tablet 10's as it could lead to increased dizziness and liver damage. Lefumov-10 Tablet 10's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Uses of Lefumov-10 Tablet 10's

Rheumatoid arthritis, Psoriatic arthritis

Medicinal Benefits

Lefumov-10 Tablet 10's belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Lefumov-10 Tablet 10's is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.

Directions for Use

Take Lefumov-10 Tablet 10's with or without food. Swallow Lefumov-10 Tablet 10's as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lefumov-10 Tablet 10's

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Indigestion
  • Rash
  • Hair loss

Drug Warnings

Do not take Lefumov-10 Tablet 10's if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Lefumov-10 Tablet 10's is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Lefumov-10 Tablet 10's if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Lefumov-10 Tablet 10's may cause dizziness, so drive with caution. Lefumov-10 Tablet 10's may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Drug Interactions

Drug-Drug Interactions: Lefumov-10 Tablet 10's may interact with pain killers (ibuprofen, naproxen, acetaminophen, aspirin), anti-depressant (duloxetine), corticosteroids (prednisone), drugs used to treat arthritis (celecoxib, azathioprine, etanercept, adalimumab, meloxicam, methotrexate, abatacept, infliximab), and anti-malarial (hydroxychloroquine). 

Drug-Food Interactions: Avoid consuming alcohol along with Lefumov-10 Tablet 10's as it could lead to liver damage.

Drug-Disease Interactions: Inform your doctor if you have low immunity, pneumonia, tuberculosis (TB), hypertension (high blood pressure), lung toxicity, peripheral neuropathy (nerve damage), liver and kidney dysfunction.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ACETAMINOPHEN
  • ASPIRIN
  • DULOXETINE
  • PREDNISONE
  • CELECOXIB
  • AZATHIOPRINE
  • MELOXICAM
  • METHOTREXATE
  • ETANERCEPT
  • ADALIMUMAB
  • ABATACEPT
  • INFLIXIMAB
  • HYDROXYCHLOROQUINE

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Special Advise

Regular blood tests to monitor your liver function after starting Lefumov-10 Tablet 10's, and for every 6-8 weeks are advised.

Disease/Condition Glossary

Rheumatoid arthritis: It is an auto-immune disease (where the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty in moving and swelling. Patients with rheumatoid arthritis have intense joint pain (especially knee joint) with stiffness. 

Psoriatic arthritis: Psoriatic arthritis is an autoimmune disease characterized by inflammation of the skin (psoriasis) and joints (inflammatory arthritis). It mainly affects large joints in the lower extremities, distal joints of toes and fingers, back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.

About Lefumov-10 Tablet 10's

Lefumov-10 Tablet 10's belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales). 

Lefumov-10 Tablet 10's contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling. 

Take Lefumov-10 Tablet 10's at the same time every day as prescribed by your doctor. In some cases, Lefumov-10 Tablet 10's may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Lefumov-10 Tablet 10's if you are pregnant or planning for pregnancy as Lefumov-10 Tablet 10's may cause serious congenital disabilities. Lefumov-10 Tablet 10's should not be taken by breastfeeding mothers as it passes into breast milk. Lefumov-10 Tablet 10's may cause dizziness, so drive with caution. Avoid consuming alcohol along with Lefumov-10 Tablet 10's as it could lead to increased dizziness and liver damage. Lefumov-10 Tablet 10's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Non returnable*
COD available

Online payment accepted

Prescription drug

Whats That

tooltip
Non returnable*
COD available

Online payment accepted

Composition

LEFLUNOMIDE-10MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Lefumov-10 Tablet 10's

Rheumatoid arthritis, Psoriatic arthritis

Medicinal Benefits

Lefumov-10 Tablet 10's belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Lefumov-10 Tablet 10's is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.

Side Effects of Lefumov-10 Tablet 10's

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Indigestion
  • Rash
  • Hair loss

Directions for Use

Take Lefumov-10 Tablet 10's with or without food. Swallow Lefumov-10 Tablet 10's as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Lefumov-10 Tablet 10's if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Lefumov-10 Tablet 10's is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Lefumov-10 Tablet 10's if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Lefumov-10 Tablet 10's may cause dizziness, so drive with caution. Lefumov-10 Tablet 10's may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Therapeutic Class

ANTIRHEUMATICS

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ACETAMINOPHEN
  • ASPIRIN
  • DULOXETINE
  • PREDNISONE
  • CELECOXIB
  • AZATHIOPRINE
  • MELOXICAM
  • METHOTREXATE
  • ETANERCEPT
  • ADALIMUMAB
  • ABATACEPT
  • INFLIXIMAB
  • HYDROXYCHLOROQUINE

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Special Advise

Regular blood tests to monitor your liver function after starting Lefumov-10 Tablet 10's, and for every 6-8 weeks are advised.

Disease/Condition Glossary

Rheumatoid arthritis: It is an auto-immune disease (where the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty in moving and swelling. Patients with rheumatoid arthritis have intense joint pain (especially knee joint) with stiffness. 

Psoriatic arthritis: Psoriatic arthritis is an autoimmune disease characterized by inflammation of the skin (psoriasis) and joints (inflammatory arthritis). It mainly affects large joints in the lower extremities, distal joints of toes and fingers, back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.

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