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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Dr Reddy'S Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Lenangio 25 mg Capsule 10's

Lenangio 25 mg Capsule 10's belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenangio 25 mg Capsule 10's is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS where part of chromosome 5 is missing.
 
Lenangio 25 mg Capsule 10's contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenangio 25 mg Capsule 10's kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Lenangio 25 mg Capsule 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Lenangio 25 mg Capsule 10's if you are pregnant or breastfeeding. Lenangio 25 mg Capsule 10's may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Lenangio 25 mg Capsule 10's is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Lenangio 25 mg Capsule 10's must use effective contraception. Inform your doctor regarding your health condition and medications before taking Lenangio 25 mg Capsule 10's to rule out any interactions.

Uses of Lenangio 25 mg Capsule 10's

Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Lenangio 25 mg Capsule 10's as a whole with water; do not crush or chew it.

Medicinal Benefits

Lenangio 25 mg Capsule 10's belongs to the group of medicines called immunomodulatory agents. Lenangio 25 mg Capsule 10's is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenangio 25 mg Capsule 10's works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenangio 25 mg Capsule 10's kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Lenangio 25 mg Capsule 10's is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lenangio 25 mg Capsule 10's

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

Drug Warnings

Do not take Lenangio 25 mg Capsule 10's if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Lenangio 25 mg Capsule 10's if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Lenangio 25 mg Capsule 10's if you are breastfeeding as it is not unknown if it passes into breastmilk. Lenangio 25 mg Capsule 10's may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Lenangio 25 mg Capsule 10's is not recommended for use in children. Avoid consuming alcohol along with Lenangio 25 mg Capsule 10's as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
LenalidomideRotavirus vaccine
Critical

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
How does the drug interact with Lenangio 25 mg Capsule:
Taking anakinra with Lenangio 25 mg Capsule can increase the risk of negative side effects.

How to manage the interaction:
Taking Lenangio 25 mg Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideRotavirus vaccine
Critical
How does the drug interact with Lenangio 25 mg Capsule:
Administering the Rotavirus vaccine together with Lenangio 25 mg Capsule may increase the risk of infections.

How to manage the interaction:
Taking Lenangio 25 mg Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Lenangio 25 mg Capsule. Do not stop using any medications without consulting a doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Lenangio 25 mg Capsule:
When combining the Yellow fever vaccine with Lenangio 25 mg Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenangio 25 mg Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Lenangio 25 mg Capsule:
Combining the BCG vaccine with Lenangio 25 mg Capsule increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenangio 25 mg Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideCladribine
Severe
How does the drug interact with Lenangio 25 mg Capsule:
Taking cladribine with Lenangio 25 mg Capsule can increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction between Lenangio 25 mg Capsule and cladribine, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor. Do not discontinue any medications without consulting a doctor.
LenalidomideAtezolizumab
Severe
How does the drug interact with Lenangio 25 mg Capsule:
Using Atezolizumab and Lenangio 25 mg Capsule can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Atezolizumab and Lenangio 25 mg Capsule, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomidePalifermin
Severe
How does the drug interact with Lenangio 25 mg Capsule:
When Palifermin is used with Lenangio 25 mg Capsule, it might reduce its effectiveness and potentially exacerbate mouth ulcers.

How to manage the interaction:
Although there is a possible interaction between Lenangio 25 mg Capsule and Palifermin, you can take these medicines together if prescribed by your doctor. If you have painful sores or ulcers in your mouth, it's important to contact your doctor right away. It is recommended not to use palifermin within 24 hours before or after treatment with Lenangio 25 mg Capsule. Do not discontinue any medications without consulting your doctor.
LenalidomideAtorvastatin
Severe
How does the drug interact with Lenangio 25 mg Capsule:
Coadministration of atorvastatin with Lenangio 25 mg Capsule can increase the risk of rhabdomyolysis (a rare condition that results in skeletal muscle tissue damage).

How to manage the interaction:
Although there is an interaction between atorvastatin and Lenangio 25 mg Capsule, it can be taken if a doctor has advised it. However, if you experience unexplained muscle pain, tenderness, or weakness accompanied by fever, dark-coloured urine, or light-coloured stools, consult a doctor immediately. breath. Do not discontinue any medications without consulting a doctor.
LenalidomideDeferiprone
Severe
How does the drug interact with Lenangio 25 mg Capsule:
Taking Lenangio 25 mg Capsule with deferiprone together can cause a decrease in white blood cell count.

How to manage the interaction:
Although there is an interaction between Lenangio 25 mg Capsule and deferiprone, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideFilgrastim
Severe
How does the drug interact with Lenangio 25 mg Capsule:
Using filgrastim together with Lenangio 25 mg Capsule can reduce the effect of filgrastim.

How to manage the interaction:
Co-administration of Filgrastim with Lenangio 25 mg Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.
  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Lenangio 25 mg Capsule 10's Substitute

Substitutes safety advice
  • Lenalid 25 mg Capsule 30's

    by Others

    239.30per tablet
  • Lenasted 25 Capsule 10's

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    26.27per tablet
  • Laviat 25 mg Capsule 10's

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • ERYTHROPOIETIN

Special Advise

  • Do not take Lenangio 25 mg Capsule 10's if you are pregnant as it might cause severe birth defects or death of the unborn baby.
  • Male patients taking Lenangio 25 mg Capsule 10's must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.
  • You must not donate blood while taking Lenangio 25 mg Capsule 10's and for 4weeks after discontinuing Lenangio 25 mg Capsule 10's.
  • Lenangio 25 mg Capsule 10's might increase the risk of blood clots. Inform your doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of the arm or leg.
  • Lenangio 25 mg Capsule 10's might cause abnormal/increase in liver test results, inform the person doing the test that you are taking Lenangio 25 mg Capsule 10's.
  • Lenangio 25 mg Capsule 10's might increase/decrease your blood sugar levels. Regularly monitor blood glucose levels while taking Lenangio 25 mg Capsule 10's. Consult your doctor if you are diabetic.
  • Inform your doctor if you have any kidney dysfunction as Lenangio 25 mg Capsule 10's might cause kidney problems.
  • Regular blood tests are advised before and during treatment with Lenangio 25 mg Capsule 10's.

Disease/Condition Glossary

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cells called a plasma cell. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections.

Myelodysplastic syndromes: It is a group of disorders that occur due to abnormal functioning of blood cells. Symptoms include shortness of breath, anaemia, fatigue, need for blood transfusion, and risk of infections.

Mantle cell lymphoma: It is the cancer of the lymph tissue where the B-cells or B lymphocytes (a type of white blood cells) grow in an uncontrolled manner and build up in the lymph tissue, blood or bone marrow.

Follicular lymphoma: It is slow-growing cancer that affects B lymphocytes, a type of white blood cells that help fight infection. Incase of follicular lymphoma, too many B lymphocytes build up in the blood, lymph nodes, bone marrow, and spleen.

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