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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

LENALIDOMIDE-25MG

Manufacturer/Marketer :

Zee Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Lenozest 25 Capsule 30's

Lenozest 25 Capsule 30's belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenozest 25 Capsule 30's is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS where part of chromosome 5 is missing.
 
Lenozest 25 Capsule 30's contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenozest 25 Capsule 30's kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Lenozest 25 Capsule 30's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Lenozest 25 Capsule 30's if you are pregnant or breastfeeding. Lenozest 25 Capsule 30's may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Lenozest 25 Capsule 30's is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Lenozest 25 Capsule 30's must use effective contraception. Inform your doctor regarding your health condition and medications before taking Lenozest 25 Capsule 30's to rule out any interactions.

Uses of Lenozest 25 Capsule 30's

Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Lenozest 25 Capsule 30's as a whole with water; do not crush or chew it.

Medicinal Benefits

Lenozest 25 Capsule 30's belongs to the group of medicines called immunomodulatory agents. Lenozest 25 Capsule 30's is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenozest 25 Capsule 30's works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenozest 25 Capsule 30's kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Lenozest 25 Capsule 30's is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lenozest 25 Capsule 30's

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

Drug Warnings

Do not take Lenozest 25 Capsule 30's if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Lenozest 25 Capsule 30's if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Lenozest 25 Capsule 30's if you are breastfeeding as it is not unknown if it passes into breastmilk. Lenozest 25 Capsule 30's may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Lenozest 25 Capsule 30's is not recommended for use in children. Avoid consuming alcohol along with Lenozest 25 Capsule 30's as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

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LenalidomideRotavirus vaccine
Critical
LenalidomideYellow fever vaccine
Critical

Drug-Drug Interactions

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LenalidomideRotavirus vaccine
Critical
How does the drug interact with Lenozest 25 Capsule:
Administering the Rotavirus vaccine together with Lenozest 25 Capsule may increase the risk of infections.

How to manage the interaction:
Taking Lenozest 25 Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Lenozest 25 Capsule. Do not stop using any medications without consulting a doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Lenozest 25 Capsule:
When combining the Yellow fever vaccine with Lenozest 25 Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenozest 25 Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Lenozest 25 Capsule:
Combining the BCG vaccine with Lenozest 25 Capsule increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenozest 25 Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideAnakinra
Critical
How does the drug interact with Lenozest 25 Capsule:
Taking anakinra with Lenozest 25 Capsule can increase the risk of negative side effects.

How to manage the interaction:
Taking Lenozest 25 Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideLovastatin
Severe
How does the drug interact with Lenozest 25 Capsule:
The combination of lovastatin and Lenozest 25 Capsule may raise the risk of rhabdomyolysis, an uncommon but dangerous illness defined as the breakdown of skeletal muscle tissue.

How to manage the interaction:
There may be a possibility of interaction between Lenozest 25 Capsule and Lovastatin, but it can be taken if prescribed by a doctor. If you notice muscle weakness, pain, tenderness, or dark-coloured urine, contact your doctor immediately. These symptoms could be a sign of a condition called rhabdomyolysis, which can potentially harm your kidneys, especially if you already have kidney problems. Do not stop using any medications without talking to your doctor.
LenalidomideFingolimod
Severe
How does the drug interact with Lenozest 25 Capsule:
Taking Lenozest 25 Capsule with Fingolimod can increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction between Lenozest 25 Capsule and Fingolimod, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideDesogestrel
Severe
How does the drug interact with Lenozest 25 Capsule:
Using Lenozest 25 Capsule together with Desogestrel may increase the risk of blood clots.

How to manage the interaction:
Although taking Desogestrel and Lenozest 25 Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. if you experience any symptoms of blood clots such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
LenalidomideInfliximab
Severe
How does the drug interact with Lenozest 25 Capsule:
Taking Infliximab with Lenozest 25 Capsule can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although taking Lenozest 25 Capsule and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
LenalidomideConestat alfa
Severe
How does the drug interact with Lenozest 25 Capsule:
Taking Lenozest 25 Capsule and conestat alfa may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Lenozest 25 Capsule and conestat alfa, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideGolimumab
Severe
How does the drug interact with Lenozest 25 Capsule:
Taking Lenozest 25 Capsule and golimumab together may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction between Lenozest 25 Capsule and golimumab, it can be taken if prescribed by a doctor. However, contact a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.
  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Lenozest 25 Capsule 30's Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lenozest 25 Capsule 30's works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.

Do not stop taking Lenozest 25 Capsule 30's on your own. You are advised to take Lenozest 25 Capsule 30's for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lenozest 25 Capsule 30's.

No, it is not safe to father a child while taking Lenozest 25 Capsule 30's. Lenozest 25 Capsule 30's can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Lenozest 25 Capsule 30's and for at least 4weeks after discontinuing Lenozest 25 Capsule 30's, even if you have undergone a successful vasectomy. Male patients taking Lenozest 25 Capsule 30's must not donate semen whilst taking Lenozest 25 Capsule 30's and for 4weeks after discontinuing Lenozest 25 Capsule 30's.

Patients taking Lenozest 25 Capsule 30's must not donate blood during the treatment with Lenozest 25 Capsule 30's and for 1month after discontinuation of Lenozest 25 Capsule 30's as the donated blood might be given to pregnant women whose foetus should not be exposed to Lenozest 25 Capsule 30's since it causes severe birth defects.

People with multiple myeloma taking Lenozest 25 Capsule 30's may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Lenozest 25 Capsule 30's for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.

Lenozest 25 Capsule 30's might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Lenozest 25 Capsule 30's.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • ERYTHROPOIETIN

Special Advise

  • Do not take Lenozest 25 Capsule 30's if you are pregnant as it might cause severe birth defects or death of the unborn baby.
  • Male patients taking Lenozest 25 Capsule 30's must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.
  • You must not donate blood while taking Lenozest 25 Capsule 30's and for 4weeks after discontinuing Lenozest 25 Capsule 30's.
  • Lenozest 25 Capsule 30's might increase the risk of blood clots. Inform your doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of the arm or leg.
  • Lenozest 25 Capsule 30's might cause abnormal/increase in liver test results, inform the person doing the test that you are taking Lenozest 25 Capsule 30's.
  • Lenozest 25 Capsule 30's might increase/decrease your blood sugar levels. Regularly monitor blood glucose levels while taking Lenozest 25 Capsule 30's. Consult your doctor if you are diabetic.
  • Inform your doctor if you have any kidney dysfunction as Lenozest 25 Capsule 30's might cause kidney problems.
  • Regular blood tests are advised before and during treatment with Lenozest 25 Capsule 30's.

Disease/Condition Glossary

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cells called a plasma cell. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections.

Myelodysplastic syndromes: It is a group of disorders that occur due to abnormal functioning of blood cells. Symptoms include shortness of breath, anaemia, fatigue, need for blood transfusion, and risk of infections.

Mantle cell lymphoma: It is the cancer of the lymph tissue where the B-cells or B lymphocytes (a type of white blood cells) grow in an uncontrolled manner and build up in the lymph tissue, blood or bone marrow.

Follicular lymphoma: It is slow-growing cancer that affects B lymphocytes, a type of white blood cells that help fight infection. Incase of follicular lymphoma, too many B lymphocytes build up in the blood, lymph nodes, bone marrow, and spleen.

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