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  3. Relidomide 25 Capsule

Relidomide 25 Capsule, Pack of 1 Capsule
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
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Composition :

LENALIDOMIDE-25MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Relidomide 25 Capsule

Relidomide 25 Capsule belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Relidomide 25 Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS where part of chromosome 5 is missing.
 
Relidomide 25 Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Relidomide 25 Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Relidomide 25 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Relidomide 25 Capsule if you are pregnant or breastfeeding. Relidomide 25 Capsule may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Relidomide 25 Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Relidomide 25 Capsule must use effective contraception. Inform your doctor regarding your health condition and medications before taking Relidomide 25 Capsule to rule out any interactions.

Uses of Relidomide 25 Capsule

Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Relidomide 25 Capsule as a whole with water; do not crush or chew it.

Medicinal Benefits

Relidomide 25 Capsule belongs to the group of medicines called immunomodulatory agents. Relidomide 25 Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Relidomide 25 Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Relidomide 25 Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Relidomide 25 Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Storage

Keep Relidomide 25 Capsule out of reach and sight of children.
Side effects of Relidomide 25 Capsule
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

Do not take Relidomide 25 Capsule if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Relidomide 25 Capsule if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Relidomide 25 Capsule if you are breastfeeding as it is not unknown if it passes into breastmilk. Relidomide 25 Capsule may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Relidomide 25 Capsule is not recommended for use in children. Avoid consuming alcohol along with Relidomide 25 Capsule as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
LenalidomideRotavirus vaccine
Critical

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
How does the drug interact with Relidomide 25 Capsule:
Taking anakinra with Relidomide 25 Capsule can increase the risk of negative side effects.

How to manage the interaction:
Taking Relidomide 25 Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideRotavirus vaccine
Critical
How does the drug interact with Relidomide 25 Capsule:
Administering the Rotavirus vaccine together with Relidomide 25 Capsule may increase the risk of infections.

How to manage the interaction:
Taking Relidomide 25 Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Relidomide 25 Capsule. Do not stop using any medications without consulting a doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Relidomide 25 Capsule:
Combining the BCG vaccine with Relidomide 25 Capsule increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Relidomide 25 Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Relidomide 25 Capsule:
When combining the Yellow fever vaccine with Relidomide 25 Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Relidomide 25 Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideNatalizumab
Severe
How does the drug interact with Relidomide 25 Capsule:
Combining Relidomide 25 Capsule with Natalizumab can increase the chances of experiencing harmful side effects.

How to manage the interaction:
Although there is a possible interaction between Relidomide 25 Capsule and Natalizumab, you can take these medicines together if prescribed by your doctor. If you experience symptoms like infection, neurological problems, fever, diarrhea, or confusion, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
LenalidomideDienestrol
Severe
How does the drug interact with Relidomide 25 Capsule:
Taking Relidomide 25 Capsule together with dienestrol may increase the risk of dangerous blood clots.

How to manage the interaction:
Although there is an interaction between Relidomide 25 Capsule and dienestrol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideNivolumab
Severe
How does the drug interact with Relidomide 25 Capsule:
These drugs together may raise the likelihood of adverse effects.

How to manage the interaction:
There may be a possibility of interaction between Relidomide 25 Capsule and Nivolumab, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
LenalidomideDiethylstilbestrol
Severe
How does the drug interact with Relidomide 25 Capsule:
Taking Relidomide 25 Capsule together with diethylstilbestrol may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Relidomide 25 Capsule and diethylstilbestrol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideLeflunomide
Severe
How does the drug interact with Relidomide 25 Capsule:
Combining Relidomide 25 Capsule with Leflunomide can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Relidomide 25 Capsule and Leflunomide together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, contact your doctor right away. These symptoms include infection, liver problems, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.
LenalidomideTestosterone
Severe
How does the drug interact with Relidomide 25 Capsule:
Coadministration of Relidomide 25 Capsule with Testosterone can increase levels of testosterone in the blood.

How to manage the interaction:
Coadministration of Testosterone with Relidomide 25 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.
  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Side Effects of Relidomide 25 Capsule

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Relidomide 25 Capsule Substitute

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Relidomide 25 Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.

Do not stop taking Relidomide 25 Capsule on your own. You are advised to take Relidomide 25 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Relidomide 25 Capsule.

No, it is not safe to father a child while taking Relidomide 25 Capsule. Relidomide 25 Capsule can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Relidomide 25 Capsule and for at least 4weeks after discontinuing Relidomide 25 Capsule, even if you have undergone a successful vasectomy. Male patients taking Relidomide 25 Capsule must not donate semen whilst taking Relidomide 25 Capsule and for 4weeks after discontinuing Relidomide 25 Capsule.

Patients taking Relidomide 25 Capsule must not donate blood during the treatment with Relidomide 25 Capsule and for 1month after discontinuation of Relidomide 25 Capsule as the donated blood might be given to pregnant women whose foetus should not be exposed to Relidomide 25 Capsule since it causes severe birth defects.

People with multiple myeloma taking Relidomide 25 Capsule may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Relidomide 25 Capsule for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.

Relidomide 25 Capsule might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Relidomide 25 Capsule.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • ERYTHROPOIETIN

Special Advise

  • Do not take Relidomide 25 Capsule if you are pregnant as it might cause severe birth defects or death of the unborn baby.
  • Male patients taking Relidomide 25 Capsule must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.
  • You must not donate blood while taking Relidomide 25 Capsule and for 4weeks after discontinuing Relidomide 25 Capsule.
  • Relidomide 25 Capsule might increase the risk of blood clots. Inform your doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of the arm or leg.
  • Relidomide 25 Capsule might cause abnormal/increase in liver test results, inform the person doing the test that you are taking Relidomide 25 Capsule.
  • Relidomide 25 Capsule might increase/decrease your blood sugar levels. Regularly monitor blood glucose levels while taking Relidomide 25 Capsule. Consult your doctor if you are diabetic.
  • Inform your doctor if you have any kidney dysfunction as Relidomide 25 Capsule might cause kidney problems.
  • Regular blood tests are advised before and during treatment with Relidomide 25 Capsule.

Disease/Condition Glossary

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cells called a plasma cell. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections.

Myelodysplastic syndromes: It is a group of disorders that occur due to abnormal functioning of blood cells. Symptoms include shortness of breath, anaemia, fatigue, need for blood transfusion, and risk of infections.

Mantle cell lymphoma: It is the cancer of the lymph tissue where the B-cells or B lymphocytes (a type of white blood cells) grow in an uncontrolled manner and build up in the lymph tissue, blood or bone marrow.

Follicular lymphoma: It is slow-growing cancer that affects B lymphocytes, a type of white blood cells that help fight infection. Incase of follicular lymphoma, too many B lymphocytes build up in the blood, lymph nodes, bone marrow, and spleen.

Have a query?

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Relidomide 25 Capsule as it might cause increased dizziness.

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Pregnancy

Unsafe

Relidomide 25 Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Relidomide 25 Capsule as it is unknown if Relidomide 25 Capsule passes into breastmilk.

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Driving

Unsafe

Relidomide 25 Capsule may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Relidomide 25 Capsule is not recommended for children below 18years as the safety and effectiveness have not been established.

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