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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer

Lyceum Life Sciences Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Lycefenac 100/325/15 Tab

Lycefenac 100/325/15 Tab belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol and serratiopeptidase. Lycefenac 100/325/15 Tab is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase is an enzyme which helps in the breakdown of a protein (fibrin) which is formed as a by-product of the clotted blood at the site of injury. It thus causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue.

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage to the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal. 

You can take Lycefenac 100/325/15 Tab with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition.  Most of the side effects of Lycefenac 100/325/15 Tab do not require medical attention and gradually resolve over time. Common side effects include nausea, vomiting, indigestion, stomach pain etc. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Lycefenac 100/325/15 Tab if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Lycefenac 100/325/15 Tab

 Pain after any injury, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis, etc.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Lycefenac 100/325/15 Tab consists of aceclofenac, paracetamol and serratiopeptidase. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Paracetamol acts as mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue. Together these not only reduce pain and inflammation but also help in faster healing.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lycefenac 100/325/15 Tab

  • Nausea

  • Stomach Pain

  • Loss of appetite

  • Diarrhoea

  • Stomach upset

  • Indigestion

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Lycefenac 100/325/15 Tab as it may lead to an increase in the risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure and liver or kidney disease should not take Lycefenac 100/325/15 Tab on their own. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to painkillers like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Lycefenac 100/325/15 Tab . Use with caution in pregnancy and breastfeeding. Do not self-administer Lycefenac 100/325/15 Tab if you are pregnant or are nursing.

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
ParacetamolKetamine
Severe

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
How does the drug interact with Lycefenac 100/325/15 Tab:
Co-administration of Atenolol with Lycefenac 100/325/15 Tab could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Lycefenac 100/325/15 Tab, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Lycefenac 100/325/15 Tab:
Co-administration of ketamine and Lycefenac 100/325/15 Tab may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Lycefenac 100/325/15 Tab together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolOxazepam
Severe
How does the drug interact with Lycefenac 100/325/15 Tab:
Co-administration of Lycefenac 100/325/15 Tab may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Lycefenac 100/325/15 Tab, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Lycefenac 100/325/15 Tab:
Co-administration of Teriflunomide with Lycefenac 100/325/15 Tab may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Lycefenac 100/325/15 Tab with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Lycefenac 100/325/15 Tab:
Co-administration of Lycefenac 100/325/15 Tab and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Lycefenac 100/325/15 Tab and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Lycefenac 100/325/15 Tab:
Co-administration of Lycefenac 100/325/15 Tab and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Lycefenac 100/325/15 Tab and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Lycefenac 100/325/15 Tab:
Co-administration of Mipomersen with Lycefenac 100/325/15 Tab may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Lycefenac 100/325/15 Tab and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Lycefenac 100/325/15 Tab:
Co-administration of Lycefenac 100/325/15 Tab and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Lycefenac 100/325/15 Tab and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Lycefenac 100/325/15 Tab:
Co-administration of Lomitapide and Lycefenac 100/325/15 Tab may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Lycefenac 100/325/15 Tab and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.

  • In the chronic conditions of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.

  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit as little as possible, and only for short time (10-15 min). Use back support like rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Lycefenac 100/325/15 Tab Substitute

Substitutes safety advice
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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, in most of the patients it is safe to take Lycefenac 100/325/15 Tab but if it causes any unwanted side effects like diarrhea, vomiting, nausea, please consult your doctor immediately.

Lycefenac 100/325/15 Tab when taken by patients who are allergic to pain-killers or NSAIDs can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease and stomach ulcers,

A chronic inflammatory disorder affecting many joints, including those in the hands and feet. In rheumatoid arthritis, the body's immune system attacks its own tissue, including joints. In severe cases, it attacks internal organs. Rheumatoid arthritis affects joint linings, causing painful swelling.

Ankylosing spondylitis (AS) is a rare type of arthritis that causes pain and stiffness in your spine. This lifelong condition, also known as Bechterew disease, usually starts in your lower back. It can spread up to your neck or damage joints in other parts of your body.

No. Lycefenac 100/325/15 Tab is not indicated for stomach pain. If you have stomach pain refer to doctor as it may be sign of stomach ulcer or gastric bleeding.

Taking excessive alcohol with Lycefenac 100/325/15 Tab can cause liver damage. So, it is advisable to avoid or limit intake of alcohol during the treatment with Lycefenac 100/325/15 Tab .

Yes. But ensure pain killers or any other drugs you are taking does not contain paracetamol, aceclofenac or serratiopeptidase. As, it may lead to overdosage leading to unpleasant side effects. Always consult your doctor before using other medication.

Drug-Drug Interactions Checker List

  • NIMESULIDE
  • OXYPHENBUTAZONE
  • METAMIZOLE
  • WARFARIN

Special Advise

  • Paracetamol is a component of Lycefenac 100/325/15 Tab which can cause liver injury when in taken in large doses (usually more than 4 g/day). Concomitant use of alcohol is best avoided as it aggravates the liver toxicity.
  • Although Lycefenac 100/325/15 Tab provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve best results, it is strongly recommended remaining physically active as much as your condition allows. Adopting a healthy lifestyle coupled with healthy diet containing high proteins, is the mainstay of management of arthritic conditions.

Disease/Condition Glossary

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage of the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissues (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

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