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About Mesacol Suppository
Mesacol Suppository belongs to a class of anti-inflammatory drugs used to treat ulcerative colitis and ulcerative proctitis. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus. Ulcerative proctitis is a condition in which ulcerative colitis solely affects the rear channel (rectum).
Mesacol Suppository contains Mesalamine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling). This lowers ulceration, bleeding, and stomach pain while preventing future illness flare-ups.
Use Mesacol Suppository as directed by your physician. Sometimes, you may experience diarrhoea, stomach pain, headache or nausea. Most of these side effects of Mesacol Suppository do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Before taking the Mesacol Suppository, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you have severe kidney or liver failure or blood abnormalities like porphyria. Mesacol Suppository should not be used in pregnant and breastfeeding mothers unless necessary. So, inform your doctor if you are pregnant or breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Mesacol Suppository.
Uses of Mesacol Suppository

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Directions for Use
Key Benefits
Mesacol Suppository contains Mesalamine, an anti-inflammatory drug used to treat ulcerative colitis and ulcerative proctitis. It can also help treat other inflammatory bowel disease types, such as Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping reduce inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Mesacol Suppository may prevent further episodes of ulcerative colitis. It is especially useful when ulcerative colitis symptoms affect the rectum.
Storage
Drug Warnings
Before taking the Mesacol Suppository, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Do not use Mesacol Suppository if you are pregnant, planning to become pregnant, or breastfeeding without first consulting the doctor. Mesacol Suppository is recommended not to be used in populations with severe renal or hepatic impairment, so inform your doctor if you have severe renal or hepatic impairment. Use Mesacol Suppository in dose and duration as advised by a doctor only. Do not swallow Mesacol Suppository. In case of accidental swallowing, drink plenty of water and consult a doctor immediately.
Drug-Drug Interactions
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Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Alcohol
Safe if prescribed
The interaction of alcohol with Mesacol Suppository is unknown. However, avoid consuming alcohol while on treatment with this medicine.
Pregnancy
Consult your doctor
Mesacol Suppository should not be used in pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Mesacol Suppository.
Breast Feeding
Consult your doctor
Mesacol Suppository should not be used while breastfeeding unless necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Mesacol Suppository.
Driving
Safe if prescribed
Mesacol Suppository usually does not affect your ability to drive or operate machinery.
Liver
Consult your doctor
Inform your doctor before receiving Mesacol Suppository if you have a history of liver diseases/conditions. It should be used cautiously in patients with mild to moderately impaired liver function. It is recommended not to be used in populations with severe liver impairment.
Kidney
Consult your doctor
Inform your doctor before receiving Mesacol Suppository if you have a history of kidney diseases/conditions. It should be used cautiously in patients with mild to moderately impaired kidney function. It is recommended not to be used in populations with severe kidney impairment.
Children
Safe if prescribed
Mesacol Suppository is intended for adults. Not recommended for children.
Mesacol Suppository contains Mesalamine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (swelling) in the intestines and relieves stomach pain or bleeding symptoms.
Mesacol Suppository may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while using Mesacol Suppository to prevent dehydration.
If you miss a dosage of mesalamine, take it as soon as you remember unless your next dose is approaching. In this situation, skip the missed dose and resume your regular schedule. Do not combine two doses to make up for a missed dosage.
You are recommended not to take Mesacol Suppository with other medications without doctor's notice, especially immunosuppressant medications such as Azathioprine.
No, you are not recommended to stop using Mesacol Suppository suddenly as it may cause recurring symptoms. Therefore, use Mesacol Suppository for as long as your doctor has prescribed it, and if you experience any difficulty while using Mesacol Suppository, please consult your doctor.
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