Mesacol OD Tablet 15's

Written By Sureshvarma D , MPharma

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹577.5

(Inclusive of all Taxes)

₹86.6 Cashback (15%)

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Prescription drug

Whats That

About Mesacol OD Tablet

Mesacol OD Tablet belongs to a class of drugs called 'anti-inflammatory drugs used to treat ulcerative colitis and Crohn’s disease. Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus.

Mesacol OD Tablet contains Mesalamine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Take Mesacol OD Tablet as prescribed. You are advised to use Mesacol OD Tablet for as long as your doctor has recommended it for you based on your medical condition. In some cases, you may experience diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). Most of these side effects of Mesacol OD Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to any components present in Mesacol OD Tablet . Mesacol OD Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Mesacol OD Tablet . Mesalamine tablet is not recommended for children below two years, and granules are not recommended for children below six years. However, Mesacol OD Tablet should be given to children only if advised by a doctor. Avoid taking Mesacol OD Tablet if you have severe kidney failure. If you have stomach pain, cramps, severe headache, fever or rash, stop taking Mesacol OD Tablet immediately and consult a doctor.

Uses of Mesacol OD Tablet

Ulcerative colitis, Crohn’s disease

Directions for Use

Tablet: Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Granules: Empty the contents directly on the tongue and drink some water or orange juice. They can also be mixed with yoghurt and should be taken immediately without chewing on granules.Pellets: Check the label for directions before use and take it as advised by the doctor.

Medicinal Benefits

Mesacol OD Tablet contains Mesalamine, an anti-inflammatory drug used to treat ulcerative colitis and Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping reduce inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Mesacol OD Tablet may prevent further episodes of ulcerative colitis.

Storage

Keep Mesacol OD Tablet out of the sight and reach of children.

Side effects of Mesacol OD Tablet

Burps

Eating and drinking slowly can help swallow less air, which reduces burps.
Avoid consuming foods like gum and hard candy and drinking carbonated drinks as they release carbon dioxide gas in your body.
Prevent smoking as it can impact your whole body.
Seek medical help to treat gastric problems and heart burn that may lead to frequent burps.
Check your dentures because if they are loosely fit, excess air can be swallowed that causes burbs more frequently.

Bowel Inflammation

If you have bowel inflammation, eat smaller quantities and more frequent meals.
Eat slowly and chew your food thoroughly to help digestion.
Eat fiber-rich foods such as fruits, whole grains, and vegetables to promote regular bowel movements.
Avoid gas-producing foods like cabbage, beans, broccoli and carbonated drinks.
Drink lots of water throughout the day to prevent dehydration and aid digestion.
Do regular exercise to enhance digestion and reduce bloating.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Pain

Apply a hot/cold pack to the affected area.
Doing gentle exercises can help cope with pain by stretching muscles.
Get enough sleep. It helps enhance mood and lower pain sensitivity.
Avoid alcohol, smoking and tobacco as they can increase pain.
Follow a well-balanced meal.
Meditation and massages may also help with pain.

Common Cold

Here are the steps to manage the medication-triggered Common Cold:

Inform your doctor about the common cold symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Itching

Here are the few steps for dealing with itching caused by drug use:

Report the itching to your doctor immediately; they may need to change your medication or dosage.
Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
Try not to scratch, as this can worsen the itching and irritate your skin.
If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Drug Warnings

Inform your doctor if you're allergic to any ingredient in the Mesacol OD Tablet . Mesacol OD Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, inform your doctor before taking Mesacol OD Tablet . Avoid taking Mesacol OD Tablet if you have severe kidney failure. Severe skin reactions such as toxic epidermal necrolysis (skin peeling and blistering) or Stevens-Johnson syndrome (a painful rash that spreads and blisters) can occur in some patients taking Mesacol OD Tablet . Therefore, if you notice any skin reactions while taking Mesacol OD Tablet , please consult a doctor immediately. If you have stomach pain, cramps, severe headache, fever or rash, stop taking Mesacol OD Tablet immediately and consult a doctor. Avoid taking Mesacol OD Tablet if you have had blood abnormalities or kidney problems while taking other medicines such as Sulphasalazine.

Drug-Drug Interactions

MesalazineCidofovir

Critical

MesalazineIomeprol

Severe

Drug-Drug Interactions

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MesalazineCidofovir

Critical

How does the drug interact with Mesacol OD Tablet:
Co-administration of Mesacol OD Tablet with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Mesacol OD Tablet with Cidofovir is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.

MesalazineIomeprol

Severe

How does the drug interact with Mesacol OD Tablet:
Co-administration of Iomeprol with Mesacol OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesacol OD Tablet and Iomeprol they can be taken together if your doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.

MesalazineRanitidine

Severe

How does the drug interact with Mesacol OD Tablet:
Co-administration of Ranitidine with Mesacol OD Tablet can decrease the levels of Mesacol OD Tablet, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Mesacol OD Tablet with Ranitidine, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.

MesalazineTenofovir alafenamide

Severe

How does the drug interact with Mesacol OD Tablet:
Co-administration of Tenofovir alafenamide with Mesacol OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
There is a possibility of interaction between Mesacol OD Tablet with Tenofovir alafenamide, but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience increased or decreased urination, swelling, shortness of breath, bone pain, cramping in the muscles. Do not discontinue the medication without consulting a doctor.

MesalazineIodamide

Severe

How does the drug interact with Mesacol OD Tablet:
Co-administration of Iodamide with Mesacol OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalamine with Iodamine they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, itchy skin, shortness of breath, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.

MesalazineMetrizamide

Severe

How does the drug interact with Mesacol OD Tablet:
Co-administration of Metrizamide with Mesacol OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesacol OD Tablet with Metrizamide they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, dry, itchy skin, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.

MesalazineNizatidine

Severe

How does the drug interact with Mesacol OD Tablet:
Co-administration of Nizatidine with Mesacol OD Tablet can decrease the level or effect of Mesalamine by increasing gastric pH.

How to manage the interaction:
Although there may be a possible interaction between Mesacol OD Tablet with Nizatidine, they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.

MesalazineDeferasirox

Severe

How does the drug interact with Mesacol OD Tablet:
Co-administration of Deferasirox with Mesacol OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possibility of interaction between Mesacol OD Tablet and Deferasirox but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as increased or decreased urination, abrupt weight gain or loss, weakness, or dizziness. Do not discontinue the medication without consulting a doctor.

MesalazineOmeprazole

Severe

How does the drug interact with Mesacol OD Tablet:
Co-administration of omeprazole with Mesacol OD Tablet can decrease the effects of Mesacol OD Tablet.

How to manage the interaction:
There could be a possible interaction between Mesacol OD Tablet and omeprazole, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley, and berries, to help heal faster.
Include olive oil and omega-3 fatty acids.
Eat more fibre-rich foods such as fruits and vegetables.
Limit dairy intake as your body may develop difficulty digesting certain dairy products when affected with Crohn’s disease, leading to stomach cramps, diarrhoea, or stomach upset.
Drink plenty of water to prevent dehydration.

Side Effects of Mesacol OD Tablet

Diarrhoea
Stomach pain
Headache
Nausea
Vomiting
Flatulence (gas)

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

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Author Details

Written By

Sureshvarma D

MPharma

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Mesacol OD Tablet work?

Mesacol OD Tablet contains Mesalamine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (swelling) in the intestines and relieves stomach pain or bleeding symptoms.

Does Mesacol OD Tablet cause diarrhoea?

Yes, Mesacol OD Tablet may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools, or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Mesacol OD Tablet to prevent dehydration.

Can I take Mesacol OD Tablet with pain killer like Ibuprofen?

You are not recommended to take Mesacol OD Tablet with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Mesacol OD Tablet with other medicines.

Does Mesacol OD Tablet cause kidney stones?

Yes, Mesacol OD Tablet may cause kidney stones in some patients. It is not necessary for everyone taking Mesacol OD Tablet to experience this side effect. However, if you notice blood in urine or pain in the sides of the stomach, please consult a doctor immediately. Drink adequate water while taking Mesacol OD Tablet to prevent kidney stones.

Is Mesacol OD Tablet safe for patients with stomach ulcer?

Mesacol OD Tablet should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Mesacol OD Tablet .

Does Crohn’s disease cause lactose intolerance?

Some people may develop lactose intolerance (inability to digest lactose) when affected by Crohn’s disease. Therefore, it is recommended to avoid dairy products if you have Crohn’s disease as it may lead to adverse effects such as diarrhoea, stomach cramps, or stomach upset.

Drug-Drug Interactions Checker List

LACTULOSE
ASPIRIN
IBUPROFEN
AZATHIOPRINE
THIOGUANINE
MERCAPTOPURINE

Special Advise

Blood and urine tests are recommended before and during the treatment with Mesacol OD Tablet to monitor the functioning of the kidney, liver, and blood.

Disease/Condition Glossary

Ulcerative colitis: Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the lining of the large intestine (colon) and produces ulcers on the lining of the colon, which may cause bleeding and discharge of pus and mucus. The common symptoms include bloody stools, stomach pain, rectal pain, diarrhoea, fever, or weight loss. Additionally, it may cause other problems such as joint pain or swelling, mouth sores, skin problems, decreased appetite, or nausea. The factors involved in causing ulcerative colitis include immune disorders, environmental factors like viruses, bacteria, or antigens, which may trigger the immune system, and genes inherited from the parent.

Crohn’s disease: Crohn’s disease is a type of chronic inflammatory bowel disease that can affect any part of the gastrointestinal tract, from mouth to anus. But mostly occurs in the small intestine and large intestine. The symptoms include blood in stools, stomach cramps, tiredness, diarrhoea, fever, weight loss, or loss of appetite.