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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Methygin Tablet

Methygin Tablet belongs to the class of medication called semi-synthetic ergot alkaloids used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.

Methygin Tablet contains Methylergometrine which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Take Methygin Tablet exactly as prescribed by the doctor. In some cases, Methygin Tablet may cause high blood pressure associated with seizures and/or headache, nausea, and vomiting. If the side effects persist or worsen, consult your doctor.

Do not take Methygin Tablet if you are pregnant. Consult your doctor if you are breastfeeding. Methygin Tablet is not recommended for children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Methygin Tablet

Postpartum haemorrhage

Directions for Use

Swallow Methygin Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Methygin Tablet is indicated in the prevention and control of postpartum haemorrhage. It is used following delivery of the placenta for the routine management of uterine atony (soft and weak uterus after childbirth), subinvolution of the uterus, and haemorrhage. Methygin Tablet contains Methylergometrine, a semi-synthetic ergot alkaloid which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Storage

Store in a cool and dry place away from sunlight
Side effects of Methygin Tablet
  • Stress levels should be managed by practicing yoga and meditation regularly.
  • Maintain a proper sleeping schedule.
  • Maintain a balanced diet containing low glycemic index like fruits, vegetables, proteins and grains.
  • Do not consume alcohol.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Do not take Methygin Tablet if you are allergic to any of its components, if you have high blood pressure, toxaemia (a complication of pregnancy characterised by high blood pressure), or if you are pregnant. Inform your doctor if you have coronary artery disease, sepsis, vascular disease, or liver or kidney impairment. Consult your doctor if you are breastfeeding. The safety and effectiveness of Methygin Tablet in children have not been established. Let your doctor know if you are taking prescription/non-prescription medicines, including herbal products and supplements.

Drug-Drug Interactions

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MethylergometrineVoriconazole
Critical
MethylergometrineKetoconazole
Critical

Drug-Drug Interactions

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MethylergometrineVoriconazole
Critical
How does the drug interact with Methygin Tablet:
Coadministration of Methygin Tablet with Voriconazole may increase the blood level of Methygin Tablet.

How to manage the interaction:
Although Methygin Tablet with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineKetoconazole
Critical
How does the drug interact with Methygin Tablet:
Using Ketoconazole with Methygin Tablet can increase the concentration of Methygin Tablet, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Methygin Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineSumatriptan
Critical
How does the drug interact with Methygin Tablet:
Coadministration of Sumatriptan with Methygin Tablet can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with Methygin Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MethylergometrineItraconazole
Critical
How does the drug interact with Methygin Tablet:
Co-administration of Methygin Tablet and Itraconazole may increase the blood levels of Methygin Tablet.

How to manage the interaction:
Methygin Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
MethylergometrineClarithromycin
Critical
How does the drug interact with Methygin Tablet:
When Methygin Tablet is taken with Clarithromycin, the amount of Methygin Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with Methygin Tablet is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
MethylergometrineGlyceryl trinitrate
Critical
How does the drug interact with Methygin Tablet:
Coadministration of Methygin Tablet with Glyceryl trinitrate can increase the levels and side effects of Methygin Tablet.

How to manage the interaction:
Taking Methygin Tablet with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
MethylergometrineRitonavir
Critical
How does the drug interact with Methygin Tablet:
Taking Methygin Tablet with Ritonavir can significantly increase the blood levels and effects of Methygin Tablet.

How to manage the interaction:
Taking Methygin Tablet with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylergometrinePhenylephrine
Severe
How does the drug interact with Methygin Tablet:
Taking Phenylephrine with Methygin Tablet can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with Methygin Tablet can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.
MethylergometrineEphedrine
Severe
How does the drug interact with Methygin Tablet:
Taking Ephedrine with Methygin Tablet may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with Methygin Tablet may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of Methygin Tablet with Grapefruit and Grapefruit may lead to an increase in the effectiveness of Methygin Tablet. Avoid or limit grapefruit and grapefruit juice consumption with Methygin Tablet. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

  • Include high-fibre foods such as fruits and whole grains.
  • Drink plenty of fluids such as water, fruit juices, and milk.
  • Limit processed/packaged foods, high salt/sugary foods and saturated fats.
  • Get plenty of rest.
  • Eat healthy meals and exercise appropriately.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Methygin Tablet Substitute

Substitutes safety advice
  • Methergin Tablet 10's

    by Others

    8.80per tablet
  • Ergostat Tablet 10's

    by AYUR

    9.00per tablet
  • Nugine 0.125mg Tablet

    by Others

    6.30per tablet
  • Mormet 0.125mg Tablet

    by Others

    3.57per tablet
  • Memjet Tablet 10's

    by Others

    9.00per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Methygin Tablet works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Methygin Tablet is not recommended for use in people with high blood pressure. Consult your doctor if you have hypertension.

Methygin Tablet may cause nausea or vomiting as a side effect. It is not necessary for everyone taking Methygin Tablet to experience this side effect. However, if the condition persists or worsens, consult your doctor.

Methygin Tablet may be indicated in the management of uterine atony. Uterine atony refers to a weak and soft uterus after childbirth.

Drug-Drug Interactions Checker List

  • DIHYDROERGOTAMINE
  • ERGOTAMINE
  • ERYTHROMYCIN
  • TROLEANDOMYCIN
  • CLARITHROMYCIN
  • RITONAVIR
  • INDINAVIR
  • NELFINAVIR
  • DELAVIRDINE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE

Special Advise

 

Disease/Condition Glossary

Postpartum haemorrhage: It is a condition in which excessive bleeding occurs following childbirth. This can lead to a drop in blood pressure. Symptoms include vaginal bleeding that does not stop. Loss of tone in uterine muscles and bleeding disorder could be the causes of postpartum haemorrhage.

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