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Reviewed By Sunny S , MBBS

About Mifebase 25 Tablet 10's

Mifebase 25 Tablet 10's belongs to the class of medication called 'progestin antagonist' used in combination with Misoprostol to induce a medical abortion. Mifebase 25 Tablet 10's is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help.

Mifebase 25 Tablet 10's contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Mifebase 25 Tablet 10's to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete.

Having a medical abortion is a very emotional decision. You should be mentally prepared for all the risks a surgical absorption could lead to, like incomplete abortion, heavy and prolonged bleeding (which may last up to 30 days), fever, and digestive system discomfort. Also, if the medication does not work, it can lead to an unwanted ongoing pregnancy, leading to fetal defects. So, to avoid any complications, keep in regular touch with your doctor and do as advised.

Mifebase 25 Tablet 10's should be taken in dose and duration as advised by the doctor, preferably with food. It would be best to take it at a fixed time every day. It is a tablet and should be taken orally with a glass of water. In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Mifebase 25 Tablet 10's subside with time. But if your vaginal bleeding does not, please visit the doctor immediately, and it requires immediate medical attention.

Mifebase 25 Tablet 10's should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting Mifebase 25 Tablet 10's if you have or ever had an ectopic pregnancy (when the fetus grows in the fallopian tube), using an intrauterine device, or if you are breastfeeding, any bleeding disorder or heart problem. Do not do strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Mifebase 25 Tablet 10's

Medical abortion

Medicinal Benefits

Mifebase 25 Tablet 10's contains Mifepristone, which is taken in a regimen with Misoprostol to induce medical abortion or terminate a pregnancy before 70 days. It works by blocking the effect of progesterone (female hormone) needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Mifebase 25 Tablet 10's to show effect.

Side Effects of Mifebase 25 Tablet 10's

  • Weakness
  • Nausea
  • Uterine cramps
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Infection following abortion
  • Uterine bleeding

Directions for Use

Mifebase 25 Tablet 10's should be taken in dose and duration as prescribed by your doctor. Do not chew or crush it; swallow it as a whole.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Women who have an ectopic pregnancy (a pregnancy outside of the uterus, problems with the adrenal glands (the glands near the kidneys), currently taking corticosteroid therapy (medications), have an allergic reaction to mifepristone, misoprostol or similar drugs, have bleeding problems or taking the blood-thinning drug (warfarin, clopidogrel, aspirin, heparin etc.) should not use Mifebase 25 Tablet 10's and contact doctor. After using Mifebase 25 Tablet 10's if you start feeling sleepy, do not drive or operate heavy machinery. If you use an intrauterine device (IUD), please remove it before taking the Mifebase 25 Tablet 10's. Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (herbal supplements to treat mild depression) and grapefruit juice should not be taken when taking Mifebase 25 Tablet 10's as it is known to interact. 

Therapeutic Class

ANTIPROGESTERONE

Drug-Drug Interactions

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MifepristoneTriamcinolone
Critical
MifepristoneSirolimus
Critical

Drug-Drug Interactions

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MifepristoneTriamcinolone
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
Using Mifebase 25 Tablet 10's with Triamcinolone can significantly reduce the effects of triamcinolone.

How to manage the interaction:
Taking Triamcinolone with Mifebase 25 Tablet 10's is not recommended but can be taken if prescribed by a doctor. However, if you notice any unusual symptoms contact a doctor. Do not discontinue any medications without consulting a doctor.
MifepristoneSirolimus
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
Coadministration of Sirolimus with Mifebase 25 Tablet 10's can increase the levels of Sirolimus in the blood, which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Sirolimus with Mifebase 25 Tablet 10's is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.
MifepristoneConivaptan
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
When Mifebase 25 Tablet 10's is taken with Conivaptan, it may increase the risk of negative side effects.

How to manage the interaction:
Taking Mifebase 25 Tablet 10's with Conivaptan is not recommended as it leads to an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as seizures(fits), difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
MifepristoneErgotamine
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
When Mifebase 25 Tablet 10's is taken with Ergotamine, it may increase the blood levels of Ergotamine, which may result in side effects.

How to manage the interaction:
Taking Ergotamine with Mifebase 25 Tablet 10's is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
MifepristoneFluticasone furoate
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
Using Fluticasone furoate with Mifebase 25 Tablet 10's can reduce the effect of fluticasone furoate.

How to manage the interaction:
Taking Fluticasone furoate with Mifebase 25 Tablet 10's is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
MifepristoneLurasidone
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
Coadministration of Lurasidone with Mifebase 25 Tablet 10's can increase the levels of Lurasidone which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Lurasidone with Mifebase 25 Tablet 10's together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any abnormal muscle movements, seizures(fits), high blood sugar, dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MifepristoneDalteparin
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
Combining Mifebase 25 Tablet 10's with Dalteparin can increase the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Dalteparin with Mifebase 25 Tablet 10's may possibly lead to an interaction, they can be taken if a doctor prescribes it. Emergency medical attention may be needed for persistent, excessive bleeding. Without consulting a doctor. Do not stop using any medications without talking to a doctor.
MifepristoneMidazolam
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
Co-administration of Mifebase 25 Tablet 10's and Midazolam may significantly increase Midazolam blood levels and effects, which increases the risk of side effects.

How to manage the interaction:
Although taking Mifebase 25 Tablet 10's and Midazolam together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MifepristoneBudesonide
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
Using Mifebase 25 Tablet 10's together with budesonide may significantly reduce the effects of budesonide.

How to manage the interaction:
Taking Budesonide with Mifebase 25 Tablet 10's is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
MifepristoneApixaban
Critical
How does the drug interact with Mifebase 25 Tablet 10's:
Mifebase 25 Tablet 10's and Apixaban co-administration have been associated with more severe vaginal bleeding in women.

How to manage the interaction:
Taking Apixaban with Mifebase 25 Tablet 10's together is not generally recommended as it may lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience persistent, excessive bleeding, consult the doctor. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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MIFEPRISTONE-25MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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MIFEPRISTONE-25MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may increase the effects of Mifebase 25 Tablet 10's. Avoid consumption of grape juice while taking Mifebase 25 Tablet 10's. However, if you experience headache, dizziness, fatigue, nausea, vomiting, cramping, diarrhea, swelling, and high blood pressure, consult the doctor.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DEXAMETHASONE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • PHENOBARBITAL
  • CARBAMAZEPINE
  • CYCLOSPORINE
  • TACROLIMUS
  • SIROLIMUS
  • ERGOTAMINE

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.
  • Avoid chronic stress and physical exercise like running, as it might increase vaginal bleeding.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Get an ultrasound to check if the abortion is done completely to avoid unwanted complications.
  • Try to include heart-healthy omega-3 fatty acid-containing foods or drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Special Advise

  • Mifebase 25 Tablet 10's should not be used to end the pregnancy after ten weeks.
  • Contact your doctor immediately if you experience heavy vaginal bleeding after taking this medicine.

Disease/Condition Glossary

Medical abortion: It is a procedure in which medicine is used to end a pregnancy. It is effectively causing abortion if performed in the first 70 days of pregnancy. Vagina bleeding occurs, and if it does not stop, please inform your doctor as it might require medical supervision. Having a medical abortion is a very emotional decision. You should be mentally prepared for all the risks a surgical absorption could lead to, like incomplete abortion, heavy and prolonged bleeding (which may last up to 30 days), fever, and digestive system discomfort. Also, if the medication does not work, it can lead to an unwanted ongoing pregnancy, leading to fetal defects. So, to avoid any complications, keep in regular touch with your doctor and do as advised. 

Mifebase 25 Tablet 10's Substitute

Substitutes safety advice
  • MEFI 25 TABLETS 10'S

    by AYUR

    50.58per tablet
  • Fibrobest-M 25Mg Tab 10'S

    by Others

    58.50per tablet
  • Legicare 25 Tablet 10's

    by Others

    50.40per tablet
  • Fibristone 25 Tablet 10's

    by AYUR

    59.27per tablet
  • Fibroease 25mg Tablet 10's

    by AYUR

    68.85per tablet
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